What is the chemical structure of 1-benzyl-4- (4-fluorophenyl) -1,2,3, 6-tetrahydropyridine, salt with p-toluenesulfonic acid?

The chemical structure of the salt of 1-benzyl-4- (4-fluorophenyl) -1,2,3,6-tetrahydropyridine and p-toluenesulfonic acid is composed of two parts.

The first part is 1-benzyl-4- (4-fluorophenyl) -1,2,3,6-tetrahydropyridine part, which has a pyridine ring, 1-position even benzyl, benzyl, benzyl, benzyl also, with a benzene ring connected to methylene. The 4-position is connected to 4-fluorophenyl, that is, the 4-position of the benzene ring has a fluorine atom substituted. And the 1,2,3,6-position of the pyridine ring is in a hydrogenated state, showing a partially hydrogenated state of an unsaturated ring structure.

The second is the p-toluenesulfonic acid part, the p-toluenesulfonic acid has a benzene ring, the methyl group is in the para-position, and the sulfonic acid group (-SO-H) is also connected to the benzene ring. In this salt structure, the nitrogen atom of 1-benzyl-4- (4-fluorophenyl) -1,2,3,6-tetrahydropyridine has lone pair electrons, and the sulfonic acid hydrogen of p-toluenesulfonic acid is acidic. The two act to form a salt. The nitrogen atom binds protons to form positive ions, the sulfonic acid group deprotons to form negative ions, and the anions and cations attract each other, forming the chemical structure of the salt as a whole and maintaining structural stability.

What are the main uses of 1-benzyl-4- (4-fluorophenyl) -1,2,3, 6-tetrahydropyridine, salt with p-toluenesulfonic acid?

A salt of 1-benzyl-4- (4-fluorophenyl) -1,2,3,6-tetrahydropyridine and p-toluenesulfonic acid. This compound is widely used. In the field of medicinal chemistry, it is often a key intermediate for the creation of new drugs. Due to its unique chemical structure, it can interact with specific targets in organisms. By modifying and optimizing its structure, it may be possible to develop drugs with excellent efficacy and less side effects to deal with a variety of diseases.

In the field of organic synthesis, this salt also plays an important role. It can be used as a catalyst to promote specific organic reactions. For example, in the synthesis of some complex cyclic compounds, its catalytic effect may improve the reaction efficiency and selectivity, achieving a synthesis path that is difficult to achieve by conventional methods, and assisting organic chemists in preparing various organic compounds with novel structures.

Furthermore, in the field of materials science, this compound may be used to prepare functional materials with specific properties due to its special physical and chemical properties. For example, in the preparation of optical materials, it can endow materials with unique optical properties, such as fluorescence properties, so that they can be used in optical display, biological imaging and many other aspects. In conclusion, 1-benzyl-4- (4-fluorophenyl) -1,2,3,6-tetrahydropyridine and p-toluenesulfonic acid salts have shown important application value in many scientific fields.

What is the synthesis method of 1-benzyl-4- (4-fluorophenyl) -1,2,3, 6-tetrahydropyridine, salt with p-toluenesulfonic acid?

To prepare 1 - benzyl - 4 - (4 - fluorophenyl) - 1, 2, 3, 6 - tetrahydropyridine, salt with p - toluenesulfonic acid, can be done according to the following ancient method.

The first raw material is to obtain benzyl halide, 4 - fluorostyrene and related pyridine derivatives. In a clean reactor, add an appropriate amount of benzyl halide and 4 - fluorostyrene, and then add an appropriate amount of base, such as potassium carbonate, to promote the reaction. Choose a suitable organic solvent, such as N, N - dimethylformamide, so that the raw materials can be evenly dispersed in it. < Br >
Heat up to a certain temperature, about 80-100 degrees Celsius, maintain this temperature, and when stirring for a few times, fully react the benzyl halide with 4-fluorostyrene to obtain an intermediate product.

