1 5 2 6 Difluorophenyl 4 5 Dihydro 1 2 Oxazol 3 Yl Ethanone
Fluorine Difluoride Fluorobenzene Fluorobenzyl Trifluorotoluene
1-[5-(2,6-difluorophenyl)-4,5-dihydro-1,2-oxazol-3-yl]ethanone
Chemical Formula C11H9F2NO2
Molecular Weight 225.192 g/mol
Solubility In Water Expected to be low due to non - polar aromatic part
Solubility In Organic Solvents Likely soluble in common organic solvents like dichloromethane, chloroform
Chemical Formula C11H9F2NO2
Molecular Weight 227.192 g/mol
Appearance Solid (predicted)
Boiling Point Predicted to be in a certain range (needs experimental determination)
Melting Point Predicted to be in a certain range (needs experimental determination)
Solubility In Water Low solubility (predicted)
Solubility In Organic Solvents Soluble in some common organic solvents like dichloromethane (predicted)
Density Predicted to be in a certain range (needs experimental determination)
Vapor Pressure Low vapor pressure (predicted)
Pka Predicted to be in a certain range (needs experimental determination)
FAQ

What is the main use of 1- [5- (2,6-difluorophenyl) -4,5-dihydro-1,2-oxazole-3-yl] ethyl ketone?

1-% [5- (2,6-diethylphenyl) -4,5-dihydro-1,2-oxazine-3-yl] ethylsulfonic acid, the main use of this material, is in the "Tiangong Kaiwu" described in various industries, has its place.

In the printing and dyeing industry, it can be used as an auxiliary. Gain 1-% [5- (2,6-diethylphenyl) -4,5-dihydro-1,2-oxazine-3-yl] ethylsulfonic acid has unique chemical properties, which can help dyes dye more evenly on fabrics, making the dyed color brighter and longer lasting. After the fabric is treated, the color fastness can be improved, and it is not easy to fade under washing or light. This is a great contribution to the improvement of the quality of the fabric.

Furthermore, in some fine chemical synthesis, it is also a key raw material. Based on this, other compounds with special properties can be prepared through a series of chemical reactions. For example, some intermediates with special solubility or reactivity can precisely adjust the structure and properties of the products through their participation in the reaction to meet the needs of different fields for special chemicals.

And in the field of material surface modification, 1-% [5- (2,6-diethylphenyl) -4,5-dihydro-1,2-oxazine-3-yl] ethylsulfonic acid can also play a role. Applied to the surface of the material, it can change the surface tension, wettability and other properties of the material. In this way, the compatibility of the material with other substances can be improved, and in the preparation of composites, it can promote closer bonding between the components and improve the overall performance of the material.

What are the synthesis methods of 1- [5- (2,6-difluorophenyl) -4,5-dihydro-1,2-oxazole-3-yl] ethyl ketone?

To prepare 1 - [5- (2,6-diethylphenyl) -4,5-dihydro-1,2-oxazole-3-yl] acetonitrile, the synthesis method is as follows:

First, key intermediates can be constructed through a series of organic reactions. For the aryl moiety, the coupling reaction of suitable halogenated aromatics with diethylphenyl-containing reagents under the catalysis of transition metals, such as the Suzuki coupling catalyzed by palladium or the Ullmann reaction catalyzed by copper, can introduce 2,6-diethylphenyl. This step requires precise regulation of the reaction conditions to ensure that the reaction is efficient and selective. Solvent selection, base type and temperature control are all crucial.

When constructing an oxazole ring, raw materials containing nitrogen and oxygen atoms can be used with carbonyl compounds, which can be condensed and cyclized under acid or base catalysis. If a suitable amino alcohol is reacted with an acid chloride or an acid anhydride, the oxazole ring structure is formed through the molecular inner pass ring. During the reaction process, attention should be paid to the proportion of raw materials and the reaction sequence to prevent side reactions from occurring, such as avoiding the formation of polymers or other cyclized isomers.

When introducing the acetonitrile part, a nucleophilic substitution reaction can be used. The obtained oxazole ring-containing intermediate reacts with halogenated acetonitrile under basic conditions, so that the halogen atom is replaced, thereby connecting the acetonitrile group. In this step, the reaction temperature and the strength of the base should be controlled to prevent unnecessary reactions in oxazole ring opening or other parts.

In the whole synthesis route, strict separation and purification are required after each step, and high-purity intermediates and target products are obtained by means of column chromatography and recrystallization. The optimization of the reaction conditions of each step needs to be finely adjusted according to the characteristics of the substrate, the reaction mechanism and the actual experimental results to achieve the efficient synthesis of 1 - [5- (2,6-diethylphenyl) -4,5-dihydro-1,2-oxazole-3-yl] acetonitrile.

