What are the main application fields of 1- (2,2,3,3,3,4,4,4-heptafluorobutoxy) -propyl-2-ol

1 - (2, 2, 3, 3, 3, 4, 4 - heptafluoroisopropanol) -nonene-2-ene has a wide range of application fields.

This compound is widely used in the field of organic synthesis. It has a unique structure and can be used as a key intermediate in the construction of complex organic molecules. Through specific chemical reactions, it can be combined with many reagents to shape various novel organic structures, laying the foundation for the creation of new drugs and the development of new materials.

In the field of pharmaceutical chemistry, it also plays an important role. Because of its characteristics, it may participate in the synthesis process of active pharmaceutical ingredients. Drug developers often use it to participate in reactions to obtain compounds with specific pharmacological activities, and then screen for new drugs with better efficacy and fewer side effects.

In the field of materials science, 1 - (2,2,3,3,3,4,4, 4 - heptafluoroisopropanol) -non-2 - ene also plays a role. It can be introduced into polymer materials through chemical reactions to give the materials special properties such as chemical resistance and low surface energy, thereby expanding the application range of materials, such as the preparation of high-end coatings, special functional films, etc.

In the fine chemical industry, this compound is also an important raw material. It can be used to synthesize various fine chemicals, such as special fragrances, additives, etc., to improve the quality and performance of fine chemical products and meet the needs of different industries for special chemicals.

What are the physical properties of 1- (2,2,3,3,3,4,4,4-heptafluorobutoxy) -propyl-2-ol?

1 - (2, 2, 3, 3, 3, 4, 4 - heptacyanine) -non-2 - alkyne is a rare substance in the world, and its physical properties are particularly unique.

This alkyne compound is often a colorless to light yellow oily liquid with a certain fluidity under normal temperature and pressure. Its melting point is quite low, about minus tens of degrees Celsius, making it difficult to solidify in common low temperature environments, and it can still maintain a liquid state, like a flexible firefly. The boiling point is relatively high, and it needs to reach a specific high temperature to boil and gasify. This property makes it stable in liquid state under normal heating conditions.

When it comes to density, it is heavier than water. If placed in water, it is like sinking gold to the bottom, quietly lying under the water layer. Its solubility is also unique. It can be well miscible in organic solvents such as ethanol and ether, just like water and milk, but it is extremely difficult to dissolve in water. The two seem to be distinct and difficult to blend.

As for volatility, it is relatively weak, and it is not easy to evaporate and dissipate quickly in the air. It can maintain its own shape and properties for a certain period of time. And this substance has a certain refractive property. When light passes through, it will undergo a unique refraction phenomenon, which is like a gem flashing with a strange luster. It is impressive and cannot help but be overwhelmed by its physical properties.

Is the chemical property of 1- (2,2,3,3,3,4,4,4-heptafluorobutoxy) -propyl-2-ol stable?

1-%282%2C2%2C3%2C3%2C3%2C4%2C4%2C4-%E4%B8%83%E6%B0%9F%E4%B8%81%E6%B0%A7%E5%9F%BA%29-%E4%B8%99-2-%E9%86%87%E7%9A%84%E5%8C%96%E5%AD%A6%E6%80%A7%E8%B4%A8%E7%A8%B3%E5%AE%9A%E5%90%97%3F chemical substances such as "1- (2,2,3,3,3,3,4,4,4-heptafluoro-hydroxy) -non-2-alkyne" involved in this question, their chemical properties are relatively stable.

In the molecular structure of this substance, the heptafluoro-hydroxy group is connected to the main chain of non-2-alkyne. The fluorine atom has strong electronegativity, which can change the distribution of molecular electron clouds and form a stable electronic structure. And although the alkynyl group has a certain reactivity, under certain conditions, the electronic effect and steric resistance of the surrounding groups can limit its activity to a certain extent.

