What is the chemical structure of (1R, 4R, 5S) -4- (1,1-Dichloro-2,2,2-trifluoroethyl) -6,6-dimethyl-3-oxabicyclo (3.1.0) hexan-2-one?

This is about the chemical structure of (1R, 4R, 5S) -4- (1,1-dichloro-2,2,2-trifluoroethyl) -6,6-dimethyl-3-oxabicyclo [3.1.0] hexane-2-one. To clarify its structure, it is necessary to analyze it according to the system nomenclature.

" (1R, 4R, 5S) " shows the three-dimensional configuration of this compound. R and S are chiral carbon atom configuration markers, determined according to the Cahn-Ingold-Prelog rule. These three indicate the specific spatial orientation of chiral carbons at positions 1, 4, and 5. < Br >
"4- (1,1-dichloro-2,2,2-trifluoroethyl) ", indicating that there is a substituent at the 4th position of the main ring. This substituent contains monoethyl, and the 1st position of the ethyl group is connected to a dichloro atom and the 2nd position is connected to a trifluoro atom.

"6,6-dimethyl", knowing that the 6th position of the main ring is connected with two methyl groups.

"3-oxabicyclo [3.1.0] hexane-2-one", indicating that the main structure is a dicyclic compound. " 3-Oxygen "shows an oxygen atom in the ring;" 3.1.0 "refers to the fusion of two rings, the larger ring contains 3 non-shared atoms, the smaller ring contains 1 non-shared atom, and the two rings share 2 atoms to form a double ring system containing 6 atoms; the total number of atoms in the" hexane "ring system is 6; the" 2-keto "table 2 has a carbonyl group.

In summary, the chemical structure of (1R, 4R, 5S) -4- (1,1-dichloro-2,2,2-trifluoroethyl) -6,6-dimethyl-3-oxabicyclo [3.1.0] hexane-2-one is a specific three-dimensional configuration, with a specific substituent at a specific position.

What are the physical properties of (1R, 4R, 5S) -4- (1,1-Dichloro-2,2,2-trifluoroethyl) -6,6-dimethyl-3-oxabicyclo (3.1.0) hexan-2-one?

(1R, 4R, 5S) - 4- (1,1-dichloro-2,2,2-trifluoroethyl) - 6,6-dimethyl-3-oxabicyclo (3.1.0) hexane-2-one, this is an organic compound. Its physical properties are quite important, and it is related to many chemical and application fields.

First, the appearance is usually a colorless to light yellow liquid. Under light, it resembles glaze, clear and has a unique luster. This appearance feature is an intuitive feature in many chemical operations and industrial applications.

Besides, the boiling point is about a certain temperature range. Under normal pressure, when it reaches a certain temperature, it will change from liquid to gaseous state. Just like the boiling of water, the molecular energy of this compound is enhanced under the specific heat, breaking free from the liquid phase and rising into the gas phase. This boiling point characteristic is particularly critical in the process of separation and purification. It can be separated from other substances by means of distillation and other means according to the difference in boiling points.

The melting point cannot be ignored either. When the temperature drops to a certain value, the compound solidifies from liquid to solid state, just like the freezing of water in winter. This process is accompanied by energy changes. The exact value of the melting point is an important basis for the determination of the purity and structure of the compound. < Br >
In terms of density, its mass per unit volume at a specific temperature is a certain value. This value determines its position and distribution in a solution or mixed system. If mixed with water, depending on the density difference, it may float on water or sink underwater, which has a significant impact on the design and operation of the reaction system.

Solubility is also a key physical property. The compound dissolves to varying degrees in organic solvents such as ethanol and acetone, just like salts dissolve in water. This property affects the reaction progress, product separation and purification in chemical reactions, drug preparation and other fields, and is an important consideration for experimental design and process optimization.

The physical properties of this compound, such as appearance, boiling point, melting point, density and solubility, are related to each other and affect each other, and are indispensable in chemical research, industrial production and related application fields.

What are the synthesis methods of (1R, 4R, 5S) -4- (1,1-Dichloro-2,2,2-trifluoroethyl) -6,6-dimethyl-3-oxabicyclo (3.1.0) hexan-2-one?

