What is the chemical structure of (2R) -2- (4- {[5- (trifluoromethyl) pyridin-2-yl] oxy} phenoxy) propanoic acid

(2R) -2- (4- {[5- (trifluoromethyl) pyridine-2-yl] oxy} phenoxy) propionic acid, the chemical structure of this compound can be analyzed as follows.

Looking at its name, first on the main structure, it is propionic acid, that is, a carboxyl group (-COOH) containing a basic skeleton with three carbon atoms, and the second carbon atom is marked with (2R), which means that its three-dimensional configuration is R-type.

Looking at the substituent part again, there is a complex substituent on the 2-position carbon of propionic acid. This substituent starts from a phenoxy group, that is, the benzene ring is connected to the oxygen atom; at the 4-position of the benzene ring, there is another part connected, which is {[5- (trifluoromethyl) pyridine-2-yl] oxy}. In this part, the 2-position of the pyridine ring is connected to the oxygen atom, and the 5-position of the pyridine ring has trifluoromethyl (-CF 🥰).

In summary, the chemical structure of this compound is based on propionic acid as the main body, and there are substituents containing phenoxy and trifluoromethylpyridinoxy at specific positions, showing a unique chemical structure.

What are the main uses of (2R) 2- (4- {[5- (trifluoromethyl) pyridin-2-yl] oxy} phenoxy) propanoic acid

(2R) -2- (4- {[5- (trifluoromethyl) pyridine-2-yl] oxy} phenoxy) propionic acid, this is an organic compound that has important uses in many fields.

In agriculture, it is often used as a herbicide component. With its unique chemical structure, it can precisely inhibit the growth of specific weeds, and has a significant effect on broadleaf weeds. Weeds grow in farmland and compete with crops for nutrients, water and sunlight, which seriously affects crop yield and quality. This compound can interfere with the physiological processes of weeds, such as inhibiting the activity of enzymes related to photosynthesis of weeds, causing weeds to fail to synthesize energy normally, and then wither and die, ensuring a good growth environment for crops and improving crop yield and quality.

In the field of pharmaceutical research and development, it also has certain potential value. Due to its structural properties, it may interact with specific biological targets. Scientists can develop drugs with specific pharmacological activities by modifying and modifying its structure, which can be used to treat certain diseases. For example, study its binding mode with protein receptors, develop targeted therapeutic drugs, and provide ideas and bases for the creation of new drugs.

In the field of organic synthesis, it is an important intermediate. Organic synthesis aims to build complex organic molecules. The structure of the compound contains multiple reactive functional groups, such as carboxyl groups, phenoxy groups, etc. Chemists can use these functional groups to carry out various chemical reactions, such as esterification reactions, substitution reactions, etc., to synthesize more complex and functionally unique organic compounds, expand the chemical boundaries of organic synthesis, and provide a material foundation for the development of materials science, medicinal chemistry, and other fields.

What are the synthesis methods of (2R) -2- (4- {[5- (trifluoromethyl) pyridin-2-yl] oxy} phenoxy) propanoic acid

The synthesis method of (2R) -2- (4- {[5- (trifluoromethyl) pyridine-2-yl] oxy} phenoxy) propionic acid, let me describe in detail.

First, the starting material can be used for this purpose through a multi-step reaction. First, take the appropriate phenolic compound and make it with a halide containing 5- (trifluoromethyl) pyridine-2-yl, under the catalysis of a base, carry out nucleophilic substitution reaction. A base, such as potassium carbonate, is heated and stirred in a suitable organic solvent, such as N, N-dimethylformamide (DMF), to cause the oxygen atom of the phenol to attack the carbon atom of the halide and form an ether bond to obtain a phenoxy intermediate containing 5- (trifluoromethyl) pyridine-2-yloxy.

Second, the resulting intermediate is reacted with a suitable halopropionate in the presence of a base. The alkali is selected from sodium hydride, etc., in an anhydrous environment, such as anhydrous tetrahydrofuran, the α-carbon atom of the halogenated propionate is subjected to alkali action to generate carbon negative ions, which then attack the appropriate position on the benzene ring of the above intermediate to form a new carbon-carbon bond.

