Chemical Name | N-(3-{[5-(4-chlorophenyl)-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide |
Chemical Formula | C30H20Cl3F2N3O4S |
Molecular Weight | 658.82 g/mol |
Physical State | Solid (predicted) |
Appearance | Off - white to pale yellow solid (estimated) |
Solubility In Water | Low solubility (due to its non - polar nature with many hydrophobic groups) |
Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform (hydrophobic molecule) |
Logp | High (lipophilic, due to multiple aromatic and halogen - containing groups) |
Chemical Name | N-(3-{[5-(4-chlorophenyl)-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide |
Chemical Name | N-(3-{[5-(4-chlorophenyl)-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide |
Chemical Name | N-(3-{[5-(4-chlorophenyl)-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide |
What is the chemical structure of N- (3- {[5- (4-chlorophenyl) -1- (2,6-dichlorobenzoyl) -1H-pyrrolo [2,3-b] pyridin-3-yl] carbonyl} -2,4-difluorophenyl) propane-1-sulfonamide?
This is a rather complex nomenclature for organic compounds. To clarify its chemical structure, it is necessary to analyze it according to the nomenclature of organic chemistry. "N- (3- {[5- (4-chlorophenyl) -1 - (2,6-dichlorobenzoyl) -1H-pyrrolido [2,3-b] pyridine-3-yl] carbonyl} -2,4-difluorophenyl) propane-1-sulfonamide". < Br >
Starting from "propane-1-sulfonamide", which is the basic skeleton of the compound, the sulfonamide group is attached to the first carbon of propane. Looking at "N -" again, it shows that the substituent is attached to the nitrogen atom.
" (3 - {[5- (4-chlorophenyl) -1 - (2,6-dichlorobenzoyl) -1 - (2,6-dichlorobenzoyl) -1H -pyrrolio [2,3 - b] pyridine-3-yl] carbonyl} -2, 4 -difluorophenyl) " This part can be separated and separated. Among them, " (3- {[...] carbonyl} -2,4-difluorophenyl) ", it can be seen that the 3rd position of 2,4-difluorophenyl is connected with a carbonyl-containing group. And the carbonyl group is connected to "[5- (4-chlorophenyl) -1 - (2,6-dichlorobenzoyl) -1H-pyrrolido [2,3-b] pyridine-3-yl]", which also contains many structures. The 5th position is connected with 4-chlorophenyl, and the 1st position is connected with 2,6-dichlorobenzoyl, all of which are at the specific position of 1H-pyrrolido [2,3-b] pyridine.
In summary, this compound has a complex structure, which is formed by a variety of groups connected in a specific way. The construction of its chemical structure is like a delicate puzzle, and each part fits closely according to the rules of organic chemistry.
What are the physical properties of N- (3- {[5- (4-chlorophenyl) -1- (2,6-dichlorobenzoyl) -1H-pyrrolo [2,3-b] pyridin-3-yl] carbonyl} -2,4-difluorophenyl) propane-1-sulfonamide?
This is an organic compound named N- (3- {[5- (4-chlorophenyl) -1- (2,6-dichlorobenzoyl) -1H-pyrrolido [2,3-b] pyridine-3-yl] carbonyl} -2,4-difluorophenyl) propane-1-sulfonamide. Looking at the structure of this compound, it has specific physical and chemical properties.
In terms of physical properties, such organic compounds are usually in a solid state. Due to the existence of various forces between molecules, such as van der Waals force, hydrogen bonds, etc., the molecules are arranged in an orderly manner and appear in a solid state. However, the specific melting point needs to be accurately determined by experiments, because different substituents in the molecule will affect the strength of intermolecular forces, thereby changing the melting point. Its color may be white to off-white, and most organic compounds containing aromatic rings look like this, due to the light absorption and reflection characteristics of the aromatic ring structure.
In terms of solubility, the compound contains many polar groups, such as sulfonamido and carbonyl, so that it may have a certain polarity. In polar organic solvents, such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), it may have good solubility. Due to the principle of "similar miscibility", polar solvents and polar compounds can form favorable interactions. However, in non-polar solvents, such as n-hexane, the solubility may be poor.
In addition, the molecular structure of the compound contains multiple aromatic rings and heterocycles, which endows it with certain stability. The conjugated system of aromatic rings can disperse electron clouds, enhance molecular stability, and make it less prone to chemical reactions. However, there are also active check points in the molecule, such as carbon atoms of carbonyl groups are electrophilic, or can participate in reactions such as nucleophilic addition, which affects their chemical stability, depending on the reaction conditions.
What are the main uses of N- (3- {[5- (4-chlorophenyl) -1- (2,6-dichlorobenzoyl) -1H-pyrrolo [2,3-b] pyridin-3-yl] carbonyl} -2,4-difluorophenyl) propane-1-sulfonamide?
N- (3- {[5- (4-chlorophenyl) -1- (2,6-dichlorobenzoyl) -1H-pyrrolido [2,3-b] pyridine-3-yl] carbonyl} -2,4-difluorophenyl) propane-1-sulfonamide, which is a fine organic compound. Looking at its complex structure, it is cleverly spliced from multiple groups and has important uses in many fields.
