3 Trifluoromethyl Cinnamic Acid
Fluorine Difluoride Fluorobenzene Fluorobenzyl Trifluorotoluene
3-(trifluoromethyl)cinnamic acid
Chemical Formula C10H7F3O2
Molar Mass 216.16 g/mol
Appearance White to off - white solid
Melting Point 169 - 172 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, methanol, dichloromethane
Pka Value Around 4.3 (estimation for carboxylic acid group)
Density Approx. 1.38 g/cm³
Chemical Formula C10H7F3O2
Molar Mass 216.16 g/mol
Appearance White to off - white solid
Melting Point 158 - 162 °C
Solubility In Water Low solubility in water
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, methanol, dichloromethane
Pka Value Typically around 4 - 5 (weakly acidic)
Name 3-(trifluoromethyl)cinnamic acid
Molecular Formula C10H7F3O2
Molecular Weight 216.16
Appearance White to off - white solid
Melting Point 193 - 196 °C
Boiling Point 307.2 °C at 760 mmHg
Density 1.364 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in ethanol, DMSO, etc.
Pka 3.97
Flash Point 139.6 °C
Chemical Formula C10H7F3O2
Molar Mass 216.16 g/mol
Appearance White to off - white solid
Melting Point 160 - 163 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
FAQ

What is the main use of 3- (trifluoromethyl) cinnamic acid?

Tris (triethylamino) phosphocarboxylic acid is widely used. In the field of medicine, it can be a key material for synthesizing wonderful medicines. It has special chemical properties and can react ingeniously with other substances to form a unique molecular structure. This framework is used in the mechanism of action of drugs, or for the effect of increasing drugs, or for guiding drugs to specific places, so that the power of drugs can be improved and the disease can be saved.

In the field of agrochemical, it also has its traces. It can be the cornerstone of creating high-efficiency pesticides. With its properties, it may be able to make insect-proof and seedling-protecting agents, so that agricultural plants can be protected from pests and insects, to protect the abundance of five grains, and to help the food needs of the common people.

In the field of material science, it also develops its growth. Or to help develop new materials with specific properties, such as in the process of polymer polymerization, add this agent, or change the mechanical properties and stability of the material, so that the material is suitable for all kinds of foreign environments, in aviation, electronics and other industries to emit light and heat, and promote the take-off of science and technology.

In the field of catalysis, tris (triethylamino) phosphocarboxylic acid can be an efficient catalyst. It promotes all kinds of reactions to speed up, reduce energy consumption, yield, reduce costs and increase efficiency in the flow of chemical production, and promote the prosperity of industry. Its use in various industries is like a starry night, paving the way for the development of human beings and opening up new possibilities.

What are the physical properties of 3- (trifluoromethyl) cinnamic acid?

The material of tri (triethylamino) propylsilicate is transparent in color, and has fluidity under normal conditions. Its density is between 0.94 and 0.96g/cm ³, which is slightly different from water. If it is in water, it can float on water.

The boiling temperature of this material is high, 240 to 250 ° C. This characteristic makes it low in general conditions. The evaporation rate is very small, which means that under normal conditions, its self-liquid solution is not good.

In terms of solubility, it can be soluble in many soluble solutions, such as ethanol, acetone, toluene, etc. In this solution, it can disperse and form a fixed solution. However, its solubility in water is limited, and it is easy to produce hydrolysis reactions in water. This hydrolysis reaction causes its molecules to be changed, resulting in the change of silicic acid and amines.

Its viscosity is 5-10 mPa · s, and the viscosity of this degree is good for its cloth properties. If applied to the surface of the material, it can spread evenly, forming a thin and thin film.

In addition, the refractive index of this material is 1.42-1.44, and the light passes through the material. The degree of deflection varies. This property is applicable to the use of optical materials, or it is not. Moreover, the physical properties of tris (triethylamino) propylsilica are very high, making it suitable for exploration in many fields such as chemical industry and materials.

What are the chemical properties of 3- (trifluoromethyl) cinnamic acid?

Tris (triethyl) acetylsalicylic acid is an organic compound. It has many chemical properties, let me tell you one by one.

Looking at its solubility, this compound is quite soluble in organic solvents, such as ethanol and ether. Due to the fact that the molecular structure contains organophilic groups, it has a good interaction with organic solvents, just like the fusion of fish and water, and can be affinity with each other, so it has good solubility in such solvents.

