(3R, 5R) -tert-Butyl 7- [2- (4-fluorophenyl) -5-isopropyl-3-phenyl-4- (phenylcarbamoyl) -1H-pyrrol-1-yl] -3, what is the chemical structure of 5-dihydroxyheptanoate

This is the name of the organic compound. According to this name, if you want to draw its chemical structure, you need to follow the rules of organic chemistry and gradually analyze it.

First look at the part of " (3R, 5R) -tert-Butyl 3,5 -dihydroxyheptanoate", which is the main chain structure of the molecule. " (3R, 5R) " chiral carbon configuration, "tert-Butyl" is tert-butyl, connected to the main chain; "3,5 -dihydroxyheptanoate" epiheptanoate structure, and there are hydroxyl groups at positions 3 and 5.

Look again at "7- [2- (4 -fluorophenyl) -5 -isopropyl -3 -phenyl -4 - (phenylcarbamoyl) -1H -pyrrol -1 -yl]", which is a substituent connected to the 7-position of the main chain. "2- (4 -fluorophenyl) " shows p-fluorophenyl at the 2-position of the pyrrole ring; "5 -isopropyl" epipyrrole ring has isopropyl at the 5-position; "3 -phenyl" epipyrrole ring has phenyl at the 3-position; "4- (phenylcarbamoyl) " epipyrrole ring is connected to benzoylamino at the 4-position.

Overall, its chemical structure is based on heptanoate containing tert-butyl, 3 and 5 hydroxyl groups as the main chain, and 7-position pyrrole groups with specific substitutions. However, it is difficult to draw intuitively, so I can only analyze its structural elements in detail with text, hoping to help you imagine the chemical structure of this compound.

(3R, 5R) -tert-Butyl 7- [2- (4-fluorophenyl) -5-isopropyl-3-phenyl-4- (phenylcarbamoyl) -1H-pyrrol-1-yl] -3, What are the physical properties of 5-dihydroxyheptanoate

(3R, 5R) -tert-butyl 7- [2 - (4 - fluorophenyl) - 5 - isopropyl - 3 - phenyl - 4 - (phenylcarbamoyl) - 1H - pyrrole - 1 - yl] - 3,5 - dihydroxyheptanoate The physical properties of this substance are of great value to explore.

Looking at its shape, it is a white to off-white crystalline powder at room temperature, with a fine texture, like snow falling in the early winter, pure and soft. This shape is easy to store and use, and is also conducive to subsequent preparation processing.

When it comes to the melting point, it has been accurately determined to be in a specific temperature range. This temperature is the critical value of its transition from solid to liquid, just like the turning point in the development of things, marking the change of material states. The exact value of the melting point is of great significance for identifying the compound and controlling its purity.

In terms of solubility, it shows a certain solubility in common organic solvents, such as ethanol and acetone. In ethanol, with the increase of temperature, the solubility also increases, as if ice and snow meet the warm sun and gradually melt. In water, its solubility is relatively low, and only a very small amount can be dissolved, which seems to build an invisible barrier in water to prevent it from dissolving in large quantities.

Density is also a property that cannot be ignored. Its density is determined by measurement, and this value reflects the mass per unit volume of the substance, which is like a standard for measuring its "weight". It plays a key guiding role in many practical application scenarios, such as the material ratio in chemical production.

In addition, the refractive index of the compound also has a specific value. When light passes through this object, refraction occurs, and the refractive index is a parameter to measure the degree of refraction, just like the "trajectory code" of light traveling through it, providing important clues for the study of its optical properties.

All these physical properties provide a key basis for in-depth understanding of (3R, 5R) -tert-butyl 7- [2- (4-fluorophenyl) -5-isopropyl-3-phenyl-4- (phenylaminoyl) -1H-pyrrole-1-yl] -3,5-dihydroxyheptanoate, which is indispensable in many fields such as scientific research and production.

(3R, 5R) -tert-Butyl 7- [2- (4-fluorophenyl) -5-isopropyl-3-phenyl-4- (phenylcarbamoyl) -1H-pyrrol-1-yl] -3, what is the synthesis method of 5-dihydroxyheptanoate

To prepare (3R, 5R) -tert-butyl 7- [2 - (4 - fluorophenyl) - 5 - isopropyl - 3 - phenyl - 4 - (phenylaminoyl) - 1H - pyrrole - 1 - yl] - 3,5 - dihydroxyheptanoate, the synthesis method should follow the chemical principle and follow the rules of the reaction.

First, a suitable starting material is taken, and (3R, 5R) -tert-butyl dihydroxyheptanoate is used as the base. This ester has a specific three-dimensional configuration, which lays the foundation for the desired chiral structure of the product. Then find the reagent containing fluorophenyl, isopropyl, phenyl and pyrrole structures. In this reagent, 4-fluorophenyl, isopropyl, phenyl and other groups are gradually constructed in the follow-up reaction.

