1-Butanone, 4- [4- (4-chlorophenyl) -4-hydroxy-1-piperidinyl] -1- (4-fluorophenyl) -, what is the chemical structure of hydrochloride?

This is a rather complex organic compound named 1-butanone, 4- [4- (4-chlorophenyl) -4-hydroxy-1-piperidinyl] -1 - (4-fluorophenyl) -, hydrochloride. To clarify its chemical structure, it can be analyzed according to the naming rules.

"1-butanone" indicates that the basic framework of the compound is butanone structure, that is, a chain structure containing four carbon atoms, and a carbonyl group (C = O) is attached to the first carbon atom.

"4- [4- (4-chlorophenyl) -4-hydroxy-1-piperidinyl]" shows a complex group attached to the 4th carbon atom of the butanone structure. In this group, the 4th position of the piperidine ring is connected with 4-chlorophenyl (that is, the 4th position of the benzene ring is replaced by a chlorine atom), and the 4th position of the piperidine ring is also connected with a hydroxyl group.

"1- (4-fluorophenyl) " indicates that a 4-fluorophenyl group is attached to the carbon atom connected to the carbonyl group at position 1 of the butanone structure (position 4 of the benzene ring is replaced by a fluorine atom).

Finally, "hydrochloride" indicates that the compound forms a salt with hydrochloric acid, or due to the presence of basic groups that can react with hydrochloric acid in the compound, such as nitrogen-containing basic groups that react with hydrochloric acid to form salts.

In this way, the structure of this compound consists of a butanone skeleton, which is connected with a substituent containing chlorine, fluorophenyl and hydroxypiperidinyl, and forms a hydrochloric salt.

What are the main physical properties of 1-Butanone, 4- [4- (4-chlorophenyl) -4-hydroxy-1-piperidinyl] -1- (4-fluorophenyl) -, hydrochloride?

1-Butanone, 4- [4- (4-chlorophenyl) -4-hydroxy-1-piperidyl] -1- (4-fluorophenyl) -hydrochloride, this is an organic compound. Its main physical properties, let me tell them one by one.

Looking at its properties, under normal circumstances, it may be a white to off-white crystalline powder. This is due to the characteristics of the intermolecular interaction of the compound, which makes it appear in this state. The powder has a fine texture and is easy to handle and use.

Talking about the melting point, this compound usually has a specific melting point range. The determination of melting point is a key indicator for identification and purity determination. After many experimental investigations, its melting point roughly falls in a certain range, which is determined by the forces between atoms in the molecular structure. Because the atoms in the molecule are arranged in an orderly manner and the mutual attractive force reaches a certain degree, at a certain temperature, the lattice structure disintegrates and then reaches the melting point.

In terms of solubility, in common organic solvents, their solubility varies. In some polar organic solvents, such as ethanol and acetone, there may be a certain solubility. Because the compound molecule has a certain polarity, hydrogen bonds or other intermolecular forces can be formed with polar solvent molecules, so it can be dissolved in it. However, in non-polar solvents, such as n-hexane, the solubility is very small, due to the difference in molecular forces between the two.

Furthermore, the stability of the compound is also an important physical property. Under normal temperature and pressure, dry environment, or can remain relatively stable. In case of high temperature, high humidity, or contact with specific chemicals, the molecular structure may change. In case of strong oxidants, strong acids, strong bases, or chemical reactions, the structure will be changed, which will affect its properties and uses.

In summary, the physical properties of 1-butanone, 4 - [4 - (4 - chlorophenyl) - 4 - hydroxy - 1 - piperidinyl] - 1 - (4 - fluorophenyl) - hydrochloride are of critical significance in its synthesis, storage and application.

1-Butanone, 4- [4- (4-chlorophenyl) -4-hydroxy-1-piperidinyl] -1- (4-fluorophenyl) -, hydrochloride What are the applications in the field of medicine?

This is a rather complex chemical substance named 1-butanone, 4- [4- (4-chlorophenyl) -4-hydroxy-1-piperidyl] -1- (4-fluorophenyl) -, hydrochloride. In the field of medicine, its use is crucial.

According to many books, such compounds containing specific phenyl and piperidyl structures often have unique pharmacological activities. Or can act on specific targets in the human body, such as certain neurotransmitter receptors or enzymes. The

cover can precisely interact with biomacromolecules due to the ingenious combination of chlorophenyl, fluorophenyl and hydroxypiperidinyl in its structure. Or it can regulate nerve conduction and improve neurological related diseases, such as depression, anxiety, etc.

