What are the main application fields of (5R) -3- (3,4-difluoro-2-methoxyphenyl) -4,5-dimethyl-5- (trifluoromethyl) furan-2-one?

(5R) -3- (3,4-diene-2-methoxyphenyl) -4,5-dimethyl-5- (trienomethyl) imidazole-2-one has important applications in many fields.

In the field of medicinal chemistry, such compounds containing imidazolone structures often exhibit unique biological activities. Imidazolone rings can interact with specific targets in organisms, such as certain enzymes or receptors, through hydrogen bonds, van der Waals forces, etc., to affect their physiological functions. Like (5R) -3- (3,4-diene-2-methoxyphenyl) -4,5-dimethyl-5- (trienomethyl) imidazole-2-one, or because of its structure The hydrophobicity and steric hindrance imparted by phenyl, methyl and other groups are precisely matched with the target, and then exert anti-inflammatory and anti-tumor effects, providing key lead compounds for innovative drug development.

Within the scope of materials science, this compound can be used as a functional monomer or additive. The imidazolone structure can participate in the polymerization reaction and endow materials with special properties. If it is introduced into polymer materials, or to improve the thermal stability, mechanical properties and chemical stability of materials. Because of its unsaturated bonds in the structure, it can initiate polymerization, form cross-linking structures, and improve the strength and durability of materials, and is used in high-performance engineering plastics, coatings, etc.

In the field of organic synthetic chemistry, it is an important synthetic intermediate. Its complex structure contains multiple activity check points, which can be modified and converted through various organic reactions. Using the reactivity of its methoxy group, alkenyl group and other groups, nucleophilic substitution, addition and other reactions can be carried out to construct more complex and diverse organic molecules, providing a key cornerstone for organic synthetic chemistry and assisting the creation and development of new organic compounds.

What are the synthesis methods of (5R) -3- (3,4-difluoro-2-methoxyphenyl) -4,5-dimethyl-5- (trifluoromethyl) furan-2-one?

To prepare (5R) -3- (3,4-diene-2-methoxyphenyl) -4,5-dimethyl-5- (trienomethyl) pentanitrile-2-one, the synthesis method is as follows:

Appropriate benzene-containing ring raw materials can be selected at the beginning, and the benzene ring can be modified to introduce specific substituents. The 3,4-diene structure is constructed at a specific position of the benzene ring before the benzene ring, which can be achieved by suitable nucleophilic substitution, elimination reaction, etc. In this process, the reaction conditions, such as temperature, solvent, catalyst, etc. are precisely controlled to ensure the correct formation of the diene structure and good regioselectivity.

Then 2-methoxy is introduced, and halogenated hydrocarbons can be used to react with methoxylation reagents under appropriate basic conditions to precisely replace methoxy groups in the target position.

As for the construction of 4,5-dimethyl-5- (trienomethyl) pentanitrile-2-one part, it can be started from a suitable chain compound. First, the methyl group is introduced by a suitable nucleophilic addition reaction, and the correct introduction of the 4,5-position methyl group is achieved by ingeniously designing the reaction sequence and conditions. After constructing the trienomethyl group, the alkylation reaction can be used, and the appropriate alkylation reagent can be selected to react with the intermediate. < Br >
The introduction of nitrile and carbonyl groups can be achieved by condensation and oxidation of suitable nitrile and carbonyl precursors. For example, the condensation reaction of aldosterone and nitrile-containing reagents can be used, and subsequent oxidation modification can be carried out to obtain the target 2-keto structure.

During the reaction process, it is necessary to always pay attention to the purification and identification of intermediates. The products are purified by methods such as column chromatography and recrystallization, and the structures are identified by means of nuclear magnetic resonance and mass spectrometry to ensure that each step of the reaction is carried out in the expected direction, so as to successfully synthesize (5R) -3- (3,4-diene-2-methoxyphenyl) -4,5-dimethyl-5- (trienomethyl) pentonitrile-2-one.

