Chemical Formula | C42H33F3O2 |
Molecular Weight | 614.705 g/mol |
Appearance | Solid (predicted) |
Boiling Point | Estimated high due to large molecular size |
Melting Point | Estimated to be relatively high |
Solubility In Water | Low (hydrophobic due to large aromatic groups) |
Solubility In Organic Solvents | Good in non - polar solvents like toluene |
Density | Estimated based on similar aromatic compounds |
Pka | Related to phenolic - OH groups, around 9 - 10 for phenolic acidity |
Uv Vis Absorption | Absorption in the UV region due to conjugated aromatic systems |
Ir Absorption | Characteristic peaks for C - H, C = C, O - H, C - F vibrations |
Chemical Formula | C42H33F3O2 |
Molecular Weight | 626.70 |
Physical State | Solid (predicted) |
Melting Point | Unknown |
Boiling Point | Unknown |
Solubility In Water | Low (due to non - polar nature of large phenyl groups and hydrophobic trifluoromethyl group) |
Logp | High (lipophilic, due to multiple phenyl rings and trifluoromethyl group) |
Appearance | White to off - white solid (predicted) |
Density | Unknown |
Vapor Pressure | Very low (as a solid with large non - volatile structure) |
Chemical Formula | C41H31F3O2 |
Molecular Weight | 608.68 g/mol |
Appearance | Solid (predicted) |
Physical State At Room Temp | Solid |
Solubility In Water | Low (predicted, due to non - polar nature of large aromatic groups) |
Boiling Point | Predicted to be high due to large molecular size and intermolecular forces |
Melting Point | High (due to strong intermolecular forces in the solid) |
Vapor Pressure | Low (large non - volatile molecule) |
Logp | High (hydrophobic, lipophilic due to phenyl groups) |
Polar Surface Area | 37.3 Ų (estimated from structure for hydroxyl groups) |
Chemical Formula | C42H33F3O2 |
Molecular Weight | 620.70 |
Physical State | Solid (predicted) |
Appearance | White to off - white powder (estimated) |
Solubility In Water | Low solubility (predicted due to large non - polar structure) |
Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform (predicted based on structure) |
Logp | High (hydrophobic, predicted based on large aromatic content and trifluoromethyl group) |
What is the chemical structure of 3-phenyl-5- (1,1,1-trifluoro-2- {6-hydroxy-5-phenyl- [1,1 '-biphenyl] -3-yl} propan-2-yl) - [1,1' -biphenyl] -2-ol?
This is a rather complex organic compound with a long name and many substituents. According to the organic chemistry nomenclature, "3-phenyl-5- (1,1,1-trifluoro-2 - {6-hydroxy-5-phenyl - [1,1 '-biphenyl] - 3-yl} propan - 2 - yl) - [1,1' -biphenyl] - 2 - ol" involves the following structures:
"[1,1 '-biphenyl]" is a biphenyl structure, formed by two phenyl rings connected by a single bond. On top of the biphenyl structure, 2-ol shows a hydroxyl (-OH) substitution at position 2 of one of the benzene rings of the biphenyl; 3-phenyl shows a phenyl (-C H) substitution at position 3 of the same benzene ring.
And "5 - (1,1,1 - trifluoro - 2 - {6 - hydroxy - 5 - phenyl - [1,1 '-biphenyl] - 3 - yl} propan - 2 - yl) " This part is connected to a complex side chain at position 5 of the other benzene ring of the biphenyl. In this side chain, "1,1,1 - trifluoro - 2 - {6 - hydroxy - 5 - phenyl - [1,1 '-biphenyl] - 3 - yl} propan - 2 - yl", its main chain is propane structure (propan), there are three fluorine atoms (1,1,1 - trifluoro) at position 1, and position 2 is connected to a group, which in turn contains a "6 - hydroxy - 5 - phenyl - [1,1' -biphenyl] - 3 - yl" structure, that is, another biphenyl structure, the 5th position of a phenyl ring in this biphenyl structure There is phenyl substitution and hydroxyl substitution at position 6, and the biphenyl structure is connected to the main chain through position 3.
