What is the chemical structure of (2RS, 3SR) -3- (2-chlorophenyl) -2- (4-fluorophenyl) - [ (+ 1H-1,2,4-triazol-1-yl) methyl] oxirane

This is the chemical structure analysis of (2RS, 3SR) -3- (2-chlorophenyl) -2- (4-fluorophenyl )-[( + 1H-1,2,4-triazole-1-yl) methyl] ethylene oxide.

Among its structures, ethylene oxide is the core mother ring, with 4-fluorophenyl at the 2nd position and 2-chlorophenyl at the 3rd position. And an epoxy structure is formed between the 2,3-carbon atoms of ethylene oxide, which gives the compound unique reactivity. Furthermore, the carbon atom at the second position of ethylene oxide is also connected with [ (+ 1H-1,2,4-triazole-1-yl) methyl] groups. The 1,2,4-triazole ring is connected to the methyl group through the 1-position nitrogen atom, and then the methyl group is connected to the 2-position carbon atom of ethylene oxide.

In this compound, the electronic and spatial effects of the substituents such as chlorine atom, fluorine atom, and triazole ring interact with the ethylene oxide ring, which has a great impact on the physicochemical properties and biological activities of the compound. The complexity of its structure determines that it may have various chemical reaction properties and potential biological activities, and may have important research value in the field of organic synthesis and drug development.

What are the physical properties of (2RS, 3SR) -3- (2-chlorophenyl) -2- (4-fluorophenyl) - [ (+ 1H-1,2,4-triazol-1-yl) methyl] oxirane

(2RS, 3SR) -3- (2-chlorophenyl) -2- (4-fluorophenyl )-[( + 1H - 1,2,4-triazole-1-yl) methyl] ethylene oxide This substance has unique physical properties. Looking at its state, at room temperature, it is mostly solid, uniform and fine, like the jade of heaven, standing in the case, it has its own calm state.

Depending on its color, it is often white or off-white, pure and free of variegation, such as the first snow in winter, without dyeing dust, highlighting its pure essence.

As for its melting point, it has been determined by many parties and is about a specific temperature range. This temperature is like a cardinal of physical state changes, and when it reaches it, the solid state gradually melts and turns into a smart liquid flow. In common organic solvents, its solubility also follows a regular pattern. In some organic solvents, it can be slowly dissolved, such as salt melting in water, and gradually fusing with the solvent; in other solvents, it is difficult to be compatible, just like oil and water, which are distinct.

Its density is also a key physical property. Compared with water, it is lighter or heavier. This characteristic has an impact in many application scenarios, and is related to the fluctuation and mixing of substances.

In addition, its volatility is very small, it stands in the air, like a restrained person, does not easily emit itself, and can maintain its inherent shape and properties for a long time. These physical properties are related to each other, and together outline the unique physical appearance of (2RS, 3SR) -3- (2-chlorophenyl) -2- (4-fluorophenyl )-[( + 1H-1,2,4-triazole-1-yl) methyl] ethylene oxide, which lays the fundamental foundation for its application in various fields.

What is the application field of (2RS, 3SR) -3- (2-chlorophenyl) -2- (4-fluorophenyl) - [ (+ 1H-1,2,4-triazol-1-yl) methyl] oxirane

(2RS, 3SR) - 3 - (2 - chlorophenyl) - 2 - (4 - fluorophenyl ） - [（ + 1H - 1,2,4 - triazole - 1 - yl) methyl] ethylene oxide has a wide range of uses. This compound is used in the field of medicine, or has antifungal effects. The ancient people in the art of creation, pay attention to making the best use of things, and use it to explore the characteristics of various substances. This compound may also be analogous. In medicine, it has been studied by experts, or it can be used for diseases caused by specific fungi, such as skin tinea, deep fungal infections, etc., to inhibit or kill fungi.

In the field of pesticides, there is also potential. In ancient agriculture, attention was paid to pest prevention and income protection. Today, this compound may be used to create new pesticides. It may have a good inhibitory effect on pathogenic fungi of some crops, so as to protect crops, protect grain vegetables and fruits from fungi, and ensure harvests. Just like the ancients carefully tended farmland and used various methods to resist pests and diseases.

