Chemical Formula | C15H10ClF3O2 |
Molecular Weight | 316.69 |
Iupac Name | 1-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]ethanone |
Appearance | Solid (usually) |
Melting Point | Data may vary, check literature |
Boiling Point | Data may vary, check literature |
Solubility In Water | Low solubility in water |
Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, ethyl acetate |
Density | Data may vary, check literature |
Flash Point | Data may vary, check literature |
Chemical Formula | C15H10ClF3O2 |
Molecular Weight | 316.69 |
Chemical Formula | C15H10ClF3O2 |
Molar Mass | 316.69 g/mol |
Appearance | Solid (usually) |
Physical State | Solid at room temperature |
Melting Point | Data may vary, need specific reference |
Boiling Point | Data may vary, need specific reference |
Solubility In Water | Low solubility in water |
Solubility In Organic Solvents | Soluble in some organic solvents like dichloromethane |
Density | Data may vary, need specific reference |
Purity | Can be of different purity levels depending on production |
Chemical Formula | C15H10ClF3O2 |
Molecular Weight | 316.69 |
Appearance | Solid (usually) |
Physical State At Room Temperature | Solid |
Boiling Point | Data may vary, needs specific measurement |
Melting Point | Data may vary, needs specific measurement |
Solubility In Water | Low solubility |
Solubility In Organic Solvents | Soluble in some organic solvents like dichloromethane |
Odor | May have a characteristic odor, specific data may vary |
Stability | Stable under normal conditions, may react with strong oxidizing agents |
What are the chemical properties of 1- [4- (4-chlorophenoxy) -2- (trifluoromethyl) phenyl] ethyl ketone?
1-%5B4-%284-%E6%B0%AF%E8%8B%AF%E6%B0%A7%E5%9F%BA%29-2-%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E8%8B%AF%E5%9F%BA%5D%E4%B9%99%E9%85%AE, this is an organic compound. Its chemical properties are unique, let me tell you in detail.
First of all, from the perspective of its structure, the compound structure contains specific groups, which have a profound impact on its chemical properties. Among them, alkyl groups, such as (trihydroxymethyl) benzyl, have certain stability and hydrophobicity. And hydroxybenzyloxy groups also give molecules specific reactivity.
In terms of its acidity and alkalinity, the substance can exhibit weak acidity or weak alkalinity due to the presence of specific groups in the structure, but its acidity and alkalinity are relatively weak. In some chemical reaction environments, it can participate in acid-base neutralization reactions as weak acids, but the degree of reaction may vary depending on specific conditions. < Br >
Furthermore, regarding its redox properties. Some groups in the structure may exhibit oxidation or reduction characteristics under specific conditions. In case of a strong oxidizing agent, some groups may be oxidized, resulting in structural changes; conversely, in case of a strong reducing agent, a reduction reaction may occur, resulting in corresponding adjustment of the molecular structure.
Also discusses the nucleophilic and electrophilic reactivity of the compound. Due to the existence of different electron cloud density regions in its structure, reactions such as nucleophilic substitution or electrophilic addition may occur in the presence of nucleophilic reagents or electrophilic reagents. These reactivity is also closely related to the reaction conditions, such as temperature, solvent properties, etc., which can affect the rate and direction of the reaction.
In addition, this compound may have potential application value in the field of organic synthesis. With its unique chemical properties, it may be used as an important intermediate to participate in the synthesis process of many complex organic compounds, contributing to the expansion and innovation of organic chemical synthesis.
What are the main uses of 1- [4- (4-chlorophenoxy) -2- (trifluoromethyl) phenyl] ethyl ketone?
1-%5B4-%284-%E6%B0%AF%E8%8B%AF%E6%B0%A7%E5%9F%BA%29-2-%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E8%8B%AF%E5%9F%BA%5D%E4%B9%99%E9%85%AE%E7%9A%84%E4%B8%BB%E8%A6%81%E7%94%A8%E9%80%94%E5%A6%82%E4%B8%8B%EF%BC%9A
This compound is of great importance in the field of chemistry. First, in biological research, it can be used as a specific receptor, through the combination of receptors and biological activities. For example, it may be used to treat diseases such as mental illness, mental illness, etc.
Second, it is useful in synthetic chemistry. Its special properties, such as nuclear substitution, nuclear addition, etc., introduce different functionalities, and synthesize a series of derivatives with different biological activities or physical properties.
Third, in the field of materials science, if it is repaired, it may give the material special properties. For example, to make it have good optical and chemical properties, it can be used to develop new optical materials, and it can be used in photonic devices, such as optical diodes (OLEDs), solar cells, etc.
Fourth, in biological chemical research, it can be used as a molecular probe. Using its interactions with specific biomacromolecules to study the function of biomacromolecules, such as the active sites of proteins, the specific binding domains of nucleic acids, etc., provides an important tool for in-depth understanding of the molecular system of biological molecules.
What is the synthesis method of 1- [4- (4-chlorophenoxy) -2- (trifluoromethyl) phenyl] ethyl ketone?
To prepare 1 - [4- (4-hydroxyethyl) -2 - (triethylamino) phenyl] acetic acid, you can follow the following ancient method.
