Name | 2-bromo-6-fluorophenol |
Molecular Formula | C6H4BrFO |
Molecular Weight | 191.00 |
Appearance | Solid |
Melting Point | 39 - 43 °C |
Boiling Point | 202 - 203 °C |
Density | 1.752 g/cm³ |
Solubility In Water | Slightly soluble |
Flash Point | 86 °C |
Refractive Index | 1.574 |
Pka | 8.39 |
Chemical Formula | C6H4BrFO |
Molar Mass | 191.00 g/mol |
Appearance | Solid (predicted) |
Boiling Point | Approx. 215 - 220 °C (predicted) |
Melting Point | Approx. 45 - 49 °C (predicted) |
Density | Approx. 1.74 g/cm³ (predicted) |
Solubility In Water | Slightly soluble |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
Flash Point | Approx. 84 °C (predicted) |
Pka Value | Approx. 8 - 9 (predicted) |
Odor | Phenolic odor (predicted) |
Chemical Formula | C6H4BrFO |
Appearance | Solid (Typical) |
Boiling Point | Approximately 205 - 210 °C |
Melting Point | Around 35 - 40 °C |
Density | ~1.76 g/cm³ |
Solubility In Water | Low |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
Flash Point | ~90 °C |
Pka | Estimated around 8 - 9 |
Odor | Characteristic phenolic odor |
Chemical Formula | C6H4BrFO |
Appearance | Solid (Typical) |
Color | White to Off - white |
Odor | Characteristic |
Melting Point | 48 - 52 °C |
Boiling Point | 222 - 224 °C |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
Density | 1.768 g/cm³ (estimated) |
Flash Point | 98.1 °C |
What are the physical properties of 2-bromo-6-fluorophenol?
2-% mercury-6-deuterium Polonium bismuth, its physical properties are as follows:
Mercury, at room temperature, is a liquid metal with a white and shiny color and good fluidity. Its density is quite high, about 13.59 grams/cubic centimeter, so it can roll on the surface of other substances. The melting point of mercury is extremely low, -38.87 ° C, and the boiling point is 356.6 ° C. Mercury is volatile and can slowly evaporate into mercury vapor at room temperature. This vapor is highly toxic. If inhaled, it will damage the nervous system, kidneys and other organs. Mercury is relatively stable in chemical properties and is not easy to combine with oxygen under normal conditions. However, when heated, it can react with oxygen to form mercury oxide. And mercury can dissolve many metals to form amalgam, which is widely used in metallurgy and other fields.
Deuterium Polonium Bismuth, Polonium is a radioactive metal element, bismuth is a metal element, and deuterium is an isotope of hydrogen. Polonium is highly radioactive, and it releases alpha particles when it decays, which is extremely harmful to organisms. Bismuth is brittle, with a low melting point of 271.3 ° C and a boiling point of 1560 ° C. Bismuth has poor electrical and thermal conductivity, is relatively stable in air, and will form an oxide film on the surface and change color. Deuterium is a stable isotope of hydrogen, and its nucleus has more neutrons than hydrogen. Its properties are similar to hydrogen, but its mass is slightly larger. Deuterium is commonly found in heavy water, and in the field of nuclear physics, such as nuclear fusion research, deuterium is an important raw material. And the physical and chemical properties of compounds containing deuterium are slightly different from those containing hydrogen. This difference is very important in chemical research and the preparation of some special materials.
What are the chemical properties of 2-bromo-6-fluorophenol?
2-% nitrile-6-alkoxyquinoline is a class of organic compounds with unique chemical properties and wide use in many fields.
The nitrile group (-CN) is an important functional group of this compound and has high reactivity. The nitrile group can be converted into a carboxyl group (-COOH) by hydrolysis, which can occur under acidic or basic conditions. Taking acid-catalyzed hydrolysis as an example, the nitrile group is first added to water to form imine acid, which is unstable, and then rearranged to form carboxylic acid. For example, under the catalysis of sulfuric acid, the nitrile group in 2-nitrile-6-alkoxyquinoline can be gradually converted into carboxyl group, which provides an effective way for the synthesis of carboxyquinoline derivatives.
Nitrile groups can also participate in the reduction reaction. Under the action of strong reducing agents such as lithium aluminum hydride (LiAlH), nitrile groups can be reduced to amine groups (-NH ²). In this way, after the reduction of 2-nitrile-6-alkoxy quinoline, an amine group can be introduced into the quinoline ring, which lays the foundation for the preparation of amine-containing functionalized quinoline compounds, which may have potential biological activities in the field of medicinal chemistry. The alkoxy group at the
6-position (-OR, R is alkyl) also affects the chemical properties of the compound. The alkoxy group is the power supply subgroup, which affects the electron cloud density distribution of the quinoline ring through electronic effects. This increases the electron cloud density at specific locations on the quinoline ring, making it more susceptible to electrophilic substitution reactions. For example, in halogenation reactions, the electron cloud density of quinoline ring ortho and para-sites is relatively high due to the action of alkoxy groups, and halogen atoms are more inclined to replace hydrogen atoms at these locations, thus synthesizing specific halogenated 2-nitrile-6-alkoxy quinoline derivatives, providing key intermediates for subsequent derivatization reactions.
In addition, 2-nitrile-6-alkoxy quinoline has a certain polarity due to the presence of nitrile and alkoxy groups in the molecule, and has specific solubility in organic solvents. Appropriate selection of solvent can achieve the separation and purification of the compound, and its solubility characteristics also affect its reaction behavior in solution, such as affecting the reaction rate and selectivity.
What fields are 2-bromo-6-fluorophenol used in?
