Chemical Formula | C6H2F5N |
Molar Mass | 185.08 g/mol |
Appearance | Colorless to light yellow liquid |
Boiling Point | Around 113 - 115 °C |
Solubility In Water | Poorly soluble in water, as it is an organic fluorinated compound |
Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
Chemical Formula | C6H2F5N |
Molecular Weight | 185.08 |
Appearance | Typically a colorless to pale - yellow liquid |
Boiling Point | Approximately 110 - 112°C |
Density | Data may vary, around 1.5 g/cm³ (estimated) |
Vapor Pressure | Relatively low, specific values depend on temperature |
Solubility | Slightly soluble in water, soluble in many organic solvents like dichloromethane, toluene |
Flash Point | Caution: Flammable, flash point data needed for safety handling |
Pka | No widely - known value, but pyridine ring can influence acidity - basicity behavior |
Odor | May have a characteristic pyridine - like odor |
What are the main uses of 2,3-difluoro-5- (trifluoromethyl) pyridine?
2% 2C3-diene-5- (trienomethyl) pyridine is a crucial intermediate in organic synthesis and is widely used in many fields.
In the field of medicinal chemistry, it can serve as a key structural module for creating drug molecules with specific biological activities. With its unique chemical structure, it can interact with specific targets in organisms or regulate specific physiological processes, opening up a broad path for the development of new drugs. For example, in the research of anti-tumor drugs, with the help of structural modification and modification, it is expected to obtain compounds with highly selective inhibitory activity on tumor cells.
In the field of materials science, 2% 2C3-diene-5- (trienomethyl) pyridine can participate in the preparation of functional polymer materials. Because of its double bond and pyridine structure, it can give the material unique electrical, optical or mechanical properties through polymerization or copolymerization with other monomers. For example, the preparation of polymers with photoelectric activity is used in organic Light Emitting Diode (OLED), solar cells and other photoelectric devices.
In organic synthetic chemistry, this compound acts as an intermediate, which can use its activity check point to carry out various chemical reactions and construct more complex organic molecular structures. For example, through nucleophilic substitution, addition, cyclization and other reactions, the synthesis of polyfunctional organic compounds is realized, providing organic synthesis chemists with rich synthesis strategies and methods, assisting in the synthesis of organic compounds with special structures and properties, and promoting the continuous development of organic synthesis chemistry.
What are the physical properties of 2,3-difluoro-5- (trifluoromethyl) pyridine?
2% 2C3-diene-5- (trienomethyl) pyridine is an organic compound. Its physical properties are as follows:
Under normal conditions, it may be a colorless to light yellow liquid with a special smell. However, this smell is not a pungent and unpleasant odor, but a slight aroma. It is like a subtle smell hidden in nature, which is not easy to detect but unique.
As far as the boiling point is concerned, it is about a certain temperature range. At this temperature, the compound gradually changes from liquid to gaseous. Due to the intermolecular forces and structural characteristics, its boiling point may be similar to that of similar structural compounds, but due to the specific atomic arrangement and chemical bonds, it is slightly different. This difference is its unique feature.
Melting point also has a specific value. When the temperature drops to this point, the substance solidifies from liquid to solid. This process is like a quiet transition, the molecules are gradually arranged in an orderly manner from the active state of motion, and a stable structure is built in the microscopic world.
In terms of solubility, in common organic solvents, such as ethanol and ether, there is a certain solubility. Due to the interaction between molecular polarity and solvent polarity, it is like two forces that are in harmony with each other, so that the compound can be uniformly dispersed in the solvent to form a uniform and stable system. However, in water, the solubility is not good, because the polarity of water and the molecular polarity of the compound do not match, and the two are like two parallel trajectories, which are difficult to blend. The density of
is different from that of water. It is placed in water, or floats on the surface of the water, or sinks on the bottom of the water. This is determined by its molecular mass and the degree of molecular accumulation. Just like an object sinks and floats in water, it depends on its own weight and volume.
The physical properties of this compound lay the foundation for its application in chemical synthesis, materials science and other fields. According to its properties, chemists can ingeniously design reactions to make it play a unique role and write a wonderful chapter in the transformation of matter in the microscopic world.
What are the synthesis methods of 2,3-difluoro-5- (trifluoromethyl) pyridine?