What are the physicochemical properties of (5R) -3- (3,4-difluoro-2-methoxyphenyl) -4,5-dimethyl-5- (trifluoromethyl) furan-2-one

(5R) -3- (3,4-diene-2-methoxyphenyl) -4,5-dimethyl-5- (trienomethyl) imidazole-2-one, this substance has unique physical and chemical properties. In terms of physical properties, it is mostly white to slightly yellow crystalline powder at room temperature, with a more delicate texture, like the shape of early winter snow. It has a certain melting point, about [X] ° C. When it reaches this temperature, it will change from solid to liquid like ice melting in a spring stream. And its density is moderate, compared with the density of common organic solvents, it has a specific value, which makes it have a unique distribution state in the solvent system. In terms of chemical properties, the diene structure contained in the molecular structure of the substance gives it a certain degree of unsaturation, which is reactive like a warrior. It can participate in many addition reactions, such as addition to halogen elements, hydrogen halides, etc., just like a warrior accepting new power. The methoxyphenyl structure makes it have a certain electrophilicity, and it can react with nucleophiles under appropriate conditions, just like yin and yang attract. The structure of imidazole-2-one determines its unique stability and reaction characteristics in acid-base environments. In weakly alkaline environments, its structure is relatively stable, just like a rock resisting the breeze; but in strongly acidic or strongly alkaline conditions, structural rearrangement or decomposition reactions will occur, just like a building changing in a storm. These physicochemical properties are intertwined and jointly determine the potential application value of (5R) -3- (3,4-diene-2-methoxyphenyl) -4,5-dimethyl-5- (trienomethyl) imidazole-2-one in organic synthesis, drug development and other fields.

What is the market price of (5R) -3- (3,4-difluoro-2-methoxyphenyl) -4,5-dimethyl-5- (trifluoromethyl) furan-2-one?

I don't know what you said about the market price of " (5R) -3- (3,4-diene-2-methoxybenzyl) -4,5-dimethyl-5- (trienomethyl) imidazole-2-one". However, if you want to know its price, you should follow everything.

First, this is a special organic compound, and its price may depend on purity. For high purity, it is difficult to prepare and expensive, and the price must be high; if the purity is slightly inferior, the price may be slightly reduced.

Second, market supply and demand are also important reasons. If the demand for this product is wide and the supply is thin, the price will rise; if the supply exceeds the demand, the price may drop.

Third, the difficulty of preparation also affects its price. The cumbersome synthesis steps and the rarity of raw materials all increase the cost and cause the price to be high.

In addition, the price of chemical products in the market changes frequently, or due to fluctuations in raw material prices, policy changes, and new technologies.

If you want to know the price, you can consult chemical product suppliers, professional chemical trading platforms, or industry experts. In this way, you can get a more accurate market price.

What are the manufacturers of (5R) -3- (3,4-difluoro-2-methoxyphenyl) -4,5-dimethyl-5- (trifluoromethyl) furan-2-one?

What is the manufacturer of (5R) -3- (3,4-diene-2-methoxyphenyl) -4,5-dimethyl-5- (trienomethyl) pyrimidine-2-one? I should use the classical style of "Tiangong Kaiwu" to explain this question for you.

Looking at the chemical map of the world, this (5R) -3- (3,4-diene-2-methoxyphenyl) -4,5-dimethyl-5- (trienomethyl) pyrimidine-2-one is produced by Xingluo from all over the world. In the land of the Central Plains, there are many excellent factories that specialize in chemical research. There are factories located in Jiangsu and Zhejiang, where the water network is vertical and horizontal, the convenience of boats is conducive to the transportation of materials, and the concentration of talents, the prosperity of science and technology, with exquisite craftsmanship and rigorous governance, the production of this compound has made quite a contribution.

There are also factories established in Qilu, the land of Qilu, which emphasizes education and learning, and there are many chemical schools, transporting many talents for the industry. Its factory relies on its profound technical heritage to manufacture (5R) -3- (3,4-diene-2-methoxyphenyl) -4,5-dimethyl-5- (trienomethyl) pyrimidine-2-ketone, which is also important in the industry.

Overseas domains, European and American states, also have factories that are good at making this thing. There is a first-mover technology, strong research and development force, and the products produced may have unique quality. However, the original manufacturers are striving to catch up, and with the excellent cost performance, they are gradually emerging in the international market.

Jifu, a land in the southwest, with mountains and rivers, abundant resources, there are also manufacturers in this layout, taking advantage of local advantages, dedicated to (5R) -3- (3,4-diene-2-methoxyphenyl) -4,5-dimethyl-5- (trienomethyl) pyrimidine-2-one production, hoping to make their own efforts to add luster to the industry.

All of these are manufacturers of (5R) -3- (3,4-diene-2-methoxyphenyl) -4,5-dimethyl-5- (trienomethyl) pyrimidine-2-one, which are located in various places and contribute to the chemical industry with different advantages.