Chemical Name | 1H-Benzimidazole, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]- |
Molecular Formula | C17H16F2N4O4S |
Molecular Weight | 410.396 g/mol |
Appearance | Typically a solid |
Melting Point | Varies, needs experimental determination |
Solubility | Solubility characteristics depend on solvents; may be sparingly soluble in water |
Pka | Data specific to this compound would require experimental measurement |
Logp | Estimated value would depend on computational methods or experimental determination |
Density | Value requires experimental measurement |
Chemical Name | 1H-Benzimidazole, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]- |
Molecular Formula | C19H18F2N4O4S |
Molecular Weight | 438.437 g/mol |
Appearance | Typically a solid (physical state may vary based on conditions) |
Melting Point | Data may vary depending on purity and experimental method |
Solubility | Solubility characteristics depend on solvents; may have limited solubility in water, better solubility in some organic solvents |
Pka | Specific pKa values related to its acidic or basic groups would require experimental determination |
Logp | A measure of lipophilicity, data would need experimental determination |
Density | Value would depend on the physical form and conditions, requires experimental measurement |
What is the chemical structure of 1H-Benzimidazole, 6- (difluoromethoxy) -2- [[ (4-dimethoxy-2-pyridinyl) methyl] sulfinyl] -
This is a 1H-benzimidazole compound, and its chemical structure is quite complex and delicate. According to the description, this compound has a difluoromethoxy group at the 6th position, and a [ (3,4-dimethoxy-2-pyridyl) methyl] sulfinyl group at the 2nd position.
Benzimidazole, originally a five-membered nitrogen heterocycle fused with a benzene ring, has a unique chemical activity and spatial configuration. On this basis, difluoromethoxy is added at the 6th position. The fluorine atom in the difluoromethoxy group has high electronegativity, which can significantly change the electron cloud density of the benzimidazole ring and affect its chemical reaction activity and biological activity.
And the 2-position is connected to [ (3,4-dimethoxy-2-pyridyl) methyl] sulfinyl, the pyridine ring is also a nitrogen-containing heterocycle, the 3,4-bit methoxy group can further regulate the distribution of electron clouds, and the sulfinyl group imparts specific nucleophilic and electrophilic properties to the compound, and interacts with the benzimidazole ring to make the whole molecule exhibit special chemical properties and potential biological activities, which may have important applications in pharmaceutical chemistry, materials chemistry and other fields.
What are the physical properties of 1H-Benzimidazole, 6- (difluoromethoxy) -2- [[ (4-dimethoxy-2-pyridinyl) methyl] sulfinyl] -
1H-benzimidazole, 6- (difluoromethoxy) -2- [ (3,4-dimethoxy-2-pyridyl) methyl] sulfinyl, this material has the following physical properties:
Its appearance is mostly white to off-white crystalline powder, just like the new snow that falls in the early winter, pure and delicate. The melting point is usually within a specific range, about [X] ° C to [X] ° C. It is like a precisely calibrated scale, and the phase state changes at a specific temperature node.
In terms of solubility, in organic solvents, such as methanol and ethanol, it can show good solubility, like a duck to water, quietly integrated into it. In water, its solubility is relatively low, as if it is inseparable from water.
density is also an important physical property, about [X] g/cm ³, as if carrying its own unique weight code. Its stability is relatively good, under the conventional temperature and humidity environment, it is like a gentleman who is calm and can maintain its own structure and properties. However, if it encounters strong acid and alkali environments, and is like a fragile flower, its structure may be damaged, causing changes in properties. And it also has a certain sensitivity to light. Under long-term exposure to strong light, photochemical reactions may occur, resulting in gradual changes in properties.
What are the application fields of 1H-Benzimidazole, 6- (difluoromethoxy) -2- [[ (4-dimethoxy-2-pyridinyl) methyl] sulfinyl] -
1H-benzimidazole, 6- (difluoromethoxy) -2- [ (3,4-dimethoxy-2-pyridyl) methyl] sulfinyl This substance is of extraordinary use in the medical tract. It is quite powerful in the healing of gastrointestinal diseases.
The symptoms related to gastric acid, such as gastric ulcers and duodenal ulcers, all depend on this substance to check the secretion of gastric acid. In the stomach, excessive stomach acid often causes ulcers, and the pain is inexplicable. This substance can cleverly regulate the mechanism of gastric acid production, so that gastric acid secretion is peaceful, gastric mucosa can be protected from erosion, ulcers gradually heal, and the pain of patients is also relieved.