First, (3R, 5R) -tert-butyl dihydroxyheptanoate interacts with the activation reagent to activate the hydroxyl group and improve its reactivity. Later, pyrrole derivatives containing specific substituents are introduced. In this step, the reaction conditions such as temperature, solvent, catalyst, etc. need to be precisely regulated. If the temperature is too high, side reactions may occur; if the temperature is too low, the reaction will be delayed and the yield will be low. A suitable organic solvent is selected to facilitate the full dissolution and contact of the reactants, so that the reaction can proceed smoothly. The addition of a catalyst can reduce the activation energy of the reaction and speed up the reaction rate.

After the pyrrole derivative is connected, the aminoformylation reaction is carried out, and the phenylcarbamoyl group is introduced. This process requires fine control of the reaction process to prevent overreaction or formation of isomers.

After the reaction is completed, the impurities are removed by separation and purification techniques, such as column chromatography, recrystallization, etc., to obtain pure (3R, 5R) -tert-butyl 7- [2- (4-fluorophenyl) -5-isopropyl-3-phenyl-4- (phenylaminoyl) -1H-pyrrole-1-yl] -3,5-dihydroxyheptanoate products. Each step requires rigorous operation to achieve the purpose of synthesis and obtain the expected product.

(3R, 5R) -tert-Butyl 7- [2- (4-fluorophenyl) -5-isopropyl-3-phenyl-4- (phenylcarbamoyl) -1H-pyrrol-1-yl] -3, what are the application fields of 5-dihydroxyheptanoate

(3R, 5R) -tert-butyl 7- [2 - (4 - fluorophenyl) - 5 - isopropyl - 3 - phenyl - 4 - (phenylcarbamoyl) - 1H - pyrrole - 1 - yl] - 3,5 - dihydroxyheptanoate, this compound is more common in the field of pharmaceutical chemistry, in the development of lipid-lowering drugs, promising.

In the field of Guanfu medicine, it is difficult to adjust fat for a long time. The disease of hyperlipidemia is caused by the disharmony of the viscera, the transportation and transformation of the plaster, and the dipping into various malignant diseases, such as atherosclerosis, heart and brain diseases, etc. (3R, 5R) -tert-butyl 7- [2- (4-fluorophenyl) -5-isopropyl-3-phenyl-4- (phenylaminoformyl) -1H-pyrrole-1-yl] -3,5-dihydroxyheptanoate, or can intervene in the path of lipid metabolism. It may be able to modulate the activity of hydroxymethylglutaryl-CoA reductase, which plays an important role in the synthesis of cholesterol. By inhibiting its activity, it can reduce the production of cholesterol and normalize the level of lipids in the blood, so as to prevent and treat high-fat diseases and protect the health of the heart and brain.

In the process of creating new drugs, this compound may be a precursor due to its unique structure. According to its structure, researchers can increase or decrease it, and carefully carve it to find new agents with better activity and especially minor side effects. Therefore, in the corner of pharmaceutical research and development, (3R, 5R) -tert-butyl 7- [2 - (4 - fluorophenyl) - 5 - isopropyl - 3 - phenyl - 4 - (phenylcarbamoyl) - 1H - pyrrole - 1 - yl] - 3,5 - dihydroxyheptanoate is of great research value and is expected to provide a new path for the treatment of high fat and related diseases.

(3R, 5R) -tert-Butyl 7- [2- (4-fluorophenyl) -5-isopropyl-3-phenyl-4- (phenylcarbamoyl) -1H-pyrrol-1-yl] -3, what is the market prospect of 5-dihydroxyheptanoate

There is now a product named\ ((3R, 5R) \) -tert-butyl\ (7- [2- (4-fluorophenyl) -5 -isopropyl-3-phenyl-4- (phenylaminoformyl) -1H -pyrrole-1-yl] -3,5 -dihydroxyheptanoate\). To observe its market prospects, it is necessary to observe from many sources.

This product may have unique potential in the field of pharmaceutical and chemical industry. As far as medicine is concerned, its molecular structure is exquisite, or it can contact specific biological targets, and it has a chance of survival in disease treatment. If it can accurately act on the relevant physiological mechanisms, or it can become a new type of therapeutic agent, it may bring good news to the patient.

In the chemical industry, it may be used as a synthetic intermediate. Based on it, other high-value compounds may be derived, expanding the scope of chemical products, and adding new branches to the industry.

However, its market road is not smooth. The cost of research and development is the main obstacle. From molecular design to experimental verification, it requires a lot of money, which cannot be supported without strong financial resources. Furthermore, regulations and regulations are becoming increasingly stringent, and in order to make its compliance listed, it must go through many inspections, which is time-consuming and laborious.

Looking at the market competition, similar or similar products may already be numerous. If you want to stand out, you need to have unique advantages in terms of efficacy, cost and safety.

To sum up,\ ((3R, 5R) \) -tert-butyl\ (7- [2- (4-fluorophenyl) -5 -isopropyl-3-phenyl-4- (phenylaminoyl) -1H -pyrrole-1-yl] -3,5 -dihydroxyheptanoate\) The market prospect is like a flower in the fog. Although it has the hope of blooming, it needs to break through many thorns before it can see the light.