Chemical Formula | C7H3Cl2F3 |
Molar Mass | 215.00 g/mol |
Appearance | Colorless liquid |
Boiling Point | 164 - 166 °C |
Melting Point | −37 °C |
Density | 1.492 g/cm³ |
Vapor Pressure | 1.33 hPa (20 °C) |
Solubility In Water | Insoluble |
Flash Point | 57 °C |
Refractive Index | 1.4525 (20 °C) |
Chemical Formula | C7H3Cl2F3 |
Molar Mass | 215.00 g/mol |
Appearance | Colorless to light yellow liquid |
Boiling Point | 174 - 176 °C |
Density | 1.48 g/cm³ |
Solubility | Insoluble in water, soluble in organic solvents |
Flash Point | 66 °C |
Refractive Index | 1.444 |
Chemical Formula | C7H3Cl2F3 |
Molar Mass | 215.00 g/mol |
Appearance | Colorless to light yellow liquid |
Boiling Point | 174 - 176 °C |
Melting Point | -45 °C |
Density | 1.489 g/cm³ at 20 °C |
Vapor Pressure | 1.33 hPa at 25 °C |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in common organic solvents |
Flash Point | 63 °C |
Refractive Index | 1.451 |
Chemical Formula | C7H3Cl2F3 |
Molar Mass | 215.00 g/mol |
Appearance | Colorless to light yellow liquid |
Boiling Point | 171 - 172 °C |
Density | 1.495 g/cm³ |
Solubility | Insoluble in water, soluble in organic solvents |
Flash Point | 60 °C |
Refractive Index | 1.445 |
What are the main uses of -α,α,α-
3,4-Difluoro - α,α,α - trifluorotoluene is one of the organic compounds. Its main uses cover a wide range of fields.
In the field of medicinal chemistry, this compound is often used as a key intermediate. Due to the unique electronic properties and spatial effects of fluorine atoms, the physical, chemical and biological activities of compounds can be significantly changed after the introduction of molecular structures. Through its participation in reactions, many new drugs with high biological activity, strong specificity and good pharmacokinetic properties can be created. For example, it can be used to synthesize inhibitors targeting specific disease targets, providing an important structural basis for the development of new drugs, and helping to overcome difficult diseases such as tumors and cardiovascular diseases.
In the field of materials science, 3,4-difluoro - α,α,α - trifluorotoluene also plays an important role. Due to its fluorine-containing structure, the material has unique properties, such as low surface energy, high chemical stability and excellent electrical properties. Therefore, it is often used to prepare high-performance polymer materials, which are widely used in aerospace, electronics and other fields. In the aerospace field, it can be used to manufacture lightweight components with excellent weather resistance and chemical stability; in the electronic and electrical fields, it can be used as a raw material for the manufacture of high-performance insulating materials or display materials to improve the performance and stability of products.
In the field of pesticide chemistry, this compound can be used to create new high-efficiency pesticides. The introduction of fluorine atoms can enhance the toxic effect and selectivity of pesticides to pests, while reducing the impact on the environment and the toxicity to non-target organisms. With its special structure, it can develop specific pesticides for specific pests or diseases, improve the yield and quality of crops, and ensure the sustainable development of agriculture.
In summary, 3,4-difluoro - α,α,α - trifluorotoluene plays an indispensable role in many fields such as medicine, materials, pesticides, etc., and has made great contributions to promoting technological progress and development in various fields.
What are the physical properties of 3,4-dichloro -α,α,α- trifluorotoluene
3,4-Difluoro -α,α,α - trifluorotoluene is one of the organic compounds. Its physical properties are unique and closely related to many fields of chemical industry.
When it comes to the properties of this substance, under room temperature and pressure, 3,4-difluoro -α,α,α - trifluorotoluene are mostly colorless and transparent liquids. It looks clear, like still water, without any impurities. Although its smell is not pungent and intolerable, it also has a unique fragrance. The unusual smell is comparable. If you smell it carefully, you can feel the unique smell of chemical raw materials.
As for the boiling point, this substance is about a specific temperature range, this temperature is the critical node of its transition from liquid to gaseous state. The value of the boiling point is determined by science, and it is about a certain temperature range. At this temperature, the state of matter changes according to the usual way of physics. This boiling point characteristic is crucial in the separation and purification process of chemical production. According to its boiling point, it can be separated from the mixture by distillation and other methods to achieve the purpose of purification.
The melting point is the temperature limit for the substance to change from solid to liquid. The melting point of 3,4-difluoro -α,α,α - trifluorotoluene also has its fixed number and is in a certain low temperature range. The existence of the melting point determines its shape under different ambient temperatures. At low temperatures, or in the form of a solid state, it is as stable as a rock; when the temperature gradually rises, it melts into a liquid state.
Furthermore, its density is also an important physical property. Each unit volume of 3,4-difluoro -α,α,α - trifluorotoluene has its specific mass value. This density characteristic is indispensable for material measurement and mixing in many chemical processes. According to its density, the amount of material required can be accurately calculated to ensure the accurate progress of the reaction.
In terms of solubility, 3,4-difluoro -α,α,α - trifluorotoluene exhibits a unique solubility in organic solvents. In some organic solvents, such as aromatic hydrocarbons and halogenated hydrocarbon solvents, it can be well miscible, just like fish water. However, in water, the solubility is very small, and the two are almost distinct. This difference in solubility provides an important basis for chemical extraction and reaction medium selection.
What are the chemical properties of -α,α,α-
3,4-Difluoro - α,α,α - trifluorotoluene, is a kind of organic compound. Its chemical properties are particularly interesting, let me explain in detail.