As for the symptoms of reflux esophagitis, it is also in the scope of treatment of this substance. The esophagus is inflamed due to acid reflux, and patients often feel heartburn and chest pain. This substance can reduce the invasion of gastric acid, relieve esophageal inflammation, and restore the esophagus to a healthy state.
Furthermore, in gastrointestinal diseases caused by Helicobacter pylori infection, this substance can also cooperate with antibiotics and other drugs to eliminate bacteria. Helicobacter pylori exists in the stomach and is the root cause of many gastrointestinal diseases. In combination with other medicines, it can create an environment that is not suitable for the survival of pathogens, thereby removing them and helping the gastrointestinal tract to resume normal transportation and transformation.
It can be seen that 1H-benzimidazole, 6- (difluoromethoxy) -2- [ (3,4-dimethoxy-2-pyridyl) methyl] sulfinyl groups have significant effects in the treatment of various gastrointestinal diseases, and are a powerful medicine for doctors to treat gastrointestinal diseases.
What is the synthesis method of 1H-Benzimidazole, 6- (difluoromethoxy) -2- [[ (4-dimethoxy-2-pyridinyl) methyl] sulfinyl] -
To prepare 6 - (difluoromethoxy) - 2 - [ (3,4 - dimethoxy - 2 - pyridyl) methyl] sulfinyl - 1H - benzimidazole, the method is as follows:
First, all kinds of raw materials need to be prepared, such as benzimidazole derivatives containing specific substituents, pyridine compounds with corresponding structures, etc. The quality of the raw materials is the most critical, and it must be pure to ensure a smooth reaction.
The reaction starts, usually in a suitable reaction vessel, dissolved in an organic solvent. The selected solvent, when compatible with the reactants and does not disturb the reaction.
Then, add an appropriate amount of alkali substances to catalyze the reaction. The amount and type of alkali are carefully determined according to the reaction characteristics. Alkali can promote the activity of reactants and lead them to interact.
Heat up to a specific temperature to make the reaction system reach an activated state. It is very important to precisely control the temperature. If it is too high or causes side reactions to occur, if it is too low, the reaction will be delayed.
During the reaction, closely observe and observe the reaction process by thin layer chromatography or other analytical methods. When the raw materials are converted as expected, stop it at the right time.
After the reaction is completed, the product is separated and purified. Extraction, column chromatography, etc. are often used to remove impurities and obtain a pure product. During extraction, the appropriate extractant is selected to lift the product from the reaction system to the organic phase. Column chromatography is based on the polarity difference between the product and the impurities to In this way, the product of 6 - (difluoromethoxy) - 2 - [ (3,4 - dimethoxy - 2 - pyridyl) methyl] sulfinyl - 1H - benzimidazole can be obtained through various steps. Careful operation is required at each step to ensure efficient reaction and pure product.
1H-Benzimidazole, 6- (difluoromethoxy) -2- [[ (4-dimethoxy-2-pyridinyl) methyl] sulfinyl] - What is the market outlook?
Guanfu 6- (difluoromethoxy) -2- [ (3,4-dimethoxy-2-pyridyl) methyl] sulfinyl-1H-benzimidazole is of great value in the current market prospect.
Because of its unique chemical structure, the difluoromethoxy, sulfinyl and other groups involved endow it with diverse chemical activities. In the field of pharmaceutical research and development, such structures often have potential biological activities, or can act on specific biological targets, and are expected to be developed into new drugs, such as anti-ulcer, anti-tumor and other drug categories. In view of the current pharmaceutical market demand, new and efficient drugs with small side effects are in high demand. If this compound is deeply researched and developed, it can demonstrate good pharmacological activity and safety, and will be able to occupy a place in the pharmaceutical market. The future is bright.
Furthermore, in the chemical industry, its unique structure may be applied to the synthesis of fine chemicals, as a key intermediate, derived a variety of high value-added products. The chemical industry has always pursued innovation and efficiency. Such special structural compounds may bring new changes and breakthroughs to the chemical synthesis path to meet the needs of high-end chemical products.
However, it must also be observed that its marketing activities and applications also face many challenges. The optimization of the synthesis process is crucial. If the synthesis process is complex and expensive, it is difficult to achieve large-scale production, limiting its market expansion. And drug development requires long and rigorous clinical trials to prove its safety and effectiveness. This process is expensive and requires strong financial and technical support.
Although there are challenges ahead, 6- (difluoromethoxy) -2- [ (3,4-dimethoxy-2-pyridyl) methyl] sulfinyl-1H-benzimidazolium has its own unique structural advantages in the fields of medicine and chemical industry. If it can be properly researched and developed, it will be able to bloom in the market and contribute to the development of the industry.