What is the chemical structure of (2S, 3S, 4R) -methyl 4- ((3- (1-difluorobut-3-en-1-yl) -7-methoxyquinoxalin-2-yl) oxy) -3-ethylpyrrolidine-2-carboxylate 4-methylbenzenesulfonate

(The chemical structure description of this compound is lengthy and requires professional chemical drawing software to present, making it difficult to accurately express the structure in classical Chinese. The following describes its components and approximate relationships in a manner as close as possible)

This is a complex organic compound. Its main framework is pyrrolidine-2-carboxylate, with a carboxylic acid ester group at the 2nd position of the pyrrolidine ring, an ethyl group at the 3rd position, and a specific substituent at the 4th position. This substituent is composed of a quinoxaline group substituted with a fluoroalkenyl group, the quinoxaline ring is connected at 3 positions (1,1-difluorobutyl-3-ene-1-yl), and the 7-position methoxy group. And this compound also forms a salt with 4-methylbenzenesulfonic acid, and has a specific stereo configuration of (2S, 3S, 4R) as a whole. Although it is difficult to show the spatial relationship and precise connection of its chemical structure in detail in ancient Chinese, it can be roughly known that it is composed of a complex combination of polyfunctional groups, and each part is interrelated to construct this unique chemical entity. Each group is linked according to the bonding rules of organic chemistry, and coforms the structure of this unique compound.

What are the physical properties of (2S, 3S, 4R) -methyl 4- ((3- (1-difluorobut-3-en-1-yl) -7-methoxyquinoxalin-2-yl) oxy) -3-ethylpyrrolidine-2-carboxylate 4-methylbenzenesulfonate

(2S, 3S, 4R) -methyl 4- ((3- (1-difluorobut-3-en-1-yl) -7-methoxyquinoxalin-2-yl) oxy) -3-ethylpyrrolidine-2-carboxylate 4-methylbenzenesulfonate is an organic compound. Its physical properties are unique. This compound is mostly solid under normal conditions and has a fine texture. It may be white or nearly white powdery solid. This is due to the intermolecular force and crystal structure.

When it comes to melting point, due to the specific stability and interaction of the molecular structure, the melting point falls in a specific range, but the exact value needs to be determined by precise experiments. The compound exhibits different solubility to specific solvents. In polar organic solvents such as ethanol and acetone, it exhibits a certain solubility due to the hydrogen bonds formed between molecules and solvents, dipole-dipole interactions, etc.; in non-polar solvents such as n-hexane, the solubility is very small due to the mismatch between the intermolecular forces and the solvent.

Its density is determined by the molecular mass and the tightness of crystal stacking. Under specific conditions, the density value reflects the relationship between its mass and volume. This property is of great significance in chemical preparation, storage and transportation. In addition, the refractive index of the compound is also an important physical property, reflecting the refractive characteristics of light propagation in it, which is related to the distribution and structural order of the electron cloud of molecules, and has a profound impact on the research and development of optical materials. These physical properties lay the foundation for their applications in chemical synthesis, drug discovery, and many other fields.

What is the use of (2S, 3S, 4R) -methyl 4- ((3- (1-difluorobut-3-en-1-yl) -7-methoxyquinoxalin-2-yl) oxy) -3-ethylpyrrolidine-2-carboxylate 4-methylbenzenesulfonate

(2S, 3S, 4R) -methyl 4- ((3- (1,1-difluorobutyl-3-ene-1-yl) -7-methoxyquinoxaline-2-yl) oxy) -3-ethylpyrrolidine-2-carboxylate-4-methylbenzene sulfonate, which is a complex organic compound. Its use is quite extensive, in the field of medicine, or has the potential to treat specific diseases. Due to its unique chemical structure, it may interact with biological targets in the body, thereby regulating physiological processes and achieving therapeutic purposes.

In the process of drug development, such compounds are often key intermediates. With their special chemical properties, they can be converted into new drugs with better efficacy and fewer side effects through a series of chemical reactions. Chemists explore better pharmacological activities by modifying and optimizing their structures.

