What is the chemical structure of (2R) -1- (2,4-difluorophenyl) -2- (((tetrahydro-2H-pyran-2-yl) oxy) propyl-1-one

The chemical structure of (2R) -1- (2,4-difluorophenyl) -2- ((tetrahydro-2H-pyran-2-yl) oxy) propyl-1-ol is a key characterization of specific compounds in the field of organic chemistry.

The structure of this compound can be analyzed as follows. First, (2R) represents a specific stereoconfiguration of the compound at carbon atom 2, and the "R" configuration indicates the spatial arrangement of its chiral centers, which is determined based on the Cahn-Ingold-Prelog rule.

Next, 1- (2,4-difluorophenyl) means that a 2,4-difluorophenyl group is connected to the main chain carbon atom No. 1. In this phenyl group, the benzene ring is replaced by the fluorine atom at the positions of the No. 2 and No. 4 carbon atoms, respectively. The unique electronegativity of the fluorine atom has a profound impact on the electron cloud distribution and chemical properties of the whole compound.

Look again, 2 - ((tetrahydro-2H-pyran-2-yl) oxygen), that is, the No. 2 carbon atom is connected to an oxygen-containing heterocyclic structure. This heterocyclic ring is tetrahydro-2H-pyran-2-yl, which is connected to the main chain through the oxygen atom. The tetrahydro-2H-pyran ring is a saturated oxygen-containing six-membered heterocyclic ring, and the existence of this ring endows the compound with specific steric resistance and electronic effects.

Finally, propyl-1-ol shows that the main chain is a propanol structure containing three carbon atoms, and the hydroxyl group is located on the No. 1 carbon atom. This hydroxyl group makes the compound have certain hydrophilicity and reactivity, and can participate in many chemical reactions, such as esterification and oxidation.

In summary, the chemical structure of (2R) -1- (2,4-difluorophenyl) -2- ((tetrahydro-2H-pyran-2-yl) oxy) propyl-1-alcohol is composed of the chiral center, fluorophenyl group, oxygen-containing heterocyclic ring and alcohol hydroxyl group of a specific stereoconfiguration. The interaction of each part determines the unique physical and chemical properties of the compound.

What are the physical properties of (2R) -1- (2,4-difluorophenyl) -2- (((tetrahydro-2H-pyran-2-yl) oxy) propyl-1-one

(2R) -1- (2,4-diallyl) -2- ((tetrahydro-2H-pyran-2-yl) oxy) propyl-1-ol, the physical properties of this substance are as follows:

It is mostly liquid at room temperature and pressure. Its molecular structure contains specific carbon chains and functional groups, which endows it with unique solubility. The substance exhibits good solubility in organic solvents, such as common organic solvents such as ethanol and ether. This is due to the formation of suitable interactions between polar groups in its molecules and organic solvent molecules, such as van der Waals force, hydrogen bonds, etc., so that the molecules can be uniformly dispersed in the solvent.

Compared with water, the density of (2R) -1- (2,4-diallyl) -2- ((tetrahydro-2H-pyran-2-yl) oxy) propyl-1-ol is relatively small. This is determined by the composition and structure of its molecules. The hydrocarbon chain and the specific heterocyclic structure make the mass per unit volume relatively light.

Regarding the boiling point, the boiling point of this substance is moderate. The interaction forces between molecules, including van der Waals forces and weak hydrogen bonds, determine that it needs to absorb a certain amount of energy to overcome the attractive forces between molecules and achieve the transition from liquid to gas.

In addition, the refractive index of the substance also has certain characteristics. The refractive index is related to the electron cloud distribution and structural regularity of the molecule. By measuring its refractive index, it can assist in the identification of the substance. Under the light of a specific wavelength, its refractive index shows a specific value, providing a basis for the identification and purity detection of the substance.

Its appearance may appear colorless to light yellow transparent, which is due to the absorption and scattering characteristics of the molecular structure of light, and does not produce strong absorption of specific bands of visible light, so it presents a relatively light color.

What are the synthesis methods of (2R) -1- (2,4-difluorophenyl) -2- (((tetrahydro-2H-pyran-2-yl) oxy) propyl-1-one

The synthesis of (2R) -1- (2,4-dichlorophenyl) -2- ((tetrahydro-2H-pyran-2-yl) oxy) propyl-1-ol is a key task in the field of organic synthesis. This compound has a unique structure and has potential uses in medicine, pesticides and other fields, and the synthesis method is very important.

In the past, to obtain this compound, or follow the traditional way of organic synthesis. The first method is to take a suitable halogenated aromatic hydrocarbon, such as 2,4-dichlorohalobenzene, make it with a compound with active hydrogen, catalyze it with a strong base, perform a nucleophilic substitution reaction, and introduce a side chain containing active groups. This side chain may be a functional group with further reactivity, such as a halogen atom or a hydroxyl group derivative. Subsequently, the reactive hydroxyl and other functional groups in it are protected by a protective group strategy, such as tetrahydropyranyl. The protection process uses alcohol and dihydropyrane under acid catalysis to form a tetrahydropyrane ether structure, which is stable and can protect hydroxyl groups in subsequent reactions.