What are the physicochemical properties of 1- [5- (2,6-difluorophenyl) -4,5-dihydro-1,2-oxazole-3-yl] ethyl ketone?

The "1 - [5- (2,6-diethylphenyl) -4,5-diketone-1,2-oxazole-3-yl] acetic acid" involved in this question is an organic compound. Its physical and chemical properties are particularly important and are related to its application in many fields.

In terms of its physical properties, at room temperature, or as a solid, the specific state depends on its intermolecular force and structure. Its melting point and boiling point are also determined by the interactions between molecules and molecules, such as hydrogen bonds, van der Waals forces, etc. If the intermolecular force is strong, the melting point and boiling point are higher.

Looking at its chemical properties, due to its carboxyl group (-COOH), it is acidic and can neutralize with bases to form corresponding carboxylic salts and water. If reacted with sodium hydroxide, it forms 1- [5- (2,6-diethylphenyl) -4,5-diketone-1,2-oxazole-3-yl] sodium acetate and water. And because of other functional groups in its structure, it can participate in various chemical reactions, such as substitution reactions. Hydrogen atoms on aromatic rings can be replaced by other atoms or groups under appropriate conditions, or participate in cyclization, addition and other reactions due to functional groups such as diketones and oxazoles, and have the potential to construct complex structures in the field of organic synthesis. Its chemical activity and stability are important in the fields of organic synthesis and drug development. Researchers can design synthetic pathways or explore its biological activity and pharmacological effects according to its properties.

What is the market price of 1- [5- (2,6-difluorophenyl) -4,5-dihydro-1,2-oxazole-3-yl] ethanone?

There is a medicine today, named 1- [5- (2,6-diethylphenyl) -4,5-dioxy-1,2-oxazole-3-yl] acetic acid, what is the price in the market? And as mentioned in "Tiangong Kaiwu", the price of the product often changes due to various reasons. However, this medicine has not been heard in "Tiangong Kaiwu", and the cover is different, and the product is also different.

Looking at the city in this world, the setting of the price of the drug is related to many factors. First, the manufacturing cost of the drug. To make this drug, you need to use raw materials, whether the source is rare or numerous, and the difficulty and expense of collecting are all costs. The process of making it requires exquisite skills, good tools, and the cost of labor and equipment, which are also important items. Second, the supply and demand of the city. If this medicine is effective in treating diseases, if there are many people seeking it, but there are few producers, the price will increase; if the supply exceeds the demand, the price may drop. Third, the regulations of the government. The government has established regulations on the preparation and sale of medicines, and the severity of taxes can also make the price different.

However, I do not know the current market situation of this medicine, so it is difficult to determine its price. If you want to know, you should consult the merchants of pharmaceutical stores, or check the reports of the pharmaceutical market, in order to obtain its approximate price.

What are the application fields of 1- [5- (2,6-difluorophenyl) -4,5-dihydro-1,2-oxazole-3-yl] ethyl ketone

1-% 5B5-% 282,6-Diethylphenyl% 29-4,5-dioxy-1,2-oxazole-3-yl% 5D acetic acid has a wide range of application fields. This compound is often used in the field of medicinal chemistry and is often a key intermediate in drug synthesis. Due to its unique chemical structure, it can be cleverly spliced with other molecular fragments through specific reaction pathways to construct drug molecules with specific physiological activities, or used to develop anti-tumor drugs, by precisely acting on specific targets of tumor cells, interfering with tumor cell growth and proliferation; or used to create drugs for the treatment of nervous system diseases, modulating neurotransmitter transmission, and improving related symptoms.

In the field of materials science, 1-% 5B5-% 282,6-diethylphenyl% 29-4,5-dioxo-1,2-oxazole-3-yl% 5D acetic acid can participate in the synthesis of polymer materials. After polymerization, it is introduced into the main chain or side chain of the polymer to endow the material with novel properties, such as improving the thermal stability of the material, so that the material can still maintain good physical and mechanical properties in high temperature environments. It is used in aerospace, electronics and other fields that require strict heat resistance of materials; or to enhance the optical properties of the material, so that the material has a specific optical response, used in optical sensors, photoluminescent materials, etc.

In the field of organic synthetic chemistry, this compound, as a unique reaction substrate, can participate in a variety of organic reactions, such as cyclization reactions, addition reactions, etc., providing an effective way to construct complex organic molecular structures. By rationally designing reaction routes and using their structural characteristics, efficient synthesis of target products can be achieved, providing new methods and strategies for the development of organic synthetic chemistry.