Furthermore, the resulting ester product is hydrolyzed, treated with a dilute acid or alkali solution, such as an aqueous sodium hydroxide solution, heated and refluxed, and the ester bond is broken to obtain the corresponding carboxylate. After acidification, it is adjusted to an appropriate pH value with hydrochloric acid, that is, (2R) -2- (4- {[5- (trifluoromethyl) pyridine-2-yl] oxy} phenoxy) propionic acid is precipitated. < Br >
Or, another way can be obtained. First synthesize a borate containing 5- (trifluoromethyl) pyridine-2-yl, and a halogenated phenoxy compound. Under the participation of palladium catalysts, such as tetra (triphenylphosphine) palladium (0) and bases, Suzuki (Suzuki) coupling reaction is carried out to obtain a phenoxy product containing 5- (trifluoromethyl) pyridine-2-yloxy. The subsequent steps are similar to the above. After reaction with halopropionate, hydrolysis and acidification, the target product can also be obtained.

The key to the synthesis lies in the control of the reaction conditions at each step, such as temperature, reaction time, reagent ratio, etc., which are all related to the yield and purity of the product.

What are the physical properties of (2R) 2- (4- {[5- (trifluoromethyl) pyridin-2-yl] oxy} phenoxy) propanoic acid

(2R) -2- (4- {[5- (trifluoromethyl) pyridine-2-yl] oxy} phenoxy) propionic acid, this is an organic compound. Its physical properties are quite critical, and it is related to the performance and application of this substance in many scenarios.

Looking at its properties, it is mostly white to white-like solid under normal conditions. The texture is fine and uniform, and it shows a sense of purity visually. This morphology is conducive to storage and transportation. Because it is relatively stable, it is not easy to change significantly under conventional conditions.

In terms of melting point, it is about [specific melting point value], and this melting point is one of the important characteristics of this compound. The precise value of the melting point defines the critical temperature for its transition from solid to liquid. In practical operations such as purification and processing, the melting point data can provide a key basis for temperature control, ensuring that the operation is carried out in a suitable temperature range and avoiding changes in the properties of substances due to improper temperature.

Solubility is also not to be underestimated. It exhibits a certain solubility in organic solvents such as ethanol and acetone. In ethanol, a uniform solution can be formed under specific temperature and concentration conditions. This property allows the compound to be fully dispersed in the reaction system using ethanol as a solvent, effectively participating in the reaction and improving the reaction efficiency. In water, its solubility is relatively limited, but a small amount of dissolved part may have a subtle effect on some properties of the aqueous phase system, which needs to be considered in chemical processes or environmental applications involving the aqueous phase.

In addition, the density of the compound also has a specific value, [specific density value], which determines its sedimentation and distribution in different media, and is of great significance for mixing and separation processes in chemical production.

The above physical properties, such as properties, melting point, solubility, density, etc., are related to each other and affect each other, jointly constructing the unique physical properties of (2R) -2- (4- {[5- (trifluoromethyl) pyridine-2-yl] oxy} phenoxy) propionic acid, laying the foundation for its research and application in many fields such as chemical industry and medicine.

What is the market prospect of (2R) 2- (4- {[5- (trifluoromethyl) pyridin-2-yl] oxy} phenoxy) propanoic acid

(2R) -2- (4- {[5- (trifluoromethyl) pyridin-2-yl] oxy} phenoxy) propionic acid, this compound has great potential in the field of agrochemical and bright prospects.

It is considered to be in the field of herbicides, and has excellent efficacy in the control of broadleaf weeds. With the increasing demand for modern agriculture in weed control, there is an urgent need for efficient, safe and environmentally friendly herbicides. ( 2R) -2- (4- {[5- (trifluoromethyl) pyridine-2-yl] oxy} phenoxy) propionic acid, with its unique chemical structure, can precisely act on specific physiological links of weeds, achieve high-efficiency herbicidal effect, and have slight harm to crops. It is in line with the demands of modern agriculture. In the field of farmland weed prevention and control, the market expansion space is broad.

In the field of cash crops, such as orchards, tea gardens, etc., the growth of broadleaf weeds often causes damage to the yield and quality of cash crops. This compound can effectively deal with such weeds, ensure the growth of cash crops, and improve economic benefits. With the expansion of cash crop planting scale and the advancement of fine management, its application in this field is expected to continue to grow.

However, market competition cannot be ignored. Many agrochemical companies are competing to develop new herbicides, (2R) -2- (4- {[5- (trifluoromethyl) pyridin-2-yl] oxy} phenoxy) propionic acid To stabilize the market, it is necessary to continuously optimize the production process, reduce costs, and enhance product competitiveness. At the same time, strengthen marketing activities and application technical services to help farmers use it scientifically, in order to emerge in the market competition and enjoy the dividends of market growth.