In addition, in the field of materials science, there is also potential. The preparation and application of materials in "Tiangong Kaiwu" are all exquisite. The unique structure of this compound may enable it to play a role in the modification of polymer materials, such as enhancing the stability of materials, improving the antibacterial properties of materials, etc., contributing to the development of materials science, just as the ancients continuously explored and innovated in the application of materials, exploring new uses.

What is the synthesis method of (2RS, 3SR) -3- (2-chlorophenyl) -2- (4-fluorophenyl) - [ (+ 1H-1,2,4-triazol-1-yl) methyl] oxirane

The synthesis method of (2RS, 3SR) -3- (2-chlorophenyl) -2- (4-fluorophenyl )-[( + 1H-1,2,4-triazole-1-yl) methyl] ethylene oxide is an important matter for chemical synthesis. To prepare this substance, you can start from the following steps.

The first step is to find a suitable starting material. Choose 2-chlorobenzaldehyde and 4-fluoroacetophenone as the starting base, and the two interact in an alkaline environment by the method of hydroxyaldehyde condensation. Alkali, such as sodium hydroxide or potassium hydroxide aqueous solution, can provide a suitable environment for the reaction. This step of the reaction can connect the two to obtain the product in the enol-containing structure. < Br >
In the second step, the middle product is epoxidized. Choose a suitable epoxidizing reagent, such as m-chloroperoxybenzoic acid (m-CPBA), and carefully add it to the reaction system. This reagent has high activity and can epoxidize the double bond of enol, and then obtain the epoxy structure of the target. During the reaction, pay attention to the control of temperature and reaction time to ensure that the reaction is moderate and the product is pure.

Furthermore, under appropriate conditions, introduce 1H-1,2,4-triazole-1-ylmethyl. Choose 1H-1,2,4-triazole and the intermediate product containing halogenated methyl, and react under alkali catalysis. The base can be potassium carbonate, etc., and the halogenated methyl has good activity. It can combine with the nitrogen atom of triazole to finally obtain (2RS, 3SR) -3- (2-chlorophenyl) 2- (4-fluorophenyl )-[( + 1H-1,2,4-triazole-1-yl) methyl] ethylene oxide.

After each step of reaction, it needs to be separated and purified by methods such as column chromatography, recrystallization, etc., to remove impurities and improve the purity of the product before obtaining a pure target product.

What is the market outlook for (2RS, 3SR) -3- (2-chlorophenyl) -2- (4-fluorophenyl) - [ (+ 1H-1,2,4-triazol-1-yl) methyl] oxirane?

(2RS, 3SR) - 3 - (2 - chlorophenyl) - 2 - (4 - fluorophenyl ） - [（ + 1H - 1,2,4 - triazole - 1 - yl) methyl] ethylene oxide, which is an organic compound. The discussion of its market prospect is like looking at the business situation of the past, and it needs to be reviewed from many parties.

Looking at its application in the field of medicine, in recent years, the research of medicine has become popular, and there is a great demand for compounds with unique structures and activities. The unique structure of this compound may make it stand out in the research and development of antifungal and antiviral drugs. Due to the infestation of fungi and viruses, it has always been a problem for physicians. If this compound can be skillfully researched and used to help overcome these problems, its market will be wide. And the current pharmaceutical market is huge and expanding, and the demand for new ingredient drugs is increasing unabated. If this compound can be successfully applied in this field, it will be rewarded handsomely.

In the field of pesticides, current farming seeks efficient and green pesticides. If this compound has insecticidal and bactericidal activities, and is environmentally friendly, it is in line with the current trend of pesticide development. Nowadays, the concept of environmental protection is deeply rooted in the hearts of the people, and traditional pesticides are gradually being eliminated due to the disadvantages of pollution. If this compound can take into account ecology while ensuring the efficacy of the drug, it will be able to win a place in the pesticide market and meet the dual needs of farmers and ecology.

However, its market prospects are not without worries. The research and development of organic compounds often needs to go through a complicated process, from experimental research to large-scale production, with many obstacles. The optimization of the synthesis process and the improvement of the yield are all difficult problems. And the market competition is fierce, and similar or alternative compounds are also competing. If you can't take the lead in research and development progress, cost control, and performance optimization, it may be difficult to stand in the tide of the market.

In summary, (2RS, 3SR) -3- (2-chlorophenyl) -2- (4-fluorophenyl ） - [（ + 1H-1,2,4-triazole-1-yl) methyl] ethylene oxide market prospects are considerable, but also need to overcome many difficulties in order to bloom in the market.