What is the chemical structure of (1S, 4S) -1,4-bis (4-chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol?

(1S, 4S) -1,4-bis (4-chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol. The chemical structure of this compound is disassembled according to its name. " (1S, 4S) " indicates the configuration of its chiral center, which is a stereochemical identification, indicating that the spatial orientation of carbon atoms at positions 1 and 4 is specific. " 1,4-Bis (4-chloro-2-fluoro-5-nitrophenyl) ", the main chain of the molecule is butane, with one substituent at the 1st and 4th positions. This substituent is (4-chloro-2-fluoro-5-nitrophenyl), which means that on the benzene ring, the 4-position chlorine atom, the 2-position fluoro atom, and the 5-position nitro." Butane-1,4-diol ", the 1-position of the table main chain butane and the 4-position carbon atom are each connected with one hydroxyl group. In summary, its chemical structure is based on butane as the skeleton, with 1 and 4 carbons each connected to a hydroxyl group, and 1 and 4 carbons each connected to a phenyl substituent containing chlorine, fluorine, and nitro groups. The whole is a specific spatial configuration, determined by the chiral central configuration (1S, 4S).

What are the main physical properties of (1S, 4S) -1,4-bis (4-chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol?

(1S, 4S) -1,4-Bis (4-chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol is an important member of the field of organic compounds. Its physical properties contain many key aspects.

The first word melting point, the exact value of the melting point of this substance, is of great significance to its phase transition under specific temperature conditions. Knowing the melting point can accurately control the temperature during synthesis and application to ensure that the reaction and use are in an appropriate phase state.

Solubility is also an important characteristic. In common organic solvents, such as ethanol, dichloromethane, acetone, etc., their solubility characteristics are directly related to whether they can be easily integrated into various reaction systems or used to prepare products in solution state. Good solubility in polar organic solvents means that specific chemical reactions can be carried out by means of polar environments; poor solubility in non-polar solvents can also provide ideas for separation and purification.

In appearance, (1S, 4S) -1,4-bis (4-chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol is mostly solid or crystalline in a specific color and shape. Its color may be white, light yellow, etc., and its shape may be needle-like crystals, bulk crystals, etc. This appearance characteristic is not only conducive to preliminary identification, but also closely related to the way of molecular accumulation and interaction.

Furthermore, density is another important physical parameter of this substance. It is crucial to clarify its density in the operation involving mass and volume conversion, such as formulating a specific concentration solution and determining the volume of the reaction material, etc., to provide basic data for accurate experiments and production.

The above melting point, solubility, appearance, density and other physical properties are of great significance for the research, synthesis and application of (1S, 4S) -1,4-bis (4-chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol, laying the foundation for its application in organic synthesis, materials science and other fields.

What are the synthesis methods of (1S, 4S) -1,4-bis (4-chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol?

The synthesis of (1S, 4S) -1,4-bis (4-chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol is an important research direction in the field of organic synthesis. The synthesis of this compound can follow several different paths.

First, it may be through a nucleophilic substitution reaction as the initial step. Select an appropriate halogenated hydrocarbon and make it react with a phenolic compound containing a specific substituent in an alkaline environment and with the help of a phase transfer catalyst. During this process, the halogen atom of the halogenated hydrocarbon is attacked by the nucleophilic anion of phenoxy, thereby forming a carbon-oxygen bond. Subsequently, the obtained intermediate is subjected to a reduction reaction to reduce the nitro group to an amino group, and then through diazotization and subsequent conversion, the required chlorine and fluorine atoms are introduced to finally achieve the synthesis of the target compound.

Second, benzene ring derivatives can also be considered as the starting material, and appropriate substituents can be introduced into the benzene ring through the Fu-G reaction to construct the key carbon-carbon bond. Subsequently, through a series of oxidation, reduction, halogenation and other reaction steps, the substituents are gradually modified to meet the structural requirements of the target molecule. This path requires fine control of the reaction conditions to ensure the selectivity and yield of each step of the reaction.

In addition, there is a strategy to use butane derivatives as starting materials, first functionalize the two ends of butane, and then couple with chlorine, fluorine and nitro-containing benzene ring derivatives to achieve the construction of the target compound. This coupling reaction may require the help of transition metal catalysts to promote the formation of carbon-carbon bonds.

The various methods for the synthesis of (1S, 4S) -1,4-bis (4-chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol have their own advantages and disadvantages. It is necessary to carefully select the appropriate synthesis path according to the specific experimental conditions, raw material availability and purity requirements of the target product.

What are the applications of (1S, 4S) -1,4-bis (4-chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol?

(1S, 4S) -1,4-Bis (4-chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol is useful in various fields such as medicine and materials.

In the field of medicine, it can be used as a pharmaceutical intermediate. In the method of organic synthesis, after several steps of reaction, it can introduce specific functional groups and convert them into bioactive compounds, which are expected to become new drugs. If it is cleverly modified, it may act on specific biological targets, and it is effective in the treatment of specific diseases, such as tumors and cardiovascular diseases. Because its structure contains chlorine, fluorine, nitro and other groups, it can affect the physical and chemical properties and biological activities of compounds, providing various possibilities for drug development. < Br >
In the field of materials, because the compound contains special functional groups, it can be used to prepare functional materials. It can be introduced into polymer to change the properties of the polymer. Such as enhancing the heat resistance and chemical corrosion resistance of the material, or endowing the material with special properties such as optics and electricity. Or it can be used to prepare liquid crystal materials. With its specific molecular structure, it affects the molecular arrangement and orientation, so that the material exhibits unique liquid crystal properties. It may have applications in display technology.

Furthermore, in the field of chemical research, as a compound with special structure, it can be used to explore the mechanism of chemical reactions. Because of its unique structure, it can exhibit special chemical behavior in the reaction, which helps chemists to deeply understand the reaction process and contributes to the development of organic synthetic chemistry.

What is the market outlook for (1S, 4S) -1,4-bis (4-chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol?

(1S, 4S) -1,4-bis (4-chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol, this compound is still a budding upstart in the industry. In terms of market prospects, it is showing a booming trend, attracting the attention of many people.

Looking at today's market, demand for it in many fields is gradually emerging. In the corner of pharmaceutical research and development, because of its unique chemical structure, it may pave the way for the creation of new specific drugs. Researchers hope to use its characteristics to overcome some difficult diseases, so the exploration and investment in it continue to rise, indicating that it may set off a wave of innovation in the pharmaceutical industry in the future.

In the field of materials science, it can also be seen. Because of some of its special properties, it may be used as a key raw material to create new materials with excellent properties. Materials such as high strength, high temperature resistance and special optical and electrical properties are expected to come out with its help, injecting new vitality into the development of this field.

However, the road ahead for its market is not entirely smooth. The complexity of the synthesis process has resulted in high production costs, which is a thorn hindering its large-scale promotion. And related research is still in a gradual stage, and many properties and application potentials need to be further explored and confirmed. But over time, with the advance of science and technology, process improvement, and cost control, its market prospects may gradually become clear, shining brightly in many fields, and becoming an important force to promote the progress of the industry.