In summary, the chemical structure of the compound is based on biphenyl as the core, and is connected to phenyl, hydroxyl, and complex side chains containing fluorine and another biphenyl substituent at different positions. This structure combines the aromatic properties of biphenyl, the reactivity of hydroxyl groups, and the special properties endowed by fluorine-containing groups, and may have unique applications in the fields of organic synthesis and materials science.
What are the main uses of 3-phenyl-5- (1,1,1-trifluoro-2- {6-hydroxy-5-phenyl- [1,1 '-biphenyl] -3-yl} propan-2-yl) - [1,1' -biphenyl] -2-ol?
3 - phenyl - 5 - (1,1,1 - trifluoro - 2 - {6 - hydroxy - 5 - phenyl - [1,1 '-biphenyl] - 3 - yl} propan - 2 - yl) - [1,1' -biphenyl] - 2 - ol, this compound is a complex organic molecule. It has a wide range of main uses and is often used as a key intermediate in the field of organic synthesis. Due to its unique structure, containing polyphenyl rings and special functional groups, it can use chemical reactions to construct a variety of complex organic compounds, laying the foundation for the synthesis of new drugs and materials.
In the field of drug research and development, or with potential biological activity. It contains hydroxyl, phenyl and other groups that can interact with targets in vivo, such as binding to specific proteins and enzymes, or affecting cell signaling pathways, or regulating physiological processes, and is expected to be developed as a drug for the treatment of specific diseases.
In the field of materials science, due to the fluorine atom, compounds are endowed with unique physical and chemical properties, such as enhanced hydrophobicity and thermal stability. Or can be used to prepare high-performance materials, such as special coating materials, with their hydrophobicity and stability, to improve the corrosion resistance and wear resistance of materials; or used to prepare optoelectronic materials, using their structural characteristics to achieve specific photoelectric conversion functions.
This compound has important potential applications in the fields of organic synthesis, drug development, and materials science, providing opportunities for researchers to explore new substances and develop new technologies.
What is the synthesis method of 3-phenyl-5- (1,1,1-trifluoro-2- {6-hydroxy-5-phenyl- [1,1 '-biphenyl] -3-yl} propan-2-yl) - [1,1' -biphenyl] -2-ol?
The synthesis of 3-phenyl-5 - (1,1,1-trifluoro-2 - {6-hydroxy-5-phenyl-[ 1,1 '-biphenyl] -3-yl} propyl-2-yl) - [1,1' -biphenyl] - 2 - alcohol is an important matter in the field of chemical synthesis. To synthesize this compound, follow the following steps.
First, the selection of raw materials is the key. Compounds containing structural fragments such as phenyl, biphenyl, and trifluoromethyl need to be prepared. Such raw materials may be commercially available or need to be prepared by themselves. For example, common halogenated aromatics, phenolic compounds, and halogenated alkanes containing trifluoromethyl groups are used as starting materials.
Second, the design of the reaction path is critical to success or failure. Transition metal-catalyzed coupling reactions can be used, such as palladium-catalyzed Suzuki coupling reaction. In this reaction, an aromatic compound containing borate esters or boric acids and a halogenated aryl compound are heated in an organic solvent in the presence of a palladium catalyst, a base, and suitable ligands to form a biphenyl structure. For example, with suitable borate-containing biphenyl derivatives and halogenated phenyl compounds, under the catalysis of [Pd (PPh) ], potassium carbonate is a base, toluene is a solvent, and heating is refluxed to promote the formation of aryl-aryl bonds.
Furthermore, the introduction and protection of hydroxyl groups also need to be cautious. For the hydroxyl groups in the target product, it may be necessary to protect them during the reaction to avoid unnecessary side reactions in subsequent reactions. Commonly used hydroxyl protecting groups such as silicon ethers, benzyl groups, etc. After the main structure is constructed, the protecting groups are removed under suitable conditions to obtain the required hydroxyl groups.
Again, the introduction of trifluoromethyl substituents. Trifluoromethyl can be introduced into the molecule by a nucleophilic substitution reaction in which a nucleophilic reagent containing trifluoromethyl reacts with the corresponding halogenated hydrocarbon or sulfonate. For example, the introduction of trifluoromethyl is achieved by reacting a trifluoromethylating reagent such as sodium trifluoromethylsulfonic acid with a halogenated intermediate product in the presence of a suitable base and solvent.