To prepare 2,3-diethyl-5- (triethylmethyl) pyridine, the following methods can be used:
First, the corresponding halogenated hydrocarbons and pyridine derivatives are used as raw materials and obtained by nucleophilic substitution reaction. Halogen atoms in halogenated hydrocarbons are highly active and can be substituted with atoms at specific positions on the pyridine ring. By ingeniously designing the reaction check point, the hydrocarbon groups of the halogenated hydrocarbons can be successfully connected to the pyridine ring to build the basic structure of the target product. This process requires careful selection of halogenated hydrocarbons and pyridine derivatives, and strict control of reaction conditions, such as temperature, solvent and catalyst dosage, will affect the reaction process and yield.
Second, it is achieved by the coupling reaction catalyzed by transition metals. Transition metal catalysts can activate the reactant molecules and promote the formation of carbon-carbon bonds or carbon-hetero bonds. In this synthesis, the selection of specific transition metal catalysts, such as palladium, nickel, etc., with suitable ligands, can effectively improve the selectivity and efficiency of the reaction. The substrate containing pyridine structure and electrophilic reagents with ethane group and triethyl methyl group are used as raw materials, and the coupling reaction occurs under transition metal catalysis to precisely construct the structure of the target molecule. Although this method has the advantages of high efficiency and high selectivity, the catalyst cost is higher, and the reaction equipment and operation requirements are also stricter.
Third, from the perspective of the construction of the pyridine ring, the target molecule is gradually built in a multi-step reaction. The prototype of the pyridine ring is first synthesized from a simple raw material, and then ethyl and triethyl are introduced through alkylation. For example, the pyridine ring can be constructed by condensation reaction, and then the desired hydrocarbon group can be introduced through reaction such as Fu-gram alkylation. This strategy requires precise control of each step of the reaction to ensure the purity and yield of the product in each step. Although the steps are cumbersome, the requirements for the reaction conditions are relatively mild, and the raw materials are easy to obtain.
What are the precautions for storing and transporting 2,3-difluoro-5- (trifluoromethyl) pyridine?
2% 2C3-diethyl-5- (triethylmethyl) pyridine needs to pay attention to many key matters during storage and transportation.
Suitable environment first. This substance should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Because of its flammability, high temperature and open flame are easy to cause combustion or even explosion.
The second is the tightness of the packaging. Be sure to ensure that the packaging is not damaged or leaked. Packaging materials need to be adapted to effectively protect the substance and prevent external factors such as air and moisture from interfering. If poor packaging causes leakage, it will not only waste materials, but also pollute the environment and endanger personnel safety.
In addition, when storing, pay attention to isolation from other substances. Do not mix with oxidants, acids, alkalis, etc. Because of its active chemical properties, contact with these substances or severe chemical reactions can be dangerous.
During transportation, caution is also required. The means of transportation must meet safety standards and have measures such as fire prevention and explosion protection. When loading and unloading, it should be handled with care to avoid packaging damage caused by collisions and falls. Transport personnel should be professionally trained, familiar with the characteristics of the substance and emergency treatment methods, and able to respond appropriately in case of emergencies.
In conclusion, 2% 2C3 -diethyl-5- (triethyl) pyridine requires all-round attention to the environment, packaging, isolation, and personnel operation during storage and transportation to ensure the safety of the process.
What is the market price of 2,3-difluoro-5- (trifluoromethyl) pyridine?
Today there are 2,3-diene-5- (trienomethyl) pyridine, what is the price in the market?
The principle of business is that the price is determined, not the only reason. The first is its quality, the quality is excellent, and the price is high. If this pyridine is pure and less heterogeneous, its price will be higher than that of regular products. Second, supply and demand, oversupply, the price will fall; if supply exceeds demand, the price will rise. If there are many people in need of this pyridine in the market, but there are few producers, the price will rise; if there are many products, and those who use it are rare, the price will drop from the bottom.
And the cost of production is also related to the price. If you choose good materials and work meticulously, the cost will be high, and the price will follow. And the cost of transportation and taxation will all enter the cost, which will affect the price. If the origin is remote and the cost of losing is huge, the price will increase.
Furthermore, the price varies depending on the time. Market fluctuations, the rise and fall of the industry, can make the price rise and fall. When the time is good, the industry is prosperous, and the price may rise; if the luck is bad, the industry is weak, and the price may fall.
In summary, the market price of 2,3-diene-5- (trienomethyl) pyridine is difficult to determine, and it is necessary to carefully examine the quality, supply and demand, cost, and changes in luck.