Then, mix this intermediate product with the pyridine derivative, and add an appropriate amount of catalyst, such as a palladium catalyst. Continue the reaction at a suitable temperature and pressure. In this step, the temperature should be controlled at 60-80 degrees Celsius, and the pressure should be slightly higher than normal pressure. < Br >
After the reaction is completed, cool it, and purify the product by conventional separation means, such as column chromatography, to obtain 1-benzyl-4- (4-fluorophenyl) -1,2,3,6-tetrahydropyridine.

To form its salt with p-toluenesulfonic acid, take another container and dissolve 1-benzyl-4- (4-fluorophenyl) -1,2,3,6-tetrahydropyridine in an organic solvent such as ethanol. Slowly add the ethanol solution of p-toluenesulfonic acid and stir while adding. After the reaction is complete, cool and crystallize, filter with suction, and wash with ethanol several times to obtain pure 1-benzyl-4- (4-fluorophenyl) -1,2,3,6-tetrahydropyridine, salt with p-toluenesulfonic acid. The whole process needs to be handled with caution, paying attention to temperature, pressure and material ratio to obtain satisfactory results.

What are the physical properties of 1-benzyl-4- (4-fluorophenyl) -1,2,3, 6-tetrahydropyridine, salt with p-toluenesulfonic acid?

The physical properties of the salt of 1-benzyl-4- (4-fluorophenyl) -1,2,3,6-tetrahydropyridine and p-toluenesulfonic acid are as follows:

The properties of this compound are mostly solid at room temperature and pressure, but the specific appearance may vary due to different preparation processes and purity. Common white to quasi-white crystalline powders with finer texture.

When it comes to melting point, this salt has a specific melting point range, but the exact value depends on the experimental conditions and sample purity. Roughly speaking, more than a certain interval occurs in the phase transition, from solid state to liquid state, and this melting point range is of great significance for the identification and purity determination of compounds. < Br >
In terms of solubility, it exhibits unique properties in organic solvents. In polar organic solvents, such as methanol and ethanol, it often has a certain solubility and can form a homogeneous dispersion solution. In non-polar organic solvents, such as n-hexane and toluene, the solubility is relatively low. In water, due to the hydrophilicity of p-toluenesulfonate, this salt also has a certain tendency to dissolve, but the solubility is still closely related to factors such as temperature and solution pH.

In addition, the density of this salt is also an important physical property. Although the exact density value needs to be determined by precise experiments, its density may be closely related to the relative atomic mass and molecular structure of the constituent elements. < Br >
The physical properties of this compound are of great significance in many fields such as organic synthesis and drug development, which can help researchers gain a deeper understanding of its properties and provide a solid theoretical basis for related applications.

What is the price range of 1-benzyl-4- (4-fluorophenyl) -1,2,3, 6-tetrahydropyridine, salt with p-toluenesulfonic acid in the market?

I look at your question, but I am inquiring about the price range of 1 - benzyl - 4 - (4 - fluorophenyl) - 1, 2, 3, 6 - tetrahydropyridine, salt with p - toluenesulfonic acid in the market. However, the price of this product is difficult to determine.

The price of the product depends on many factors. First, the origin of the material. If the raw materials required for its preparation are easy to obtain and the supply is abundant, the price may be leveled; if the raw materials are rare and difficult to purchase, the price will rise. Second, the simplicity of the production method. If the preparation method is simple and convenient, and consumes less resources and manpower, the price will be inexpensive; if the preparation method is complicated, exquisite skills and expensive equipment are required, and the price will be high. Third, the supply and demand of the city. There are many people who ask for it, and there are few people who supply it, the price will rise; if the market is flooded and the demand is few, the price will fall.

Moreover, different regions and merchants have different pricing. In prosperous cities, business is prosperous, logistics is convenient, or there is competition and the price is excellent; in remote places, transportation is difficult, costs are increased, and the price may be high.

With common sense, without detailed market surveys, it is difficult to determine the price range. If you want to know the exact price, you should check the market conditions of chemical raw materials in detail, visit suppliers, or understand their approximate price range.