2-% E6% BA% B4 - 6-%E6%B0%9F%E8%8B%AF%E9%85%9A%E5%9C%A8%E4%B8%9C%E6%B0%B4%E6%B4%8B%E4%B8%9C%E6%B5%B7%E5%8C%BA%E5%9F%9F%E3%80%81%E5%8D%97%E6%B5%B7%E5%8C%BA%E5%9F%9F%E4%BB%A5%E5%8F%8A%E4%B8%9C%E5%8D%97%E4%BA%9A%E5%92%8C%E5%8D%97%E4%BA%9A%E4%B8%80%E4%BA%9B%E5%B8%82%E5%9F%8E%E5%9C%B0%E5%8C%BA%E7%AD%89%E5%9C%B0%E5%8C%BA%E6%9C%89%E5%BA%94%E7%94%A8%E3%80%82
It is quite useful in the coast of the East China Sea and the South China Sea. In coastal areas, it can protect the embankment. Coastal areas are often invaded by sea tides, the wind is turbulent, and the embankment is easy to destroy. 2-% E6% BA% B4 - 6-%E6%B0%9F%E8%8B%AF%E9%85%9A placed here, it can slow down the power of the tide, make the embankment strong, and protect the coastal people's fields.
It is also very useful in the islands of the South China Sea and nearby waters. It can help the exploration and development of marine resources. The South China Sea is vast and rich in resources. 2-% E6% BA% B4 - 6-%E6%B0%9F%E8%8B%AF%E9%85%9A can be used for deep-sea exploration, exploration of oil and gas, mineral and other resources. And it is also helpful for marine research, which can monitor the marine environment, observe changes in ocean currents, and rise and fall of water temperature, providing a lot of data for marine ecological research.
In some urban areas of South East Asia and South Asia, it can be used for urban construction. Its material is sturdy and durable, and can be used as a building cornerstone to make the building stable. And because of its special structure, it is also effective in flood control and drainage. In case of rainstorms and floods, it can divert water flow, reduce the risk of urban flooding, and ensure the safety of people's lives.
What are the synthesis methods of 2-bromo-6-fluorophenol?
To prepare dihydroxy-6-alkoxy acetophenone, there are many methods, each with its own advantages and disadvantages, which are described in detail as follows:
One of them is the Foucault acylation method. Using benzene as the starting material, under the catalysis of anhydrous aluminum trichloride and other Lewis acids, Foucault acylation is carried out with the corresponding acyl halide or acid anhydride, and acetophenone derivatives can be obtained first. This reaction condition needs to be strictly controlled, and the anhydrous environment is very important, otherwise the catalyst activity will be suppressed. The amount of Lewis acid also needs to be precise. More side reactions are frequent, and less reactions are slow. Subsequent steps of hydroxylation and alkoxylation are followed to achieve the synthesis of the target product. Hydroxylation can be used with suitable nucleophiles, and hydroxyl groups can When alkoxylating, select the appropriate halogenated alkanes and bases to promote the smooth integration of alkoxy groups.
The second is the acylation method of phenolic compounds. With specific phenols as the starting material, the phenolic hydroxyl group is first protected to prevent its gratuitous reaction during the acylation process. The selection of protective groups needs to be careful, which is easy to introduce and remove. Commonly used protective groups such as methoxy methyl ethers. After the protection is completed, acylation is carried out with an acylating reagent. This step also requires a suitable catalyst. After the acylation is completed, the protective group is removed, and the alkoxy group is introduced. By carefully designing the reaction sequence and conditions, the target product can be efficiently synthesized.
The third is the Grignard reagent method. The halogenated aromatics are used as raw materials to prepare Grignard reagents, which are then reacted with corresponding carbonyl compounds to form carbon-carbon bonds and form intermediates containing acetophenone structures. In this process, Grignard reagents are prepared under harsh conditions, requiring anhydrous and anaerobic, with extremely high reactivity, and are easily reacted with water vapor and oxygen in the air. Subsequent hydroxylation and alkoxylation are modified to obtain dihydroxyl-6-alkoxy acetophenone.
The above methods have advantages and disadvantages. In actual synthesis, it is necessary to comprehensively weigh factors such as raw material availability, cost considerations, reaction difficulty and product purity, and make careful choices to achieve efficient and economical synthesis.
What is the market outlook for 2-bromo-6-fluorophenol?
Since modern times, the prospects of the city involved by Immortal Toad of Erchuan and Liuchuan have been important to the industry. In the second place, mountains and rivers are shaped, and things are different. However, business matters are affected by many factors.
Today, in the city of Erchuan, the transportation convenience is improving day by day, and there are many businesses in the four directions. This way, the business can be expanded. However, it is also selected like a small area, such as the business of the nearby area, and the local customs and customs. It is also speculated by the merchants. The skills of Immortal Toad of Liuchuan, with their skills, the products produced are of the best quality, and they are respected in the world. However, in order to gain a foothold in a larger city, it still needs to be improved and improved.
As far as the following is concerned, the two cities are like the seedlings of spring, which are flourishing. However, if you want them to flourish and become successful, you need to be well cultivated. With the cooperation of Immortal Six Chuan Toad, it is appropriate to use the two cities to start a business, to expand the road, or to combine the four-sided merchants, to communicate with each other, and to flourish together. And pay attention to the tiredness of business, to treat customers with trust, so that the things that are done can be broadcast by name.
The prospect of the city, there is no shortage of obstacles, but the land benefits of the two cities, plus the skills of Immortal Six Chuan Toad, if you can make good use of it, you will definitely be able to create a world in the business sea, and you can look forward to it.