Next, another key site is constructed. Under the action of metal catalysts or bases, nucleophilic substitution or similar reactions are carried out with halogenated alkanes or similar electrophilic reagents with specific structures and intermediates of protected hydroxyl groups to build a carbon skeleton of the target compound. After the reaction is completed, the protective group is removed, and the target product (2R) -1- (2,4-dichlorophenyl) -2- ((tetrahydro-2H-pyran-2-yl) oxy) propyl-1-ol can be obtained. However, this traditional method, the steps may be proliferative, the conditions may be harsh, and the yield may be unsatisfactory.

In recent years, new synthesis strategies have emerged. First, enzyme-catalyzed synthesis method. Utilize specific enzymes, such as lipase or other selective enzymes, to catalyze the reaction under mild conditions. Enzymes are highly selective and can precisely catalyze specific site reactions in complex molecular structures, reducing side reactions and improving yield and purity. Second, the tandem reaction of transition metal catalysis. With the unique catalytic performance of transition metal catalysts, multi-step reactions can occur continuously in the same system without separating intermediates, simplifying steps and improving atomic economy. These new methods open up new avenues for the synthesis of (2R) -1- (2,4-dichlorophenyl) -2- ((tetrahydro-2H-pyran-2-yl) oxy) propyl-1-ol, or become the mainstream direction of future synthesis.

What are the application fields of (2R) -1- (2,4-difluorophenyl) -2- (((tetrahydro-2H-pyran-2-yl) oxy) propyl-1-one

(2R) -1- (2,4-dichlorophenyl) -2- ((tetrahydro-2H-pyran-2-yl) oxy) propyl-1-ol, this compound is widely used in the field of medicinal chemistry. It is often used as a key intermediate in drug synthesis, through which it can build complex drug molecular structures, providing the possibility for innovative drug development.

In the creation of antifungal drugs, this compound can be chemically reacted with other active groups to build molecules with high targeted inhibitory activity against fungi, helping to solve the problem of fungal infection. In the field of organic synthesis chemistry, it participates in the construction process of many complex organic molecules with its unique structure and reactivity. Chemists use their characteristics to ingeniously design reaction routes to achieve the synthesis of organic compounds with special functions or structures.

This compound also plays an important role in the study of the structure-activity relationship of medicinal chemistry. By modifying and modifying its structure, observing biological activity changes can reveal the intrinsic relationship between structure and activity, and lay a theoretical foundation for the design of more efficient and low-toxicity new drugs. In the long journey of new drug development, (2R) -1- (2,4-dichlorophenyl) -2- ((tetrahydro-2H-pyran-2-yl) oxy) propyl-1-ol is like a key, providing the possibility to open the door to new drug treatment options, and playing a potential and key role in the fight against diseases.

What is the market outlook for (2R) -1- (2,4-difluorophenyl) -2- (((tetrahydro-2H-pyran-2-yl) oxy) propyl-1-one?

Now there are (2R) -1- (2,4-dichlorophenyl) -2- ((tetrahydro-2H-pyran-2-yl) oxy) propyl-1-ol, and its market prospects are as follows:

This compound may have unique application potential in the field of pharmaceutical chemistry. In the process of drug development, the specific group combination in its structure may make it compatible with certain disease targets. For example, the presence of 2,4-dichlorophenyl and (tetrahydro-2H-pyran-2-yl) oxy may endow the compound with unique pharmacological activity.

In the field of antimicrobial drug research and development, chlorophenyl-containing often has antibacterial effect, while tetrahydropyranoxy may improve the fat solubility and metabolic stability of drugs. In this way, (2R) -1- (2,4-dichlorophenyl) -2- ((tetrahydro-2H-pyran-2-yl) oxy) propyl-1-ol may be a lead compound of new antibacterial drugs. After structural modification and optimization, it is expected to produce new antibacterial drugs with excellent efficacy and small side effects.

In the agricultural field, such compounds containing specific groups or have agricultural activities, such as as as fungicides, may be helpful for crop disease control. Due to its special structure, it may interfere with the physiological process of pathogenic bacteria, achieving the purpose of disease prevention and control, crop yield and quality.

However, its market prospect also faces challenges. The drug research and development process is long and expensive, and from lead compounds to marketed drugs, it needs to go through a lot of experiments and approval links. And the market competition is fierce, and similar or similar compounds may already exist in the market.

But overall, (2R) -1- (2,4-dichlorophenyl) -2- ((tetrahydro-2H-pyran-2-yl) oxy) propyl-1-ol can effectively solve the research and development problems, and with its unique structure and potential activity, it may be able to open up a market in the fields of medicine and agriculture.