In the field of organic synthesis, it also plays an important role. As a synthetic building block, it can be used to build more complex organic molecular structures, providing an important foundation for the creation of novel functional materials and the total synthesis of natural products. Its structural properties expand many possibilities for organic synthesis chemistry, helping chemists achieve various complex molecular constructions and promoting the development of organic synthesis chemistry.

What is the synthesis method of (2S, 3S, 4R) -methyl 4- ((3- (1-difluorobut-3-en-1-yl) -7-methoxyquinoxalin-2-yl) oxy) -3-ethylpyrrolidine-2-carboxylate 4-methylbenzenesulfonate

To prepare (2S, 3S, 4R) -methyl-4- ((3- (1,1-difluorobutyl-3-ene-1-yl) -7-methoxyquinoxaline-2-yl) oxy) - 3-ethylpyrrolidine-2-carboxylate 4-methylbenzene sulfonate, the method is as follows:

First take 7-methoxyquinoxaline-2-ol, and halogen-containing 3- (1,1-difluorobutyl-3-ene-1 -Group) reagent, in the presence of a base, to cause the two to react. Alkali, such as potassium carbonate, sodium carbonate, etc., in a suitable organic solvent, such as N, N-dimethylformamide, heated and stirred to obtain 3- (1,1-difluorobutyl-3-ene-1-yl) -7-methoxyquinoxaline-2-yl ether intermediates.

times with (2S, 3S, 4R) -methyl-3-ethyl-4-hydroxypyrrolidine-2-carboxylate, and the resulting intermediates are connected with the help of coupling reagents. The coupling reagent can be selected from dicyclohexyl carbodiimide or the like. In an organic solvent such as dichloromethane, it is heated at room temperature or slightly to promote (2S, 3S, 4R) -methyl-4- ((3- (1,1-difluorobutyl-3-ene-1-yl) -7-methoxyquinoxaline-2-yl) oxy) -3-ethylpyrrolidine-2-carboxylic acid ester. At the end of

, this product is mixed and stirred with 4-methylbenzenesulfonic acid in a suitable solvent such as ether or ethyl acetate to form a salt to obtain the target product (2S, 3S, 4R) -methyl-4- ((3- (1,1-difluorobutyl-3-ene-1-yl) -7-methoxyquinoxaline-2-yl) oxy) -3-ethylpyrrolidine-2-carboxylate-4-methylbenzenesulfonate. After the reaction is completed, the pure product can be obtained by separation and purification methods, such as column chromatography and recrystallization.

(2S, 3S, 4R) -methyl 4- ((3- (1-difluorobut-3-en-1-yl) -7-methoxyquinoxalin-2-yl) oxy) -3-ethylpyrrolidine-2-carboxylate 4-methylbenzenesulfonate

This is a complex organic compound, and its safety information is quite important. At the toxicological level, the effects of this substance on the organism should be investigated. If ingested inadvertently, it may cause digestive system discomfort, such as nausea, vomiting, abdominal pain, etc., because it may interfere with digestive physiological processes.

Through skin contact, there is also a risk, or cause skin allergies, erythema, itching, because the skin may have an immune response to some of its groups.

And inhaled through the respiratory tract, this particle may irritate the respiratory tract, causing cough, asthma, or even more serious respiratory disorders, including its chemical structure or affecting the gas exchange between the respiratory mucosa and the lungs.

In terms of environmental safety, if this substance is released in the environment, it may have an impact on the aquatic ecosystem. Aquatic organisms, such as fish and plankton, are sensitive to this substance, or interfere with its normal physiology and reproduction, and destroy the ecological balance due to its complex structure or accumulation and metabolism in organisms.

It is also necessary to consider its behavior in the soil environment, or affect the activity of soil microorganisms, which in turn affects soil fertility and plant growth.

Therefore, all aspects of safety of this complex compound must be carefully considered to prevent it from harming life and the environment.