Furthermore, the fluorine atom in the heptafluoro-hydroxy group can reduce the electron cloud density of the carbon atom connected to it through the induction effect, which in turn affects the electron cloud distribution of the alkynyl group, so that the entire molecular structure tends to be stable. Coupled with the steric resistance effect generated by the spatial structure of the substance, it is difficult for foreign reagents to approach the reaction check point, further improving its chemical stability. Therefore, in general, 1- (2,2,3,3,3,4,4-heptafluoro-hydroxy) -non-2-alkyne is chemically stable under common conditions.

What are the preparation methods of 1- (2,2,3,3,3,4,4,4-heptafluorobutoxy) -propyl-2-ol?

To prepare 1 - (2,2,3,3,3,4,4, 4 - heptafluorobutyl) -nonono-2 - alkyne, the preparation method is as follows:

can be coupled with fluorohalogenated hydrocarbons by suitable alkynes under basic conditions and catalysts. For example, 2 - nonyne is used as the starting material, in the presence of a base (such as potassium carbonate, etc.), with 2,2,3,3,4,4,4 - heptafluorobutyl halide (such as 2,2,3,3,3,4,4, 4 - heptafluorobutyl bromide) in an organic solvent (such as N, N - dimethylformamide, etc.), at an appropriate temperature (such as 60 - 80 ℃) reaction. The role of a base is to capture hydrogen from alkynes to form carbon anions, enhance their nucleophilicity, and then undergo nucleophilic substitution reactions with fluorohalogenated hydrocarbons.

Or use a strategy of gradually building carbon chains. First synthesize fragments containing part of the target structure, for example, prepare intermediates containing alkynyl groups at one end and suitable functional groups at the other end, and then connect them to fluorine-containing fragments through suitable reactions (such as nucleophilic addition, condensation, etc.). For example, alcohols containing nonyne fragments can be synthesized first, converted into halogenates by halogenating reagents, and then reacted with metal-organic reagents containing 2,2,3,3,3,4,4, 4-heptafluorobutyl (such as Grignard reagents, etc.) to realize the connection of carbon chains and the construction of target products.

In addition, the cross-coupling reaction catalyzed by transition metals can also be considered. Transition metals such as palladium and copper are used as catalysts, and ligands (such as phosphine ligands, etc.) are used to assist to promote the efficient coupling of alkynes and fluorohalogenated hydrocarbons. In the reaction system, transition metals and ligands form active catalytic centers to activate the substrates, reduce the activation energy of the reaction, and make the reaction proceed under relatively mild conditions, thereby improving the selectivity and yield of the reaction to achieve the preparation of 1- (2,2,3,3,3,4,4-heptafluorobutyl) -non-2-yne.

What is the price range of 1- (2,2,3,3,3,4,4,4-heptafluorobutoxy) -propyl-2-ol in the market?

I look at what you are asking, and I seem to be asking about the price range of (2,2,3,3,3,4,4,4-heptafluorobutylamino) -nonene-2-ene in the market. However, in order to clarify its price, many reasons need to be observed.

First, the supply and demand of this compound. If there are many people in the world who want it, but there are few products, the price will be high; if the supply exceeds the demand, the price will decrease.

Second, its preparation is difficult and easy. If the preparation method is complicated, the materials used are expensive, time-consuming and laborious, the cost will be high and the price will be high; if the preparation is convenient and the cost is low, the price is expected to drop.

Third, the state of market competition. If various companies compete to produce this product and compete with each other for the market, it is to attract customers, or to reduce the price; if it is an exclusive monopoly, the price may be set by it.

Fourth, the current situation changes. Such as natural and man-made disasters, changes in government orders, can affect its production and transportation, resulting in cost fluctuations, and the price will also change.

With common sense, such fine chemicals, if there is no accident, the price may be in the middle and high position. Because of their complex structure, the preparation may require exquisite methods, and the raw materials used may be quite expensive. However, it is difficult to determine its specific price range. It is necessary to carefully observe the market and interview various industry players before we can get a more accurate number. Or from tens of gold to hundreds of gold per gram, this is just speculation, and the truth should be subject to market conditions.