What is the chemical structure of (2S) -2-amino-6- [ (2,2,2-trifluoroacetyl) amino] hexanoic acid

(2S) -2-amino-6- [ (2,2,2-trifluoroacetyl) amino] hexanoic acid, which is a kind of organic compound. Looking at its naming, it can follow the naming rules of organic chemistry to deduce its chemical structure.

" (2S) " means that the configuration of the second carbon atom in this compound is S-type, which is related to the stereochemical structure of the molecule and has a specific orientation in spatial arrangement.

"2-amino", which is clearly shown that the second carbon atom of the molecular main chain is connected with an amino group (-NH ²). The amino group is a nitrogen-containing active group, which often makes the compound have basic and other characteristics.

"6- [ (2,2,2-trifluoroacetyl) amino]", indicating that a specific substituent is attached to the sixth carbon atom. Among them, 2,2,2-trifluoroacetyl is derived from acetyl group, and there are three fluorine atoms (CF 🥰 CO -) attached to the α-carbon of the acetyl group. This trifluoroacetyl group is connected to the amino group to form an amide bond (-CONH -), which is connected to the 6th carbon in the main chain.

"Hexanoic acid" indicates that the main chain of the compound is a six-carbon carboxylic acid, and its terminal carboxyl group (-COOH) gives the molecule acidic properties.

In summary, the chemical structure of (2S) -2-amino-6- [ (2,2,2-trifluoroacetyl) amino] hexanoic acid is: the hexacarbon chain is the main chain, the second carbon is connected with an S-type amino group, and the sixth carbon is connected with a 2,2,2-trifluoroacetyl group through an amide bond, and the chain end is a carboxyl group. The structure of the compound is shown as follows (in simplified form):

CH < CH > CH (NH < 2) CH < 2 CH (NHCOCF < 3) COOH

This structure makes the compound have the characteristics of both amino, carboxyl and fluoroamide groups, and may have specific reactivity and application value in organic synthesis, pharmaceutical chemistry and other fields.

What are the physical properties of (2S) -2-amino-6- [ (2,2,2-trifluoroacetyl) amino] hexanoic acid

(2S) -2 -Amino-6- [ (2,2,2 -trifluoroacetyl) amino] hexanoic acid, this is an organic compound. Its physical properties are quite important, related to its performance in various chemical processes and practical applications.

First, let's talk about the appearance. Usually, it appears as a white to off-white crystalline powder. This appearance makes it easy to identify and handle in many scenarios. Its color is pure and the texture is delicate, like fine white snow, showing its high purity and quality.

Melting point is also a key physical property. The melting point of this substance is in a specific range, between about [X] ° C and [X] ° C. The characteristics of the melting point are like a precise ruler, which can be used to determine its purity. If impurities exist, the melting point will often be offset, or increased, or decreased. Therefore, the determination of the melting point has become one of the important means to measure the purity of the substance.

The solubility is also not negligible. It shows different solubility characteristics in some common organic solvents. In water, it has a certain solubility. Although it is not very soluble, it can form a uniform dispersion system under moderate conditions, just like salt dissolves in water, but the degree of solubility varies. In organic solvents such as ethanol and methanol, the solubility is relatively good, and it can dissolve relatively quickly to form a uniform and transparent solution, just like sugar fused into hot water, uniform and thorough.

In addition, its density also has a specific value, which is about [X] g/cm ³. The physical quantity of density reflects the mass of the substance in a unit volume, and has important reference value in the separation and mixing of substances. It is like a hidden standard for measuring the weight of objects, which invisibly affects various operations.

To sum up, these physical properties of (2S) -2 -amino-6- [ (2,2,2 -trifluoroacetyl) amino] hexanoic acid, like its unique "chemical fingerprint", lay the foundation for its application in chemical research, drug synthesis and other fields.

What is the main use of (2S) -2-amino-6- [ (2,2,2-trifluoroacetyl) amino] hexanoic acid

(2S) -2-amino-6- [ (2,2,2-trifluoroacetyl) amino] hexanoic acid, which is an organic compound. Its main uses are quite extensive, and it is of great significance in the field of medicine. It is often used as a key intermediate in the synthesis of various drugs. Due to its special chemical structure, it can participate in the construction of complex drug molecules and help synthesize drugs with specific biological activities and pharmacological effects. For example, in the development of some antibacterial drugs, it may be used as a key fragment. After a series of chemical reactions, it is integrated into drug molecules to give the drug the ability to inhibit or kill specific bacteria.

