What is the chemical structure of (2R, 3R) -2- (2,4-difluorophenyl) -1- (1H-1,2,4-triazole-1-yl) butane-2,3-diol methanesulfonate

(2R, 3R) -2- (2,4-difluorophenyl) -1- (1H-1,2,4-triazole-1-yl) butyl-2,3-diol benzoate, its chemical structure is as follows.

This compound contains a chiral center and is in the (2R, 3R) configuration at the 2,3 carbon positions. Its main chain is a butane structure, linked to (2,4-difluorophenyl) at the 2 carbon position, and the 2,4 positions of this phenyl group are substituted by fluorine atoms. The 1-position carbon is connected with 1H-1,2,4-triazole-1-group, that is, the 1-position nitrogen atom of the 1,2,4-triazole ring is connected to the main chain. The 2 and 3-position carbons are respectively connected with hydroxyl groups, and both configurations are R. The 3-position carbon of the butane main chain is connected to the benzoate ester group, which is formed by esterification of the benzoic acid carboxyl group and the butane 3-position hydroxyl group. Overall, this compound combines fluorophenyl, triazolyl, diol structures with benzoate esters. The structure contains both aromatic ring conjugated system and chiral centers and ester groups. These structural characteristics endow it with unique physical and chemical properties, and may have important research value and potential applications in organic synthesis, medicinal chemistry and other fields.

What are the main uses of (2R, 3R) 2- (2,4-difluorophenyl) -1- (1H-1,2,4-triazole-1-yl) butane-2,3-diol methanesulfonate?

(2R, 3R) -2- (2,4-difluorophenyl) -1- (1H-1,2,4-triazole-1-yl) butyl-2,3-diol acetate, an organic compound. Its main uses are quite extensive. In the field of medicine, it is often used as a key intermediate in the synthesis of antifungal drugs. Many antifungal drugs use this compound to build a specific chemical structure to effectively inhibit fungal growth. The structure can be combined with specific targets in fungi, interfering with the normal physiological metabolism of fungi, thereby exerting antifungal effects.

In the field of pesticides, it also plays an important role. It can be used to synthesize some new fungicides, providing a strong guarantee for crops to resist the invasion of fungal diseases. With its unique chemical properties, it can effectively inhibit the reproduction of many common pathogenic fungi in crops, help improve crop yield and quality, and protect agricultural production.

Furthermore, in the field of organic synthetic chemistry research, (2R, 3R) -2- (2,4-difluorophenyl) -1- (1H-1,2,4-triazole-1-yl) butyl-2,3-diol acetate is often regarded as an important starting material or key intermediate. Scientists use the modification and transformation of their chemical structures to explore the synthesis of more organic compounds with novel structures and unique properties, promoting the continuous development of organic synthetic chemistry and laying the foundation for new materials, drug development and other fields.

What is the production process of (2R, 3R) -2- (2,4-difluorophenyl) -1- (1H-1,2,4-triazole-1-yl) butane-2,3-diol methanesulfonate?

(2R, 3R) -2- (2,4-difluorophenyl) -1- (1H-1,2,4-triazole-1-yl) butyl-2,3-diol acetate is an organic compound. Its preparation process is complicated, just like the ancient alchemy method, which requires multiple exquisite processes.

The first is the preparation of raw materials, just like the preparation of alchemy materials, to select high purity of 2,4-difluorobenzaldehyde, (2R, 3R) -2,3-butanediol and 1H-1,2,4-triazole and other raw materials, this is the cornerstone of preparation. < Br >
Then start the reaction, put 2,4-difluorobenzaldehyde and (2R, 3R) -2,3-butanediol into the reactor, add an appropriate amount of catalyst, such as carefully prepared alchemy herbs, at a specific temperature and pressure, catalyze the condensation reaction of the two. Temperature control is like adjusting the temperature of alchemy, which is crucial. Generally, it is necessary to maintain the temperature at 50-60 ° C, the pressure is about 1-2 atm, and the key intermediate is formed when the reaction number is.

Then the intermediate reacts with 1H-1,2,4-triazole. This step is like the fusion of two Dan, adding an acid binding agent to neutralize the acid generated by the reaction and ensure the smooth reaction. In a suitable solvent, such as dichloromethane or N, N-dimethylformamide, heat up to 80-90 ° C, and continue to react for 10-12 hours to obtain a mixture containing the target product.