In terms of stability, under general conditions, tris (triethyl) acetylsalicylic acid is still stable. However, in case of high temperature, strong acid or strong alkali environment, it is difficult to maintain stability. When the temperature is high, the internal energy of the molecule increases, and the chemical bonds of the structure are easily affected, or the decomposition reaction is caused. The strong acid and alkali can catalyze the hydrolysis reaction, causing the molecular structure to be damaged. This building is still in the event of a violent storm. Although it is usually strong, it is also at risk of collapse under severe conditions.

As for the reactivity, in this compound, the structure where the acetyl group is connected to the benzene ring changes the electron cloud density of the benzene ring, which in turn affects its reactivity. In the electrophilic substitution reaction, the benzene ring is more susceptible to attack by electrophilic reagents. Due to the electron-absorbing effect of the acetyl group, the density of the adjacent and para-potential electron clouds of the benzene ring is relatively reduced, and the density of the meta-potential electron cloud is relatively increased, This is like the advantage of the military, the difference in electron cloud density at different locations determines the direction of the reaction.

Because of its carboxyl group, it can neutralize with the base to form the corresponding carboxylate and water. This is a typical reaction of carboxylic groups, just like acid and base meet, naturally neutralize to achieve equilibrium.

The chemical properties of tris (triethyl) acetylsalicylic acid are determined by its unique molecular structure and exhibit different reaction characteristics under different conditions. This is the wonder of chemistry.

What are the preparation methods of 3- (trifluoromethyl) cinnamic acid?

To make triethylmalonic acid, there are several ancient methods as follows.

First, start with diethyl malonate. Take diethyl malonate, make it meet with sodium ethanol, sodium ethanol, strong alkalinity, can take the hydrogen of methylene in diethyl malonate and form carbon negative ions. Next, add triethyl halogen, carbon negative ions nucleophilic attack the carbon of the halogen, and the halogen ions leave to obtain diethyl triethylmalonate. After hydrolyzing the ester with dilute acid and decarboxylating it by heating, triethylmalonate is obtained. The reaction formula is roughly as follows:
diethyl malonate + sodium ethyl alcohol → [carbon negative ion intermediate]
[carbon negative ion intermediate] + triethyl halogen → diethyl triethylmalonate
diethyl triethylmalonate + dilute acid, heating → triethylmalonate + carbon dioxide

Second, ethyl acetoacetate is used as the group. First, ethyl acetoacetate interacts with sodium alcohol to generate carbon negative ions. Then reacts with triethyl halogenated hydrocarbons to introduce triethyl groups. After treatment with alkali solution, the ester group is hydrolyzed, re-acidified, and decarboxylated by heating, and triethylmalonate can also be obtained. The reaction process is as follows:
ethyl acetoacetate + sodium alcohol → [carbon negative ion intermediate]
[carbon negative ion intermediate] + triethyl halogenated hydrocarbon → [substituted product]
[substituted product] + alkali solution, acidification, heating → triethylmalonic acid + carbon dioxide

third, with halogenated acid as the starting material. If there is a suitable halogenated acid, such as a halogenated acid containing triethyl substitution, it can first react with sodium cyanide, and the halogen atom is replaced by a cyano group. After the cyanide is hydrolyzed to a carboxyl group, triethylmalonic acid can be obtained. The reaction steps are:
halogenated acid + sodium cyanide → [cyano substituted product]
[cyano substituted product] + water, acid or base catalyzed → triethylmalonic acid.

All methods have advantages and disadvantages, and must be selected according to the actual raw materials and conditions in order to obtain this compound efficiently.

What is the price range of 3- (trifluoromethyl) cinnamic acid in the market?

In today's market, the price of triethyllactic acid is about ten to thirty pennies per catty. The change in its price often depends on supply and demand and production conditions. If the market is prosperous and produces less, the price will increase; if the supply is large and the demand is slow, the price will decrease.

I have heard of Zhu Jia people. At the beginning of the year, the weather was cold, and the production of this product was rare. The price of ointment and color matching required by hospitals and dyeing workshops was as high as thirty pennies per catty. When the spring is deep and the air is warm, there are more and more producers, and the market has a stock of goods, and other goods can be replaced. Those who ask for it are reduced, and the price is then reduced to about ten pennies per catty.

There are also foreign merchants coming from afar, and if the volume is large, the price will also be disturbed by it. When the production from afar is covered and shipped to this state, the market will increase, and the price will often fall due to it. And the local producers also strive to win by their skills. If there are new technologies to improve the quality of the production, the price will also move. Or reduce to compete for the market, or insure the price and seek a big profit, it is all up to them.

From this point of view, the price of triethyllactic acid in the market is not fixed, and it often changes with time and events. The contract of ten to thirty texts is only for the world to see.