At the end, after the reaction is completed, it needs to go through the separation and purification steps. Column chromatography is often used to separate and purify the target product from the reaction mixture with a suitable eluent, and then obtain high-purity 3-phenyl-5- (1,1,1-trifluoro-2 - {6-hydroxy-5-phenyl- [1,1 '-biphenyl] - 3-yl} propyl-2-yl) - [1,1' -biphenyl] - 2-ol. This synthesis method requires fine operation and strict control of reaction conditions to achieve the synthesis of the target product smoothly.
What are the physical properties of 3-phenyl-5- (1,1,1-trifluoro-2- {6-hydroxy-5-phenyl- [1,1 '-biphenyl] -3-yl} propan-2-yl) - [1,1' -biphenyl] -2-ol?
This is a complex organic compound named 3-phenyl-5- (1,1,1-trifluoro-2-{ 6-hydroxy-5-phenyl-[ 1,1 '-biphenyl] -3-yl} propyl-2-yl) - [1,1' -biphenyl] -2-ol. Its physical properties are quite critical and are related to many applications of this compound.
From its appearance, it is often in a solid state. Due to the strong intermolecular forces, it exists in a solid state at room temperature and pressure. As for the color, or white to light yellow, this is related to the molecular structure and purity. If it contains impurities, the color may change.
Melting point is also an important physical property. Due to the complex molecular structure, there are a large number of aromatic rings and hydrogen bonding check points, and its melting point is relatively high. However, the specific value varies depending on the measurement method and purity, and usually needs to be determined by precise experiments.
In terms of solubility, the compound contains a large number of hydrophobic aromatic ring structures and has very low solubility in water. However, in organic solvents such as dichloromethane, chloroform, toluene, etc., it has good solubility by virtue of the van der Waals force between the aromatic ring and the organic solvent molecules.
In addition, its density is also affected by the molecular structure. Due to the presence of fluorine atoms in the molecule, the relative atomic mass is relatively large and the structure is compact, so the density may be higher than that of common organic solvents.
The physical properties of this compound, such as appearance, melting point, solubility, density, etc., are of great significance in the fields of organic synthesis and materials science, and have guiding value for its separation, purification and application.
What is the market outlook for 3-phenyl-5- (1,1,1-trifluoro-2- {6-hydroxy-5-phenyl- [1,1 '-biphenyl] -3-yl} propan-2-yl) - [1,1' -biphenyl] -2-ol?
Guanfu 3 - phenyl - 5 - (1,1,1 - trifluoro - 2 - {6 - hydroxy - 5 - phenyl - [1,1 '-biphenyl] - 3 - yl} propan - 2 - yl) - [1,1' -biphenyl] - 2 - ol This product can be viewed from multiple perspectives in terms of market prospects.
From the perspective of scientific research, such compounds often have unique chemical structures and potential biological activities. The combination of fluorine-containing groups and polybiphenyl structures may exhibit specific physical and chemical properties, and can be a hotspot of research in various scientific research branches such as medicinal chemistry and materials science. Researchers are always looking for compounds with innovative properties and functions. Such novel structures may trigger a new wave of research upsurge, giving rise to many new theories and methods, and expanding paths for subsequent research.
As for the pharmaceutical market, its prospects are also promising. If this compound is confirmed to have significant biological activities, such as antibacterial, anti-inflammatory, and anti-tumor, after in-depth pharmacological research, it will definitely provide a key precursor for the development of new drugs. In today's pharmaceutical industry, there is a strong demand for high-efficiency and low-toxicity new drugs. If this compound can be developed into a drug, it may gain a place in the highly competitive pharmaceutical market, bringing good news to patients and creating huge profits for pharmaceutical companies.
In the field of materials, due to its special structure, it may endow materials with unique properties. For example, in optical materials, it may change the properties of optical refraction and fluorescence of materials; in polymer materials, it may affect the thermal stability and mechanical properties of materials. With the rapid development of materials science, the demand for materials with special properties is increasing day by day. If there is a breakthrough in this, it will open up a wide range of applications.
But it is also necessary to be clear that the road of its activity marketing may not be smooth. The complexity of the synthesis process, cost control, and regulatory policies are all previous challenges. Only by overcoming various difficulties can this compound shine in the market and truly realize its value.