In the field of pharmaceutical research and development, it may be used as a lead compound. Due to its unique structure, it contains a variety of active groups and can precisely bind to specific targets in organisms. After in-depth research and modification, it is expected to develop new drugs for treating specific diseases. For example, for some inflammatory diseases, by virtue of its structural characteristics, it can effectively regulate inflammation-related signaling pathways and exert anti-inflammatory effects; or it has a targeted effect on specific tumor cells, contributing to the development of anti-cancer drugs.
In the field of materials science, it may have special properties. Because it contains a variety of aromatic rings and special functional groups, it may endow materials with unique electrical and optical properties. After rational design and processing, it may be used to manufacture organic optoelectronic materials, such as organic Light Emitting Diode (OLED), organic solar cells, etc., injecting new vitality into the development of materials science.
In the field of agricultural chemistry, it may also show unique effects. In view of its structural characteristics, or have inhibitory or killing effects on some crop pests and pathogens, it is expected to be developed into a new type of pesticide, which will contribute to ensuring crop yield and quality.
In short, N- (3- {[5- (4-chlorophenyl) -1- (2,6-dichlorobenzoyl) -1H-pyrrolido [2,3-b] pyridine-3-yl] carbonyl} -2,4-difluorophenyl) propane-1-sulfonamide has great potential application value in medicine, materials, agriculture and other fields due to its unique structure, and needs to be further explored and developed.
What are the synthesis methods of N- (3- {[5- (4-chlorophenyl) -1- (2,6-dichlorobenzoyl) -1H-pyrrolo [2,3-b] pyridin-3-yl] carbonyl} -2,4-difluorophenyl) propane-1-sulfonamide?
The synthesis of N- (3- {[5- (4-chlorophenyl) -1- (2,6-dichlorobenzoyl) -1H-pyrrolido [2,3-b] pyridine-3-yl] carbonyl} -2,4-difluorophenyl) propane-1-sulfonamide has been followed by ancient methods. The synthesis of this compound requires detailed review of the characteristics of each functional group.
To form this compound, you can first use 5- (4-chlorophenyl) -1- (2,6-dichlorobenzoyl) -1H-pyrrolido [2,3-b] pyridine-3-carboxylic acid as the starting material, and use an appropriate condensing agent, such as carbodiimide, to condensate with 2,4-difluoroaniline to obtain the corresponding amide intermediate. During this process, attention should be paid to the control of the pH, temperature and time of the reaction to prevent side reactions.
Then, the amide intermediate is reacted with propane-1-sulfonyl chloride in an alkaline environment. The choice of base is crucial, such as triethylamine, pyridine, etc. The dosage and reaction conditions of the commonly used ones will affect the yield and purity of the product. This step aims to introduce sulfonyl chloride into the amide intermediate to build the basic structure of the target compound.
Or, another way can be found. First, 2,4-difluorobenzaldehyde is condensed with suitable pyrrole derivatives to construct the parent nuclear structure of pyrrolido [2,3-b] pyridine, and then 4-chlorophenyl and 2,6-dichlorobenzoyl are introduced, and finally propane-1-sulfonamide is connected. Although this path is a little complicated, the precise regulation of each step of the reaction may lead to higher purity products.
Synthesis requires insight into the reaction mechanism of each step and careful optimization of the reaction conditions to obtain satisfactory results. When operating, be sure to follow the norms of chemical experiments and pay attention to safety to ensure the smooth synthesis process.
What are the market prospects for N- (3- {[5- (4-chlorophenyl) -1- (2,6-dichlorobenzoyl) -1H-pyrrolo [2,3-b] pyridin-3-yl] carbonyl} -2,4-difluorophenyl) propane-1-sulfonamide?
There is now a thing named N- (3- {[5- (4-chlorophenyl) -1- (2,6-dichlorobenzoyl) -1H-pyrrolido [2,3-b] pyridine-3-yl] carbonyl} -2,4-difluorophenyl) propane-1-sulfonamide. However, this thing is in the city, and the future is uncertain.
To observe the appearance of various new things, its future often depends on various factors. First, it is about utility. If this medicine has outstanding effect when it is used to heal diseases and remove diseases, it can heal diseases and relieve the suffering of the people, it must be valued by doctors, and the patients need it, and the market prospect should be bright. However, if its effect is mediocre, or there are alternatives, cheap and with the same effect, it will be difficult to stand out.
Second, it depends on safety. The way to use medicine, safety comes first. If this thing is in the human body, there are no obvious toxic and side effects, and it does not cause all kinds of discomfort, it can be trusted by doctors and patients. On the contrary, if the safety is worrying, the longitudinal effect can be said, and it is difficult to survive in the city for a long time.
Third, it is about promotion. Although it is effective and safe, there are few people who know it, and it is difficult to develop grand plans. It is necessary to rely on strong promotion to make doctors and patients aware of its ability, so that it can be widely distributed in the city.
As for N- (3- {[5- (4-chlorophenyl) -1- (2,6-dichlorobenzoyl) -1H-pyrrolido [2,3-b] pyridine-3-yl] carbonyl} -2,4-difluorophenyl) propane-1-sulfonamide, its prospects depend on these numbers. Or because of its extraordinary utility, safety and promotion, it is well-known in the market; or because of the lack of a certain end, it is not among the things. The market is impermanent, and only by strength and opportunity can we know the truth.