And because of its special structure, it may affect cell signaling pathways, which may also have potential value in tumor treatment research. Or it can inhibit tumor cell proliferation and induce apoptosis, but more experimental verification is needed.

It may also play a role in the field of cardiovascular diseases. Or it can regulate the physiological functions of the cardiovascular system, such as affecting vascular tone, heart rate, etc., to achieve the purpose of treating related diseases. However, this is based on the speculation of its chemical structure and known similar compounds, and its practical application still needs to be confirmed by rigorous experimental and clinical studies.

1-Butanone, 4- [4- (4-chlorophenyl) -4-hydroxy-1-piperidinyl] -1- (4-fluorophenyl) -, what are the synthesis methods of hydrochloride?

The synthesis of 1-butanone, 4- [4- (4-chlorophenyl) -4-hydroxy-1-piperidyl] -1- (4-fluorophenyl) -hydrochloride is a crucial research in the field of organic synthesis. The synthesis of this compound often follows several common pathways.

First, the target molecule can be gradually constructed from the starting material through a multi-step reaction. First, a specific halogenated aromatic hydrocarbon, such as 4-chlorochlorobenzene and a compound containing piperidine structure, is formed by nucleophilic substitution reaction under the action of suitable bases and catalysts. This process requires fine regulation of reaction temperature, time and ratio of reactants to ensure efficient reaction and good selectivity.

Then, the intermediate and another halogenated aromatic hydrocarbon, such as 4-fluorobromobenzene, are again connected to the 4-fluorophenyl moiety through a similar nucleophilic substitution step. This step also requires strict control of the reaction conditions to prevent side reactions from occurring. After the key carbon-carbon bond is constructed, the hydroxyl functional group is introduced. The common method is to reduce the relevant carbonyl group to hydroxyl group through a suitable reduction reaction. For example, using reducing agents such as lithium aluminum hydride, operating in a low temperature and anhydrous environment, the formation of 4-hydroxyl groups is accurately achieved.

Finally, under suitable acidic conditions, the product is reacted with hydrogen chloride gas or hydrochloric acid solution to form the target hydrochloride salt. This salt formation step can effectively improve the stability and solubility of the compound, which is convenient for subsequent separation, purification and application.

Second, the strategy of reverse synthesis analysis can also be used. From the reverse derivation of the target product, it is disassembled into several simple structural units that are easy to obtain. According to the activity and reaction characteristics of each structural unit, a reasonable connection method and reaction sequence are designed. This method can plan the synthesis route more systematically and comprehensively, which helps to avoid potential synthesis difficulties and improve the overall synthesis efficiency.

In the synthesis of this compound, the monitoring of each step of the reaction and the purification of the product are extremely critical. TLC, NMR, mass spectrometry and other analytical methods are often used to monitor the reaction process in real time to ensure that each step of the reaction achieves the desired effect. The product can be purified by column chromatography, recrystallization and other classical methods to obtain high purity of the target product 1-butanone, 4- [4- (4-chlorophenyl) -4-hydroxy-1-piperidyl] -1- (4-fluorophenyl) -, hydrochloride.

What are the safety and toxicological data for 1-Butanone, 4- [4- (4-chlorophenyl) -4-hydroxy-1-piperidinyl] -1- (4-fluorophenyl) -, hydrochloride?

This is 1-butanone, 4- [4- (4-chlorophenyl) -4-hydroxy-1-piperidinyl] -1 - (4-fluorophenyl) -, hydrochloride and other drugs. However, its safety and toxicological data are not well known at present, and it is difficult to find them in ancient books.

The safety of Fu Ziming drugs requires knowing its impact on various organs of the human body, whether it has toxic and side effects, whether it causes disease, teratogenicity, carcinogenesis, etc. Toxicological data are related to the acute toxicity, chronic toxicity, subacute toxicity and other characteristics of the drug.

If you want to know the safety and toxicological data of this substance, you should follow the current method and use scientific experiments as the basis to conduct toxicity tests on animals, observe their reactions, and measure their half lethal dose and other key data. It is also necessary to conduct clinical trials in humans to observe its effects on the human body and observe whether there are any adverse reactions.

However, I have no exact data to report, so it is difficult to say in detail. If you want to know for sure, you can consult the latest medical books and research reports in the world, or consult physicians and scholars who are skilled in this field to obtain detailed and reliable information.