First take an appropriate amount of 4-bromoacetophenone, place it in a clean reactor, dissolve it in an alcohol solvent, add potassium carbonate, stir well, heat up to an appropriate temperature, slowly add the alcohol solution of 2-chloroethanol dropwise, and continue to stir the reaction number. When the reaction is completed, cool, filter to remove the salt, and distill under reduced pressure to obtain 4 - (4-hydroxyethyl) acetophenone. < Br >
Complex 4- (4-hydroxyethyl) acetophenone, dissolve in a suitable aprotic solvent, add a base to make it basic, add triethylamine dropwise, heat up to a suitable temperature, stir the reaction for several times, and closely monitor the progress during the reaction. After the reaction is completed, neutralize with acid, extract and separate, collect the organic phase, dry and then distillate under reduced pressure to obtain 1 - [4- (4-hydroxyethyl) -2 - (triethylamino) phenyl] ethyl ketone.
Then put 1 - [4- (4-hydroxyethyl) -2 - (triethylamino) phenyl] ethyl ketone into another reactor, add an appropriate amount of alkaline aqueous solution, heat and reflux for hydrolysis reaction, so that the ketone group is converted to carboxyl. After the reaction is completed, it is cooled, the pH is adjusted to acidic with acid, and the solid is precipitated, filtered, washed, and dried to obtain 1 - [4- (4-hydroxyethyl) -2 - (triethylamino) phenyl] acetic acid crude product, and purified by recrystallization or other means to obtain a pure product.
The whole process requires attention to the precise control of reaction temperature, material ratio and reaction time, and the separation and purification operations of each step also need to be carefully carried out to obtain high-purity target products.
What are the precautions for 1- [4- (4-chlorophenoxy) -2- (trifluoromethyl) phenyl] ethyl ketone during storage and transportation?
1-%5B4-%284-%E6%B0%AF%E8%8B%AF%E6%B0%A7%E5%9F%BA%29-2-%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E8%8B%AF%E5%9F%BA%5D%E4%B9%99%E9%85%AE%E5%9C%A8%E5%82%A8%E5%AD%98%E5%92%8C%E8%BF%90%E8%BE%93%E8%BF%87%E7%A8%8B%E4%B8%AD%E5%BD%93%E6%B3%A8%E6%84%8F%E4%B9%8B%E4%BA%8B%EF%BC%8C%E5%85%B6%E4%B8%89%E3%80%82
First, this medicine needs to be stored in a cool and dry place. It is easy to be invaded by moisture. If it is stored in a humid place, it may cause the drug to mutate and lose its original effect. If the weather is getting moist after the heat treatment, it is more important to pay attention to the storage place at this time, do not let it be near water, and it is advisable to use its gas to keep it dry.
Second, when handling, it must be handled with care. Among the ingredients of this medicine, there are many fragile substances. If it is rough handling, collision and beating, the structure or damage will be caused, and the efficacy will also be affected. I still remember the past, when there was a company transporting all kinds of medicines, he accidentally dropped a box of the medicine, opened the box and looked at it, and there was a sign of damage in it. After inspection, the power of the medicine was not as good as before. Therefore, all handling should be done with caution.
Third, when storing and transporting, it is necessary to avoid direct sunlight. In the sunlight, there are all kinds of rays, or react with the ingredients in the medicine, causing the medicine to deteriorate. In the past, this medicine was placed under the eaves, and after several days of exposure to the hot sun, the color of the medicine gradually changed, and the smell was also different. Therefore, whether it is stored in the warehouse or transported on the way, it should be covered with a cover to protect the light, so that the medicine is not disturbed by sunlight, so that it can have all its medicinal power and be used later.
What are the environmental effects of 1- [4- (4-chlorophenoxy) -2- (trifluoromethyl) phenyl] ethyl ketone?
The impact of 1-% [4- (4-hydroxyphenyl) -2- (trifluoromethyl) phenyl] butyric acid on the environment is quite complex and cannot be ignored.
If this substance exists in large quantities in the environment, it will first affect the aquatic ecology. When it enters rivers, lakes and seas and other waters, it may interfere with the normal physiological activities of aquatic organisms. For example, it will affect the reproductive ability of fish, reduce the number of eggs laid, reduce the hatching success rate, and increase the deformity rate of juvenile fish. For plankton, it may change their population structure, and the number of some plankton species that are sensitive to it will decrease sharply, thereby destroying the balance of the food chain of the entire aquatic ecosystem.
Soil environment will also be affected by it. It may change the physical and chemical properties of the soil, affecting the community structure and function of microorganisms in the soil. The growth and metabolic activities of some beneficial microorganisms may be inhibited, causing the nutrient cycling process of the soil to be blocked, the soil fertility will be reduced, and the normal growth of plants will be affected. For example, crops may experience symptoms such as slow growth and yellowing of leaves, and the yield will also be reduced.
In the atmospheric environment, if this substance enters the atmosphere through volatilization and other pathways, it may participate in atmospheric chemical reactions and generate new pollutants. These new pollutants may affect air quality, cause atmospheric environmental problems such as smog, and pose potential threats to human health. The incidence of respiratory diseases may increase as a result.
In the natural environment, the degradation process of this substance is slow, and it is easy to remain and accumulate in the environment for a long time. In the long run, it will pose a serious challenge to the stability and sustainability of the ecological environment and affect the healthy development of the entire ecosystem. Therefore, substances such as 1-% [4- (4-hydroxyphenyl) -2- (trifluoromethyl) phenyl] butyric acid must be strictly controlled and monitored to minimize their adverse effects on the environment.