This compound has the characteristics of halogenated aromatics. The introduction of fluorine atoms makes its properties different from ordinary aromatics. The electronegativity of fluorine is extremely high, resulting in a unique molecular electron cloud distribution. Therefore, its chemical activity is also different from that of common aromatic hydrocarbon derivatives.
In terms of reactivity, due to the substitution of fluorine atoms on its aromatic ring, the density of the aromatic ring electron cloud decreases. In this case, the electrophilic substitution reaction is slightly more difficult than benzene. However, under suitable conditions, electrophilic substitution can still occur, and the localization effect of fluorine atoms is also unique. The ratio of ortho-and para-substitution products is affected by the electronic effect of fluorine atoms and the space effect.
And because it contains multiple fluorine atoms, the stability of the compound is quite high. The fluorine-carbon bond energy is large, which makes the molecular structure stable, and it is not easy to decompose or other violent reactions under normal conditions. This stability is extremely valuable in many fields, such as the preparation of highly stable materials or as an intermediate for special reactions.
At the same time, the solubility of the compound also has characteristics. Due to the presence of fluorine atoms, its solubility in organic solvents is different from that of ordinary aromatic hydrocarbon derivatives. Some polar organic solvents have good solubility to them, but the solubility in water is extremely low, which is due to the change of the overall polarity of the molecule by the influence of fluorine atoms.
When participating in chemical reactions, in addition to electrophilic substitution, reactions such as reduction and oxidation can also be carried out. However, such reactions require specific reagents and conditions to achieve the desired product. And during the reaction process, the presence of fluorine atoms often affects the reaction path and rate, resulting in a unique reaction mechanism.
The chemical properties of 3,4-difluoro - α,α,α - trifluorotoluene are determined by their unique molecular structure, and show important application potential in organic synthesis, materials science and other fields.
What is the preparation method of 3,4-dichloro -α,α,α- trifluorotoluene
To prepare 3% 2C4 -difluoro - α,α,α - trifluorotoluene, the method is as follows:
First of all, all kinds of materials need to be prepared, and the reagents and instruments used must be clean and accurate. The corresponding fluorine-containing halides are often used as starting materials. The selection of this halogen needs to meet the structural requirements of the reaction mechanism and the target product.
In a clean and dry reaction vessel, add the starting material and an appropriate amount of catalyst in a certain proportion. The choice of catalyst is very critical, which can effectively reduce the activation energy of the reaction and accelerate the reaction process. For example, some specific metal salts or organometallic complexes may become excellent catalysts for this reaction, but the specific choice depends on the characteristics of the raw materials and the reaction conditions.
Next, fluorinated reagents are slowly introduced into the reaction system. The rate of addition of fluorinated reagents depends on the stability of the reaction and the purity of the product. Too fast or too slow may lead to the occurrence of side reactions, which in turn affect the yield of the product.
During the reaction process, precise temperature control is required. Reactions at different stages have different temperature requirements. Generally speaking, the temperature can be maintained at a specific low temperature range in the initial stage, so that the raw materials and reagents can be fully mixed and the initial reaction can be carried out. Then, according to the reaction process, the temperature is gradually increased, which prompts the reaction to proceed in the direction of generating the target product. Temperature control is often achieved with the help of precision temperature control equipment.
At the same time, the pressure of the reaction system cannot be ignored. According to the reaction characteristics, the reaction may be carried out at normal pressure or under specific pressure conditions. By adjusting the degree of airtightness of the reaction vessel and the amount of gas entering and leaving, a suitable pressure environment can be maintained.
After the reaction is completed, a series of post-processing steps are required. The reaction mixture is extracted with an appropriate solvent to transfer the target product to a specific phase. Then the impurities are removed through separation, washing, drying and other steps. Finally, the purified product of 3% 2C4-difluoro - α,α,α - trifluorotoluene is obtained by distillation, recrystallization and other purification methods. Throughout the process, it is necessary to adhere to the operating procedures and precisely control the parameters of each link in order to achieve the desired results.
What are the precautions for the use of 3,4-dichlorotoluene -α,α,α-
3% 2C4- - α,α,α - trifluorotoluene is a commonly used raw material in organic synthesis. In the process of use, many precautions must not be ignored.
First safety protection. Because of its certain toxicity and irritation, when operating, it is necessary to wear protective clothing, gloves, goggles and gas masks to prevent skin contact and inhalation. Because of its volatile vapor or respiratory irritation and poisoning, operate in a well-ventilated environment or in a fume hood to ensure air circulation and disperse harmful vapors in time.
Furthermore, pay attention to storage conditions. Store in a cool, dry and ventilated place, away from fire and heat sources. Because it is flammable, it can burn and explode in case of open flame or hot topic. And it should be stored separately from oxidants, alkalis, etc., and should not be mixed with storage to prevent violent reactions.
When using, it is also crucial to accurately control the dosage. According to the specific reaction requirements, accurately measure to avoid side reactions caused by excessive dosage, or reactions difficult to achieve the desired effect due to insufficient dosage. At the same time, the operation process needs to strictly follow the operating procedures, add slowly, and prevent dangerous conditions such as flushing and boiling caused by rapid addition.
In addition, the container after use must not be discarded at will, and should be properly handled in accordance with relevant regulations to prevent pollution to the environment. If there is a leak, it is necessary to immediately isolate the leaking contaminated area and restrict personnel from entering and leaving. Emergency personnel should wear full masks, wear anti-virus clothing, and collect it in a dry, clean, covered container with a clean shovel and transfer it to a safe place.
In short, when using 3% 2C4-dichloro- - α,α,α - trifluorotoluene, safety is the key, and strict operation in accordance with regulations can ensure personal safety and smooth progress of experiments and production.