Chemical Formula | C12H9F2N5O2S |
Appearance | Solid (usually white or off - white powder) |
Melting Point | Specific value would require experimental determination |
Solubility In Water | Low solubility in water |
Solubility In Organic Solvents | Soluble in some organic solvents like DMSO, DMF |
Pka | Data depends on the acidic/basic groups in the molecule |
Logp | Indicates lipophilicity, specific value needs calculation |
Stability | Stable under normal storage conditions away from heat, light, and oxidizing agents |
Chemical Formula | C12H10F2N6O2S |
Molecular Weight | 340.31 g/mol |
Appearance | Solid (description may vary) |
What is the main use of 2 ', 6' -difluoro-5-methyl [1,2,4] triazolo [1,5-a] pyrimidine-2-sulfoanilide
2% 27% 2C6% 27-difluoro-5-methyl [1,2,4] triazolo [1,5-a] pyrimidine-2-sulfonylaniline This substance is used as a herbicide in the field of agrochemistry.
The herbicide produced by this compound can effectively inhibit the growth of weeds. The reason for its action is based on delicate chemical properties and biological mechanisms. Weed growth depends on a variety of physiological processes, and this agent can target and interfere with key links.
For example, it may act on the relevant mechanisms of weed photosynthesis. Photosynthesis is the source of plant vitality and is related to energy uptake and material synthesis. If the agent affects the function of key proteins or enzymes in the photosynthetic system, weeds will be difficult to use light energy to produce nutrients, growth will be blocked, and gradually wither.
Or it may disturb the balance of weed hormones. Plant hormones regulate growth, development, flowering, and fruition. If this compound disrupts hormone synthesis, transport, or signal transduction, the growth rhythm of weeds will be chaotic, and it will be difficult to germinate, leaf, and head normally.
Because of its good herbicidal efficiency, it can remove many common weeds. In farmland, orchards, tea gardens, etc., it can protect crops from weeds competing for fertilizer, glory, and water, and ensure the robust growth of crops. Therefore, it is of great significance for agricultural production.
What are the synthesis methods of 2 ', 6' -difluoro-5-methyl [1,2,4] triazolo [1,5-a] pyrimidine-2-sulfoanilide
To prepare 2,6 '-difluoro-5-methyl [1,2,4] triazolo [1,5-a] pyrimidine-2-sulfonylaniline, there are many methods and each has its own strengths. The following are common synthesis paths.
Initially react with a suitable fluorinated raw material, such as a fluorohalogenated hydrocarbon or a fluoroaromatic hydrocarbon, with a substrate containing a pyrimidine structure. First, the nucleophilic substitution is carried out to introduce fluorine atoms into a specific position to build the basic skeleton. In the meantime, the temperature, solvent and catalyst of the reaction need to be precisely controlled. For example, in organic solvents, using bases as catalysts can promote the activity of nucleophiles and improve the reaction efficiency.
The structure of [1,2,4] triazolo [1,5-a] pyrimidine is also constructed by cyclization reaction with triazole compounds as starting materials. This process often requires a suitable dehydrating agent or condensing agent to promote the smooth progress of cyclization. For example, the use of strong dehydrating agents promotes intramolecular condensation to form a key heterocyclic structure. The sulfonylation step is also key. Sulfonyl chloride or sulfonate is used as the sulfonylation reagent and reacts with the intermediate obtained by the above reaction to introduce the sulfonyl group into the target position. Whether the reaction conditions are mild or not depends on the purity and yield of the product. An appropriate acid binding agent can be selected to absorb the acid generated by the reaction and promote the forward reaction. The
anilination reaction is the last critical step. Aniline or its derivatives are reacted with the sulfonylation product to form the final 2,6 '-difluoro-5-methyl [1,2,4] triazolo [1,5-a] pyrimidine-2-sulfonaniline. This step requires attention to the ratio of the reactants, reaction time and temperature to obtain the best reaction effect.
The whole process of synthesis, separation and purification cannot be ignored. Chromatographic columns, recrystallization and other means are often used to obtain high-purity target products. In this way, through multiple delicate reactions and fine operations, 2,6' -difluoro-5-methyl [1,2,4] triazolo [1,5-a] pyrimidine-2-sulfonaniline can be obtained.
What are the physicochemical properties of 2 ', 6' -difluoro-5-methyl [1,2,4] triazolo [1,5-a] pyrimidine-2-sulfoanilide
2% 27% 2C6% 27 - difluoro - 5 - methyl [1,2,4] triazolo [1,5 - a] pyrimidine - 2 - sulfoanilide is an organic compound. Its physical and chemical properties are very important and have applications in many fields such as chemical industry and medicine.
The properties of this compound are either solid under normal conditions, but the specific color state needs to be determined experimentally. The melting point is one of the key physical properties, and the melting point can reflect the strength of the intermolecular force. If the intermolecular force is strong and the lattice is stable, the melting point is higher; otherwise, it is lower. However, the specific melting point data of this compound has not been accurately recorded, and it needs to be accurately determined experimentally.
