What is the chemical structure of Potassium 2 ', 4' -difluoro-4-hydroxy [1,1 '-biphenyl] -3-carboxylate?

This is called "Potassium 2 ', 4' -difluoro-4-hydroxy [1,1 '-biphenyl] -3-carboxylate". Looking at the naming, it can be seen that this compound uses biphenyl as the parent nucleus. "2', 4 '-difluoro" indicates that there is a fluorine atom attached to each of the 2' and 4 'positions of a benzene ring in the biphenyl structure; "4-hydroxy" means that the 4-position of another benzene ring is connected with a hydroxyl group; "3-carboxylate", that is, the 3-position of this benzene ring is connected with a carboxyl group and is in the form of a potassium salt. Its structure is described as follows: two benzene rings are connected to form a biphenyl skeleton. One benzene ring has fluorine atom substitution at 2 'and 4', the other benzene ring has a hydroxyl group at 4 positions, and the carboxyl group at 3 positions forms a salt with potassium ions. This structure endows the compound with unique chemical properties and potential applications, and may have important value in organic synthesis, medicinal chemistry and other fields.

What are the main uses of Potassium 2 ', 4' -difluoro-4-hydroxy [1,1 '-biphenyl] -3-carboxylate

Potassium 2 ', 4' -difluoro-4-hydroxy [1,1 '-biphenyl] -3-carboxylate is widely used. This compound is used in the field of medicine, or can be used to create new drugs. According to the old saying, in the medical system, if you want to make a good medicine, this potassium salt may be an exquisite choice, helping physicians to achieve the effect of treating diseases and saving people.

In the field of materials science, it also has unique functions. It can contribute to the development of new materials. For example, in the preparation of some special materials, it can be used as a key raw material. Just like the ancient creation, this potassium salt is like an indispensable material, helping craftsmen to create exquisite and sturdy utensils.

In agriculture, it may be beneficial to plant growth regulation. Just like farming in ancient times, there are things that can help crops thrive, and this potassium salt may affect the physiological process of plants, regulate their growth, and achieve the hope of a bumper harvest.

And in the field of chemical research, it is often used as a reactant or catalyst. Just like alchemy in ancient times, this potassium salt can promote the smooth progress of reactions in the "cauldron" of various chemical reactions, providing chemists with help to explore the unknown chemical world.

What is the preparation method of Potassium 2 ', 4' -difluoro-4-hydroxy [1,1 '-biphenyl] -3-carboxylate?

To prepare 2 ', 4' -difluoro-4-hydroxy- [1,1 '-biphenyl] -3-carboxylic acid potassium salt, you can follow the following method.

Take 2', 4 '-difluoro-4-methoxy- [1,1' -biphenyl] -3-carboxylic acid as the starting material and place it in an appropriate reaction vessel. Add an appropriate amount of strong base, such as potassium hydroxide alcohol solution, alcohol as the solvent, common ethanol and methanol can be used. Warm up to a suitable temperature, about 60-80 degrees Celsius, and carry out hydrolysis reaction. During this process, the methoxy group is left under the action of the base to form the corresponding phenolic hydroxyl group, and the carboxyl group is combined with potassium ions. The reaction is carried out for several hours, during which the progress is observed by thin-layer chromatography or other suitable monitoring means until the raw material is completely converted.

After the reaction is completed, the reaction system is cooled to room temperature, and then separated and purified. The solvent can be removed by vacuum distillation first, and the residue is dissolved in an appropriate amount of water, and then extracted with an organic solvent such as ether to remove unreacted impurities and by-products. The aqueous phase is acidified and adjusted to a suitable pH value, so that 2 ', 4' -difluoro-4-hydroxy - [1,1 '-biphenyl] -3-carboxylic acid is precipitated, and the precipitation is filtered and collected. The precipitation is then redissolved in an appropriate amount of alkali solution, such as potassium hydroxide aqueous solution, and the amount is controlled to form a potassium carboxylate salt. Finally, through concentration, crystallization and other operations, pure 2 ', 4' -difluoro-4-hydroxy- [1,1 '-biphenyl] -3-carboxylic acid potassium salt can be obtained.

There are other methods, which can be prepared by a series of reactions such as nucleophilic substitution starting from the corresponding halogen. However, this route step may be more complicated, the reaction conditions of each step need to be carefully regulated, and the raw material acquisition may be inconvenient. In comparison, the above method of hydrolysis of methoxy compounds is relatively simple and the yield is considerable, which is more suitable for the preparation of 2', 4 '-difluoro-4-hydroxy- [1,1' -biphenyl] -3-carboxylic acid potassium salt.

What are the physicochemical properties of Potassium 2 ', 4' -difluoro-4-hydroxy [1,1 '-biphenyl] -3-carboxylate

Potassium-2 ', 4' -difluoro-4-hydroxy [1,1 '-biphenyl] -3-carboxylate is also an organic compound. Its physical and chemical properties are quite important, related to the application and characteristics of this compound.

In terms of its physical properties, the properties of this compound are usually solid, but its specific color state may vary depending on purity and crystallization. Its melting point is one of the key physical constants. The level of melting point is affected by the intermolecular force. The presence of fluorine atoms in the molecule can strengthen the intermolecular force and increase the melting point. Its solubility cannot be ignored. In organic solvents, such as ethanol, acetone, etc., it may have a certain solubility. Due to the principle of similar miscibility, the organic structure of the compound is similar to the molecular structure of organic solvents. In water, its solubility may be limited. Although there are carboxylate groups in the molecule that can form hydrogen bonds with water, hydrophobic parts such as aromatic rings and fluorine atoms also exist, limiting their dissolution in water.

In terms of its chemical properties, carboxylate groups have typical chemical activities. First, they can react with acids and be converted into corresponding carboxylic acids through protonation. This reaction is quite useful in regulating the acidity and alkalinity and chemical morphology of compounds. Second, the hydroxyl group is also an active group, which can participate in the esterification reaction and form ester compounds with alcohols under appropriate catalysts and conditions. This reaction is a common path for building ester bonds in organic synthesis. Furthermore, although the fluorine atom in the molecule is relatively stable, it may also participate in the substitution reaction under specific strong reaction conditions. Due to the high electronegativity of fluorine atoms, it can affect the electron cloud density of neighboring atoms and change the reactive site of the molecule.

The physicochemical properties of potassium-2 ', 4' -difluoro-4-hydroxy [1,1 '-biphenyl] -3-carboxylate are of great significance in the fields of organic synthesis, materials science and medicinal chemistry, affecting the efficiency and direction of its application.

Potassium 2 ', 4' -difluoro-4-hydroxy [1,1 '-biphenyl] -3-carboxylate, what is the price range in the market?

Today, I have a question about the price range of potassium 2 ', 4' -difluoro-4-hydroxy [1,1 '-biphenyl] -3-carboxylate in the market. However, this is a very new and specialized chemical, and I can't find it in the classics and market conditions.

If you want to know its price, or you should find various chemical dealers in the city. Market chemical prices often vary depending on quality, quantity, supply and demand, and provenance. Or you can go to a store specializing in fine chemicals to inquire about their prices. < Br >
Or in the books and records related to the chemical industry, or there is any clue about the price of this product, but with the current limit, it is difficult for me to determine the price range. It is still necessary to inquire from many parties in the field of modern business and chemical industry before we can obtain a more accurate price range.