In the field of organic synthetic chemistry, it is also an important basic raw material. Chemists can develop a rich variety of organic compounds by modifying and transforming various functional groups. Through ingenious reaction design, it can be used as a starting point to construct complex and novel organic molecules, providing new compound options for materials science, drug development and many other fields. In addition, in biochemical research, it may be used as a tool compound to explore the mechanism of some biochemical reactions in organisms. Its special structure may be able to simulate some key molecules in organisms, thus enabling researchers to gain a deeper understanding of chemical changes in life processes.

What are the synthesis methods of (2S) -2-amino-6- [ (2,2,2-trifluoroacetyl) amino] hexanoic acid

The synthesis method of (2S) -2-amino-6- [ (2,2,2-trifluoroacetyl) amino] hexanoic acid has been around for a long time, and with the changes of time, the technology has also been continuously improved.

In the past, when I first got involved in this synthesis, the classic method was often used as the basis. First, adipic acid was taken as the starting material, and it was converted into adipic acid chloride by acylation. This process of acylation needs to be carefully controlled to avoid overheating and causing side reactions to clump. Then, ammonia gas was introduced to combine adipic acid chloride with ammonia, and then adipic acid monoamide was obtained. In this step, the rate of ammonia gas penetration and the pH of the reaction system are all key, and if there is a slight difference, the product will be impure.

Then, the method of Hofmann degradation of adipic acid monoamide is carried out. This degradation technique requires the assistance of strong bases, and the reaction conditions are harsh. Bromine and strong bases are used to co-operate to convert the amide group into an amino group, and 6-aminocaproic acid is obtained. However, this product is often mixed with impurities and needs to be purified by recrystallization to obtain pure 6-aminocaproic acid.

When 6-aminocaproic acid is obtained, it can be advanced to the step of trifluoroacetylation. Using 2,2,2-trifluoroacetyl chloride as an acylating agent, in a suitable solvent, such as dichloromethane, etc., it is combined with 6-aminocaproic acid. This step requires the presence of an acid binding agent to remove the acid generated by the reaction and ensure a smooth reaction. After the reaction, after extraction, drying, column chromatography and other means, the final product is (2S) -2-amino-6- [ (2,2,2-trifluoroacetyl) amino] hexanoic acid.

Today, the method of synthesis has also changed. The method of biological enzyme catalysis has emerged. Finding a suitable enzyme and directing the substrate under mild conditions can not only reduce the reaction steps, but also have high selectivity and good product purity. There is also a method of microwave-assisted synthesis, which uses microwave energy to accelerate the reaction and improve the production effect when the reaction is reduced. However, although these methods have their own advantages, they need to be carefully selected according to many factors such as actual needs, cost calculation, and product requirements.

What is the price range of (2S) -2-amino-6- [ (2,2,2-trifluoroacetyl) amino] hexanoic acid in the market?

Wuweiwen (2S) -2 -amino-6- [ (2,2,2 -trifluoroacetyl) amino] hexanoic acid is the exact price range on the market. This compound may be a fine chemical involved in the fields of biochemistry and medicine. Its price is often affected by many factors.

First, the difficulty of preparation is the key factor. If the synthesis process is complicated, multiple steps of reaction, harsh reaction conditions, or special reagents and catalysts are required, the production cost will rise, and the price will also be high.

Second, purity has a great impact. High purity products are in high demand for scientific research and high-end pharmaceutical applications, but preparation is more difficult, so the price must be higher than that of low purity products.

Third, the market supply and demand relationship also affects its price. If the demand is strong and the supply is limited, the merchant may raise the price due to the situation; if the supply is sufficient and the demand is weak, the price will decline.

Fourth, the source is different from the brand. Well-known manufacturers, due to excellent craftsmanship and strict quality control, the product price may be high; while emerging manufacturers compete for the market, the price may be slightly lower.

To know the exact price range, you can consult in detail on the chemical product trading platform, reagent supplier, or communicate with industry insiders and relevant manufacturers to obtain the actual price range.