Then separated and purified, such as purification of elixir after alchemy, using extraction, column chromatography and other means. First, it is extracted with an organic solvent to separate the organic phase from the aqueous phase, and then column chromatography is used to select silica gel as the stationary phase. A suitable eluent, such as a mixture of petroleum ether and ethyl acetate, is prepared in proportion, eluted and separated to obtain pure (2R, 3R) -2- (2,4-difluorophenyl) -1- (1H-1,2,4-triazole-1-yl) butyl-2,3-diol acetate.

At the end of the detection and characterization, the structure and purity of the product are determined by nuclear magnetic resonance, mass spectrometry and other instruments to ensure that it meets the requirements. This preparation process requires complicated steps and close correlation between each step. Strict control of conditions is required to obtain the target product.

What is the market outlook for (2R, 3R) 2- (2,4-difluorophenyl) -1- (1H-1,2,4-triazole-1-yl) butane-2,3-diol methanesulfonate?

Nowadays, there are\ ((2R, 3R) -2- (2,4-difluorophenyl) -1- (1H-1,2,4-triazole-1-yl) -1-butene-2,3-dimethylsuccinic anhydride\), and the market prospect of this product is related to many aspects.

It may have unique potential in the field of medicine. Because its structure contains specific groups, it may interact with specific targets in organisms.\ (1,2,4-triazole\) groups often exhibit various biological activities in drug molecules, such as antibacterial and antiviral effects. This compound may inhibit the growth and reproduction of some pathogens due to the group and surrounding structure, and then emerge in the development of antibacterial drugs. If developed properly, after being put into the market, it may be able to meet the clinical demand for new antibacterial drugs and fill the gaps in some fields. The prospect is quite promising.

In the field of pesticides, there are also opportunities.\ (2,4-difluorophenyl\) exists, or gives it good insecticidal and bactericidal properties. Nowadays, agricultural production has an increasing demand for high-efficiency, low-toxicity and environmentally friendly pesticides. If this compound is further studied and optimized, it may meet such needs and provide new options for crop pest control. If it can be recognized in marketing activities, it will open up a vast market.

However, its market prospects are also facing challenges. If the synthesis process is complex, if it is difficult to achieve efficient and low-cost production, even if the biological activity is excellent, it will be difficult to win market favor due to cost constraints. Furthermore, the market competition is fierce, and compounds of the same kind or similar efficacy may already occupy part of the market share. To stand out, you need to highlight your advantages in performance, price, environmental protection and other aspects. Only by responding properly can you gain a place in the market, and the prospect will be determined by many efforts and coping strategies.

(2R, 3R) 2- (2,4-difluorophenyl) -1- (1H-1,2,4-triazole-1-yl) butane-2,3-diol methanesulfonate What are the precautions during use?

(2R, 3R) -2- (2,4-difluorophenyl) -1- (1H-1,2,4-triazole-1-yl) butyl-2,3-diol acetate is a complex organic compound. In the process of use, many matters need to be paid attention to.

First, this compound may have specific chemical activity and reactivity. Because it contains fluorine atoms and triazole groups, under certain conditions, or chemically react with other substances. Therefore, when storing and using, it must be kept away from strong oxidants, strong acids, strong bases and other active substances to prevent unnecessary reactions, resulting in product deterioration or dangerous conditions.

Second, its solubility also needs to be paid attention to. Different solvents may have different solubility to them. When conducting reactions or preparing solutions, it is necessary to carefully select suitable solvents according to the purpose and requirements of the experiment. If the solvent is not selected properly, or the compound dissolves incompletely, it will affect the reaction process and experimental results.

Third, safety protection is indispensable. In view of the fact that many organic compounds have certain potential hazards to the human body, personal protective measures should be taken during operation, such as wearing protective gloves, goggles and masks. If you accidentally come into contact with the skin or eyes, you need to rinse with plenty of water immediately and seek medical attention in time according to the specific situation.

Fourth, accurate measurement and operation are extremely critical. Due to its complex structure, the reaction process or the amount of compounds required are strict. Therefore, when using, it is necessary to use precision measuring tools for measurement, and carry out experiments in strict accordance with the operating procedures to ensure the accuracy and repeatability of the experiments.

Finally, it is necessary to pay attention to its stability. When storing, it should be placed in a dry, cool and ventilated place to avoid light and high temperature to prevent the decomposition or deterioration of the compound and affect its performance.