What is the chemical structure of (2S) -6-fluoro-3, 4-dihydro-2H-1-Benzopyran-2-carboxylic acid?

(2S) -6-fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid, which is an organic compound. In its chemical structure, the core is a benzopyran ring, which is formed by fusing a benzene ring with a pyran ring.

The benzopyran ring is connected with a carboxyl group (-COOH) at the second position. This carboxyl group gives the compound certain acidic properties and can participate in many acid-base reactions and esterification reactions. Above the 6-position, there are fluorine atoms. Due to their large electronegativity, fluorine atoms will affect the electron cloud distribution and spatial structure of the molecule, which in turn affects the physical and chemical properties of the compound, such as its polarity and stability. And the 3,4-position is the dihydrogen structure, that is, the 3,4-position double bond of the pyran ring is hydrogenated. This structural change will also affect the conjugate system of the molecule, thus affecting its spectral properties and chemical reactivity. The structural characteristics of this compound determine that it may have specific biological activities. In the field of organic synthesis, it can often be used as a key intermediate for the construction of more complex organic molecules, providing important starting materials for the development of new drugs, the preparation of functional materials, and many other fields. The uniqueness of its structure also provides a broad space for exploring novel chemical reaction pathways and properties.

What are the physical properties of (2S) -6-fluoro-3, 4-dihydro-2H-1-Benzopyran-2-carboxylic acid?

(2S) -6-fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid is a kind of organic compound. Its physical properties are quite important and are related to many applications in chemistry and related fields.

When it comes to appearance, this compound is often in a white to off-white solid form. This feature is useful for identifying and preliminarily judging its purity and characteristics. Looking at the uniformity of its color and morphology, it can be seen a little bit about its quality.

Melting point is also a key physical property. The melting point of (2S) -6-fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid is within a specific range. Accurate determination of the melting point can not only identify the compound, but also detect its purity. If impurities are mixed, the melting point often deviates, or the melting point range is widened.

In terms of solubility, it varies from common organic solvents. In some polar organic solvents, such as methanol and ethanol, it may have a certain solubility. This property facilitates the selection of suitable solvents in chemical reactions, so that the reaction can proceed smoothly. In non-polar solvents, its solubility may be very low, which is also one of its characteristics.

In addition, density is also a consideration of physical properties. Although the determination of density may be more complex than other properties, it is essential to understand the behavior of the compound under specific conditions. Knowing the density can provide key parameters when it comes to solution preparation, separation and purification.

In summary, the physical properties of (2S) -6-fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acids, such as appearance, melting point, solubility and density, are of great significance to their research, application and quality control, and researchers can carry out relevant chemical operations and experiments.

What are the main uses of (2S) -6-fluoro-3, 4-dihydro-2H-1-Benzopyran-2-carboxylic acid?

(2S) -6-fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid has a wide range of uses. In the field of medicine, it is a key intermediate for the preparation of many specific drugs. Due to its unique chemical structure, it can precisely fit with specific biological targets, helping to develop innovative drugs with high efficiency and low toxicity, and plays an important role in the creation of anti-cardiovascular, anti-tumor and neurological diseases drugs.

In the field of organic synthesis, it is like a cornerstone, providing the possibility to construct complex organic molecular structures. Through various chemical reactions, it can be ingeniously transformed to derive a series of compounds with diverse structures, which greatly expands the boundaries of organic synthesis chemistry and paves the way for the exploration of new materials and new functional molecules.

In the field of materials science, (2S) -6-fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid also has outstanding performance. It can be incorporated into the material system through special processes to endow materials with better stability, unique optical or electrical properties, etc., contributing to the development of high-performance materials and promoting the development of electronic and optical materials and other industries.

Overall, this compound plays a pivotal role in many fields such as medicine, organic synthesis, and materials science. It is like an important key to open the door to scientific progress, leading various fields to new heights.

What are the synthesis methods of (2S) -6-fluoro-3, 4-dihydro-2H-1-Benzopyran-2-carboxylic acid?

The synthesis of (2S) -6-fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acids is a key research direction in the field of organic synthesis. This compound has potential application value in fields such as medicinal chemistry, so it is of great significance to seek an efficient synthesis path.

One method can be started from suitable aromatic starting materials. For example, the prototype of benzopyran ring is constructed by introducing a suitable hydrocarbon group at the phenol hydroxyl group through etherification reaction with a specific substituted phenol compound as the group. In this process, the etherification reagents and reaction conditions should be carefully selected, such as halogenated hydrocarbons as etherification agents, in an alkaline environment, and reacted at moderate temperatures to improve the yield and selectivity of the reaction.

Then, the hydrogenation reaction is carried out for the benzopyran ring to form a 3,4-dihydro-2H-1-benzopyran structure. Suitable catalysts, such as palladium-carbon catalysts, can be used to react in a hydrogen atmosphere. This step requires attention to control the hydrogen pressure, reaction temperature and time to ensure the smooth progress of the hydrogenation reaction and avoid excessive hydrogenation or other side reactions.

Furthermore, carboxyl functional groups are introduced. The benzopyran derivative containing halogen atoms can be prepared by the Grignard reagent method, then reacted with magnesium to make Grignard reagent, and then reacted with carbon dioxide to obtain the target (2S) -6-fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid after hydrolysis. In this process, the preparation conditions of Grignard reagents are strict, and an anhydrous and oxygen-free environment is required to ensure the success of the reaction.

Or, a synthetic strategy induced by chiral additives can be tried. The chiral source was selected to combine with the starting material, and the chiral auxiliary agent was used to guide the formation of the target chiral configuration in the key reaction steps. After the reaction is completed, the chiral auxiliary agent is properly removed to obtain high-purity (2S) -6-fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid.

The above synthesis methods have their own advantages and disadvantages. In practical applications, it is necessary to comprehensively weigh the availability of raw materials, feasibility of reaction conditions, cost considerations and other factors to choose the optimal synthesis path.

What is the market price of (2S) -6-fluoro-3, 4-dihydro-2H-1-Benzopyran-2-carboxylic acid?

What is the price of (2S) -6-fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid in the market? This question is quite complicated. The market conditions often change from time to time and are also influenced by many factors.

Looking at the past pharmaceutical market, the price of chemical raw materials was often tied to the balance between supply and demand. If the demand for this product is strong and the supply is limited, the price will rise; if the supply exceeds the demand, the price will drop. Furthermore, the difficulty of production and the simplicity of the process are also related to the cost, which in turn affects the price. If the preparation method requires complicated processes, a lot of consumables, and the cost must be high, the price in the market is not low.

However, I have checked the ancient books all over, but I have not obtained the exact current price of this thing. Or due to the variety of transactions in the market, the pricing of each company is different, and the transmission of information is not smooth from time to time. To know the exact price, you can consult the chemical raw material suppliers, or visit the professional trading platform, so that you can get a more accurate price.

Although the exact price of the current is not clear, according to the common sense in the market, it can be deduced that the price will fluctuate due to the above factors. If you want to buy and sell, it is advisable to carefully observe the market conditions and compare and choose from multiple parties to obtain the best price.