Solubility is also an important property. In organic solvents, such as common ethanol, dichloromethane, etc., its solubility may vary depending on molecular polarity. This compound contains heteroatoms such as fluorine, nitrogen, and sulfur, and has a certain polarity. It has good solubility in polar organic solvents, but poor solubility in non-polar solvents such as n-hexane. However, the exact solubility also needs to be verified experimentally.
In terms of chemical stability, this compound contains a triazolopyrimidine structure, which has a certain stability. However, the presence of fluorine atoms in its molecules may affect its chemical activity. Fluorine atoms are highly electronegative, or the electron cloud density of carbon atoms connected to them decreases, making this site more prone to reactions such as nucleophilic substitution. Under different acid and base conditions, its stability will also change. In strongly acidic or strongly alkaline environments, its structure may be damaged and reactions such as hydrolysis occur, but in neutral or near-neutral environments, its stability may be relatively good.
Its spectral properties are also worthy of attention. In infrared spectroscopy, the vibration of different chemical bonds produces characteristic absorption peaks. For example, the stretching vibration of nitrogen-containing heterocycles, the vibration related to fluorine atoms, etc., all have absorption peaks at specific wavenumbers, which can be used for structure identification. In nuclear magnetic resonance spectroscopy, hydrogen atoms and carbon atoms in different chemical environments will produce different chemical shifts, providing key information for their structure analysis. In conclusion, the physicochemical properties of 2% 27% 2C6% 27 - difluoro - 5 - methyl [1,2,4] triazolo [1,5 - a] pyrimidine - 2 - sulfoanilide need to be accurately determined and analyzed by many experiments, in order to lay the foundation for its practical application.
How competitive are 2 ', 6' -difluoro-5-methyl [1,2,4] triazolo [1,5-a] pyrimidine-2-sulfoanilide in the market?
Today, there are 2,6-difluoro-5-methyl [1,2,4] triazolo [1,5-a] pyrimidine-2-sulfonylaniline in the market. How competitive is it? This is a business question, and it is necessary to carefully observe all the elements in order to be clear.
First look at its characteristics. This compound may have a unique chemical structure and properties, and it may have unique effects in specific fields, such as agrochemistry and medicine. If it is used in agrochemistry, or it has high-efficiency control over certain pests and diseases, and is more environmentally friendly and long-lasting than other products; if it is used in medicine, it may be targeted at specific disease targets, with significant efficacy and minor side effects.
Second look at market supply and demand. If the current market demand for such compounds in the field is strong, but the supply is relatively scarce, this product may enter the market like a duck to water and become competitive. However, if the market is saturated and there are many competing products, it needs to break through with unique advantages.
Furthermore, depending on its cost and price. If the production process is advanced, the cost is controllable, the price can be closer to the people than the competing products, and the quality is not worried, it will be able to attract customers' favor and improve competitiveness.
There is also branding and marketing. If you can make good use of marketing techniques, spread your reputation, establish a high-quality brand perception, and make customers familiar and trustworthy, you can also gain an advantage in the competition.
Overall, the competitiveness of 2,6-difluoro-5-methyl [1,2,4] triazolo [1,5-a] pyrimidine-2-sulfonaniline cannot be determined in one word. It is necessary to weigh the characteristics, supply and demand, cost price, brand marketing and many other aspects in order to know its market position.
What are the potential application fields of 2 ', 6' -difluoro-5-methyl [1,2,4] triazolo [1,5-a] pyrimidine-2-sulfoanilide
2% 27% 2C6% 27-difluoro-5-methyl% 5B1% 2C2% 2C4% 5D triazolo% 5B1% 2C5-a% 5D pyrimidine-2-sulfonaniline, this compound has extraordinary applications in many fields.
In the field of medicine, it exhibits unique pharmacological activity. Due to its structural characteristics, it may be used as a potential drug lead compound. With precise action on specific biological targets, it can effectively regulate physiological and biochemical processes in organisms, or be beneficial to the treatment of certain diseases, such as targeting specific bacteria to cause diseases, or inhibiting the growth and reproduction of bacteria with unique structures, so as to achieve therapeutic purposes.
In the field of pesticides, it also has great potential. It can act on crop pests and pathogens by virtue of its own structure. Or it can interfere with the normal physiological activities of pests, such as hindering the signal transduction of the pest's nervous system, making it unable to eat, act normally, and eventually die; for pathogens, it can inhibit the activity of key metabolic enzymes, block the metabolic pathway of pathogens, limit their growth and transmission, and ensure the healthy growth of crops.
In the field of materials science, due to its specific chemical structure and physical properties, it can be used to prepare materials with unique functions. For example, in terms of polymer material modification, introducing it into the polymer system may change the electrical and optical properties of the material, so that the material has better application performance in electronic devices, optical components, etc., and improve the comprehensive properties of the material.
In short, 2% 27% 2C6% 27 -difluoro-5 -methyl% 5B1% 2C2% 2C4% 5D triazole% 5B1% 2C5 -a% 5D pyrimidine-2 -sulfonylaniline has broad application prospects in many fields such as medicine, pesticides, and materials science, and is worthy of in-depth exploration and development.