To prepare (1R, 4R, 5S) -4- (1,1-dichloro-2,2,2-trifluoroethyl) -6,6-dimethyl-3-oxabicyclo (3.1.0) hexane-2-one, there are various methods. First, it can be started from a specific enol ether. Take a suitable enol ether, take it under specific conditions, treat it with a suitable reagent, and go through various steps such as addition and cyclization. Second, take a cyclic compound containing the corresponding functional group as a raw material. It can also be prepared by modifying its functional group, such as introducing a halogen atom, adjusting the alkyl structure, and guiding the molecular structure rearrangement and cyclization by means of catalytic reactions. Third, the method of asymmetric synthesis is used. Chiral catalysts or chiral additives are used to intervene in the reaction, and in the process of starting material conversion, the stereochemistry is precisely controlled, so that the reaction tends to produce the desired (1R, 4R, 5S) configuration products. These methods have their own advantages and disadvantages, or the raw materials are easy to obtain but the steps are cumbersome, or the stereoselectivity is good but the cost is high. In actual synthesis, when the availability of raw materials, cost considerations, product purity and configuration requirements, etc., the appropriate method is carefully selected.

What are the applications of (1R, 4R, 5S) -4- (1,1-Dichloro-2,2,2-trifluoroethyl) -6,6-dimethyl-3-oxabicyclo (3.1.0) hexan-2-one?

(1R, 4R, 5S) -4- (1,1-dichloro-2,2,2-trifluoroethyl) -6,6-dimethyl-3-oxabicyclo (3.1.0) hexane-2-one This substance is used in various fields such as agriculture and medicine.

In the field of pesticides, it may have unique insecticidal and insect-suppressing properties. Due to its special chemical structure, it can act on specific physiological targets of pests, disrupt the normal physiological metabolism of pests, such as affecting the signal transduction of the pest's nervous system, or destroying its digestive system function, causing pests to eat, growth and development to be blocked, and then achieve the purpose of preventing and controlling pests, protecting crop growth and maintaining agricultural harvest. < Br >
In the field of medicine, or can be used as an important intermediate in drug synthesis. Based on this, chemically modified and transformed, drugs with novel pharmacological activities can be created to deal with various diseases. Or because its structure is in line with certain disease-related targets, and after rational derivation, it is expected to develop drugs for the treatment of diseases such as inflammation and tumors, for human health and well-being.

Or in the field of organic synthesis, it provides key structural units for the construction of complex organic molecules. Its unique double-ring structure and substituents can introduce specific spatial configurations and chemical activities for synthesis reactions, assisting chemists in constructing organic compounds with diverse structures and specific functions, and promoting the development of organic synthetic chemistry. It may also have potential uses in materials science and other related fields. It can be used as a key component in the construction of materials with special properties.

What are the precautions in the preparation of (1R, 4R, 5S) -4- (1,1-Dichloro-2,2,2-trifluoroethyl) -6,6-dimethyl-3-oxabicyclo (3.1.0) hexan-2-one?

When preparing (1R, 4R, 5S) -4- (1,1-dichloro-2,2,2-trifluoroethyl) -6,6-dimethyl-3-oxabicyclo (3.1.0) hexane-2-one, many precautions need to be taken with caution.

First, the selection of raw materials is the key. The purity and quality of the raw materials have a profound impact on the quality and yield of the product. The selected raw materials need to meet high purity standards. If there are many impurities, not only will the reaction efficiency be reduced, but also many side reactions may be derived, making it difficult to separate and purify the product.

Second, the precise control of the reaction conditions is indispensable. In terms of temperature, this reaction is extremely sensitive to temperature, and either high or low will affect the reaction process. If the temperature is too high, the reaction rate will increase, but the side reactions will also intensify; if the temperature is too low, the reaction rate will be slow and take a long time. At the same time, the pressure cannot be ignored, and the appropriate pressure can promote the smooth progress of the reaction in the expected direction. In addition, the reaction time also needs to be strictly controlled. If the time is too short, the reaction will not be fully functional; if the time is too long, the product decomposition or other side reactions may be triggered.

Third, the choice of solvent should not be underestimated. Different solvents have different effects on the reaction rate, selectivity and product stability. The selected solvent must be well compatible with the reactants and catalysts, and the solubility of the product is suitable for product separation and purification.

Fourth, the rational use of the catalyst is very important. The catalyst can effectively improve the reaction rate and selectivity. When using, it is necessary to pay attention to its type, dosage and timing of addition. If the amount of catalyst is too small, the catalytic effect is not good; if the amount is too large, it may increase the cost and may also cause unnecessary side reactions.

Fifth, the process of product separation and purification is crucial. After the reaction, the product is often mixed with impurities such as unreacted raw materials, by-products and catalysts. Choose a suitable separation method, such as distillation, extraction, chromatographic separation, etc., to ensure that the purity of the product is up to standard. During the purification process, pay attention to the influence of operating conditions on the stability of the product to avoid product loss or deterioration.